Emmanuelle. Vidal-Petiot, et.al., WNK1-related Familial Hyperkalemic Hypertension results from an increased expression of L-WNK1 specifically in the distal nephron., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110

http://rdf.ncbi.nlm.nih.gov/pubmed/23940364

Emmanuelle. Vidal-Petiot, et.al., WNK1-related Familial Hyperkalemic Hypertension results from an increased expression of L-WNK1 specifically in the distal nephron., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Wnk1<tm2.1Juha>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5544571

class

http://purl.org/net/cito/citesAsAuthority

• Wnk1<tm2.1Juha>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5544571

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal distal convoluted tubule morphology_Wnk1<tm2.1Juha>/Wnk1<+>,Tg(Pgk1-cre)1Lni/0
  http://metadb.riken.jp/0004757I129S2SvPasBALBcC57BL6SJLWnk1tm21JuhaWnk1TgPgk1cre1Lni0Wnk1tm21JuhaWnk1TgPgk1cre1Lni
• hyperkalemia_Wnk1<tm2.1Juha>/Wnk1<+>,Tg(Pgk1-cre)1Lni/0
  http://metadb.riken.jp/0012339I129S2SvPasBALBcC57BL6SJLWnk1tm21JuhaWnk1TgPgk1cre1Lni0Wnk1tm21JuhaWnk1TgPgk1cre1Lni
• increased urine calcium level_Wnk1<tm2.1Juha>/Wnk1<+>,Tg(Pgk1-cre)1Lni/0
  http://metadb.riken.jp/0005441I129S2SvPasBALBcC57BL6SJLWnk1tm21JuhaWnk1TgPgk1cre1Lni0Wnk1tm21JuhaWnk1TgPgk1cre1Lni
• increased urine aldosterone level_Wnk1<tm2.1Juha>/Wnk1<+>,Tg(Pgk1-cre)1Lni/0
  http://metadb.riken.jp/0011540I129S2SvPasBALBcC57BL6SJLWnk1tm21JuhaWnk1TgPgk1cre1Lni0Wnk1tm21JuhaWnk1TgPgk1cre1Lni
• increased systemic arterial systolic blood pressure_Wnk1<tm2.1Juha>/Wnk1<+>,Tg(Pgk1-cre)1Lni/0
  http://metadb.riken.jp/0006144I129S2SvPasBALBcC57BL6SJLWnk1tm21JuhaWnk1TgPgk1cre1Lni0Wnk1tm21JuhaWnk1TgPgk1cre1Lni
• abnormal kidney physiology_Wnk1<tm2.1Juha>/Wnk1<+>,Tg(Pgk1-cre)1Lni/0
  http://metadb.riken.jp/0002136I129S2SvPasBALBcC57BL6SJLWnk1tm21JuhaWnk1TgPgk1cre1Lni0Wnk1tm21JuhaWnk1TgPgk1cre1Lni
• decreased hematocrit_Wnk1<tm2.1Juha>/Wnk1<+>,Tg(Pgk1-cre)1Lni/0
  http://metadb.riken.jp/0000208I129S2SvPasBALBcC57BL6SJLWnk1tm21JuhaWnk1TgPgk1cre1Lni0Wnk1tm21JuhaWnk1TgPgk1cre1Lni
• metabolic acidosis_Wnk1<tm2.1Juha>/Wnk1<+>,Tg(Pgk1-cre)1Lni/0
  http://metadb.riken.jp/0012551I129S2SvPasBALBcC57BL6SJLWnk1tm21JuhaWnk1TgPgk1cre1Lni0Wnk1tm21JuhaWnk1TgPgk1cre1Lni
• increased circulating chloride level_Wnk1<tm2.1Juha>/Wnk1<+>,Tg(Pgk1-cre)1Lni/0
  http://metadb.riken.jp/0003019I129S2SvPasBALBcC57BL6SJLWnk1tm21JuhaWnk1TgPgk1cre1Lni0Wnk1tm21JuhaWnk1TgPgk1cre1Lni