Walker S. Jackson, et.al., Profoundly different prion diseases in knock-in mice carrying single PrP codon substitutions associated with human diseases., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110

http://rdf.ncbi.nlm.nih.gov/pubmed/23959875

Walker S. Jackson, et.al., Profoundly different prion diseases in knock-in mice carrying single PrP codon substitutions associated with human diseases., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Prnp<tm3Lnq>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5546407

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal voluntary movement_Prnp<tm3Lnq>/Prnp<tm3Lnq>
  http://metadb.riken.jp/0003491I129P2OlaHsdC57BL6NPrnptm3LnqPrnptm3LnqPrnptm3Lnq
• astrocytosis_Prnp<tm3Lnq>/Prnp<tm3Lnq>
  http://metadb.riken.jp/0003354I129P2OlaHsdC57BL6NPrnptm3LnqPrnptm3LnqPrnptm3Lnq
• neuron degeneration_Prnp<tm3Lnq>/Prnp<tm3Lnq>
  http://metadb.riken.jp/0003224I129P2OlaHsdC57BL6NPrnptm3LnqPrnptm3LnqPrnptm3Lnq
• abnormal neuron proliferation_Prnp<tm2Lnq>/Prnp<tm2Lnq>
  http://metadb.riken.jp/0009967I129P2OlaHsdC57BL6NPrnptm2LnqPrnptm2LnqPrnptm2Lnq
• increased neuron apoptosis_Prnp<tm3Lnq>/Prnp<tm3Lnq>
  http://metadb.riken.jp/0003203I129P2OlaHsdC57BL6NPrnptm3LnqPrnptm3LnqPrnptm3Lnq
• abnormal sleep pattern_Prnp<tm2Lnq>/Prnp<tm2Lnq>
  http://metadb.riken.jp/0001501I129P2OlaHsdC57BL6NPrnptm2LnqPrnptm2LnqPrnptm2Lnq
• premature death_Prnp<tm3Lnq>/Prnp<tm3Lnq>
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6NPrnptm3LnqPrnptm3LnqPrnptm3Lnq
• abnormal hippocampus CA1 region morphology_Prnp<tm3Lnq>/Prnp<tm3Lnq>
  http://metadb.riken.jp/0008263I129P2OlaHsdC57BL6NPrnptm3LnqPrnptm3LnqPrnptm3Lnq
• neuron degeneration_Prnp<tm2Lnq>/Prnp<tm2Lnq>
  http://metadb.riken.jp/0003224I129P2OlaHsdC57BL6NPrnptm2LnqPrnptm2LnqPrnptm2Lnq
• abnormal neuron proliferation_Prnp<tm3Lnq>/Prnp<tm3Lnq>
  http://metadb.riken.jp/0009967I129P2OlaHsdC57BL6NPrnptm3LnqPrnptm3LnqPrnptm3Lnq
• abnormal retina morphology_Prnp<tm3Lnq>/Prnp<tm3Lnq>
  http://metadb.riken.jp/0001325I129P2OlaHsdC57BL6NPrnptm3LnqPrnptm3LnqPrnptm3Lnq
• abnormal cerebellar molecular layer_Prnp<tm3Lnq>/Prnp<tm3Lnq>
  http://metadb.riken.jp/0000889I129P2OlaHsdC57BL6NPrnptm3LnqPrnptm3LnqPrnptm3Lnq
• impaired coordination_Prnp<tm2Lnq>/Prnp<tm2Lnq>
  http://metadb.riken.jp/0001405I129P2OlaHsdC57BL6NPrnptm2LnqPrnptm2LnqPrnptm2Lnq
• spongiform encephalopathy_Prnp<tm3Lnq>/Prnp<tm3Lnq>
  http://metadb.riken.jp/0002654I129P2OlaHsdC57BL6NPrnptm3LnqPrnptm3LnqPrnptm3Lnq
• hypoactivity_Prnp<tm3Lnq>/Prnp<tm3Lnq>
  http://metadb.riken.jp/0001402I129P2OlaHsdC57BL6NPrnptm3LnqPrnptm3LnqPrnptm3Lnq
• impaired coordination_Prnp<tm3Lnq>/Prnp<tm3Lnq>
  http://metadb.riken.jp/0001405I129P2OlaHsdC57BL6NPrnptm3LnqPrnptm3LnqPrnptm3Lnq
• increased neuron apoptosis_Prnp<tm2Lnq>/Prnp<tm2Lnq>
  http://metadb.riken.jp/0003203I129P2OlaHsdC57BL6NPrnptm2LnqPrnptm2LnqPrnptm2Lnq
• abnormal olfactory bulb morphology_Prnp<tm3Lnq>/Prnp<tm3Lnq>
  http://metadb.riken.jp/0000819I129P2OlaHsdC57BL6NPrnptm3LnqPrnptm3LnqPrnptm3Lnq
• abnormal thalamus morphology_Prnp<tm2Lnq>/Prnp<tm2Lnq>
  http://metadb.riken.jp/0000832I129P2OlaHsdC57BL6NPrnptm2LnqPrnptm2LnqPrnptm2Lnq
• enlarged brain ventricles_Prnp<tm2Lnq>/Prnp<tm2Lnq>
  http://metadb.riken.jp/0011380I129P2OlaHsdC57BL6NPrnptm2LnqPrnptm2LnqPrnptm2Lnq
• abnormal hippocampus morphology_Prnp<tm3Lnq>/Prnp<tm3Lnq>
  http://metadb.riken.jp/0000807I129P2OlaHsdC57BL6NPrnptm3LnqPrnptm3LnqPrnptm3Lnq

class

http://purl.org/net/cito/citesAsAuthority

• Prnp<tm3Lnq>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5546407