Iris. Augustin, et.al., Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis., The Journal of experimental medicine, 2013, 210

http://rdf.ncbi.nlm.nih.gov/pubmed/23918954

Iris. Augustin, et.al., Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis., The Journal of experimental medicine, 2013, 210

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1.1(Wls/YFP)Mbtr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5547722
• Wls<tm1.1Arte>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5547720

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• embryonic lethality, complete penetrance_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Tg(CMV-cre)1Cgn/?
  http://metadb.riken.jp/0011092IBALBcJC57BL6Wlstm11ArteWlstm11ArteTgCMVcre1CgnTgCMVcre1CgnWlstm11Arte
• increased double-negative T cell number_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0005090I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• scaly skin_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0001192I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• abnormal T cell physiology_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0002444I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• increased mast cell number_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0000324I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• decreased hair follicle number_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0000379I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• thin dermal layer_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0001244I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• skin inflammation_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0004947I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• abnormal eye morphology_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0002092I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• thin skin_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0001199I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• abnormal nose morphology_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0002233I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• abnormal ear morphology_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0002102I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• abnormal skin physiology_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0005501I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• thymus atrophy_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0003644I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• increased macrophage cell number_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0005425I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• premature death_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• decreased T cell number_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0005018I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• thin hypodermis_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0004126I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• impaired skin barrier function_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0002796I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• decreased thymus weight_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0004956I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• increased neutrophil cell number_Ctnnb1<tm4Wbm>/Ctnnb1<tm4Wbm>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0000219I129P2OlaHsdCtnnb1tm4WbmCtnnb1tm4WbmKrt14tm1creWbmKrt14Ctnnb1tm4WbmKrt14Krt14tm1creWbm
• abnormal hair growth_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0002073I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• abnormal T cell subpopulation ratio_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0003944I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• hair follicle degeneration_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0003413I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• increased neutrophil cell number_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0000219I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• abnormal skin appearance_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0009931I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• abnormal T cell differentiation_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0002145I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• postnatal growth retardation_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0001732I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• decreased neutrophil cell number_Gt(ROSA)26Sor<tm1.1(Wls/YFP)Mbtr>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000222IC57BL6GtROSA26Sortm11WlsYFPMbtrGtROSA26SorGtROSA26Sortm11WlsYFPMbtrGtROSA26Sor
• epidermal spongiosis_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0009795I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• increased T cell proliferation_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0005348I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• thymus hypoplasia_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0001823I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• decreased body size_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0001265I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• small thymus medulla_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0013588I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• reddish skin_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0001190I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• abnormal adipose tissue physiology_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0005666I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• sparse hair_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Tg(Foxn1-cre)1Tbo/0
  http://metadb.riken.jp/0000416IC57BL6Wlstm11ArteWlstm11ArteTgFoxn1cre1Tbo0TgFoxn1cre1TboWlstm11Arte
• decreased double-positive T cell number_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0005092I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• decreased gamma-delta T cell number_Ctnnb1<tm4Wbm>/Ctnnb1<tm4Wbm>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0008347I129P2OlaHsdCtnnb1tm4WbmCtnnb1tm4WbmKrt14tm1creWbmKrt14Ctnnb1tm4WbmKrt14Krt14tm1creWbm
• sparse hair_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0000416I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• flaky skin_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0001195I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• decreased gamma-delta T cell number_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0008347I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• increased keratinocyte proliferation_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0009583I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte
• decreased body surface temperature_Wls<tm1.1Arte>/Wls<tm1.1Arte>,Krt14<tm1(cre)Wbm>/Krt14<+>
  http://metadb.riken.jp/0011015I129P2OlaHsdC57BL6Wlstm11ArteWlstm11ArteKrt14tm1creWbmKrt14Krt14tm1creWbmKrt14Wlstm11Arte

class

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1.1(Wls/YFP)Mbtr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5547722
• Wls<tm1.1Arte>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5547720