Laura K. Fogli, et.al., T cell-derived IL-17 mediates epithelial changes in the airway and drives pulmonary neutrophilia., Journal of immunology (Baltimore, Md. : 1950), 2013, 191

http://rdf.ncbi.nlm.nih.gov/pubmed/23966625

Laura K. Fogli, et.al., T cell-derived IL-17 mediates epithelial changes in the airway and drives pulmonary neutrophilia., Journal of immunology (Baltimore, Md. : 1950), 2013, 191

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5557999

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased regulatory T cell number_Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>/Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0004973IC57BL6DBA2GtROSA26Sortm1Stat3SbkvGtROSA26Sortm1Stat3SbkvTgCd4cre1Cwi0GtROSA26Sortm1Stat3SbkvTgCd4cre1Cwi
• premature death_Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>/Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0002083IC57BL6DBA2GtROSA26Sortm1Stat3SbkvGtROSA26Sortm1Stat3SbkvTgCd4cre1Cwi0GtROSA26Sortm1Stat3SbkvTgCd4cre1Cwi
• decreased lung compliance_Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>/Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0010896IC57BL6DBA2GtROSA26Sortm1Stat3SbkvGtROSA26Sortm1Stat3SbkvTgCd4cre1Cwi0GtROSA26Sortm1Stat3SbkvTgCd4cre1Cwi
• increased lung elastance_Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>/Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0011044IC57BL6DBA2GtROSA26Sortm1Stat3SbkvGtROSA26Sortm1Stat3SbkvTgCd4cre1Cwi0GtROSA26Sortm1Stat3SbkvTgCd4cre1Cwi
• abnormal T-helper 17 cell differentiation_Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>/Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>
  http://metadb.riken.jp/0010221IC57BL6GtROSA26Sortm1Stat3SbkvGtROSA26Sortm1Stat3SbkvGtROSA26Sortm1Stat3Sbkv
• lung inflammation_Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>/Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0001861IC57BL6DBA2GtROSA26Sortm1Stat3SbkvGtROSA26Sortm1Stat3SbkvTgCd4cre1Cwi0GtROSA26Sortm1Stat3SbkvTgCd4cre1Cwi
• increased T-helper 1 cell number_Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>/Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008086IC57BL6DBA2GtROSA26Sortm1Stat3SbkvGtROSA26Sortm1Stat3SbkvTgCd4cre1Cwi0GtROSA26Sortm1Stat3SbkvTgCd4cre1Cwi
• increased T-helper 17 cell number_Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>/Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0010219IC57BL6DBA2GtROSA26Sortm1Stat3SbkvGtROSA26Sortm1Stat3SbkvTgCd4cre1Cwi0GtROSA26Sortm1Stat3SbkvTgCd4cre1Cwi
• increased interleukin-17 secretion_Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>/Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008681IC57BL6DBA2GtROSA26Sortm1Stat3SbkvGtROSA26Sortm1Stat3SbkvTgCd4cre1Cwi0GtROSA26Sortm1Stat3SbkvTgCd4cre1Cwi
• increased circulating interleukin-17 level_Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>/Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008614IC57BL6DBA2GtROSA26Sortm1Stat3SbkvGtROSA26Sortm1Stat3SbkvTgCd4cre1Cwi0GtROSA26Sortm1Stat3SbkvTgCd4cre1Cwi
• increased airway resistance_Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>/Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0010935IC57BL6DBA2GtROSA26Sortm1Stat3SbkvGtROSA26Sortm1Stat3SbkvTgCd4cre1Cwi0GtROSA26Sortm1Stat3SbkvTgCd4cre1Cwi

class

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(Stat3*)Sbkv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5557999