Hilde. Schjerven, et.al., Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros., Nature immunology, 2013, 14

http://rdf.ncbi.nlm.nih.gov/pubmed/24013668

Hilde. Schjerven, et.al., Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros., Nature immunology, 2013, 14

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ikzf1<tm1.1Smale>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5563075
• Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5563076

class

http://purl.org/net/cito/citesAsAuthority

• Ikzf1<tm1.1Smale>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5563075
• Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5563076

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• thymus cortex hypoplasia_Ikzf1<tm2.1Smale>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0000711B6CgIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21Smale
• decreased body size_Ikzf1<tm2.1Smale>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0001265B6CgIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21Smale
• thymus hypoplasia_Ikzf1<tm1.1Smale>/Ikzf1<tm1.1Smale>
  http://metadb.riken.jp/0001823B6CgIkzf1tm11SmaleIkzf1tm11SmaleIkzf1tm11SmaleIkzf1tm11Smale
• thymus hypoplasia_Ikzf1<tm2.1Smale>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0001823B6CgIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21Smale
• premature death_Ikzf1<tm2.1Smale>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0002083B6CgIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21Smale
• abnormal definitive hematopoiesis_Ikzf1<tm2.1Smale>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0002123B6CgIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21Smale
他31件を見る
• abnormal T cell differentiation_Ikzf1<tm2.1Smale>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0002145B6CgIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21Smale
• abnormal T cell differentiation_Ikzf1<tm2Kge>/Ikzf1<tm2Kge>
  http://metadb.riken.jp/0002145I129S4SvJaeIkzf1tm2KgeIkzf1tm2KgeIkzf1tm2Kge
• abnormal lymphopoiesis_Ikzf1<tm2.1Smale>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0002401B6CgIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21Smale
• absent Peyer's patches_Ikzf1<tm2.1Smale>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0002831B6CgIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21Smale
• increased pre-B cell number_Ikzf1<tm2.1Smale>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0003132B6CgIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21Smale
• decreased B cell number_Ikzf1<tm1.1Smale>/Ikzf1<tm1.1Smale>
  http://metadb.riken.jp/0005017B6CgIkzf1tm11SmaleIkzf1tm11SmaleIkzf1tm11SmaleIkzf1tm11Smale
• decreased B cell number_Ikzf1<tm2.1Smale>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0005017B6CgIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21Smale
• decreased double-negative T cell number_Ikzf1<tm2.1Smale>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0005089B6CgIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21Smale
• decreased double-positive T cell number_Ikzf1<tm2.1Smale>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0005092B6CgIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21Smale
• absent NK cells_Ikzf1<tm2.1Smale>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0008046B6CgIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21Smale
• absent NK cells_Ikzf1<tm2Kge>/Ikzf1<tm2Kge>
  http://metadb.riken.jp/0008046I129S4SvJaeIkzf1tm2KgeIkzf1tm2KgeIkzf1tm2Kge
• absent B cells_Ikzf1<tm2Kge>/Ikzf1<tm2Kge>
  http://metadb.riken.jp/0008071I129S4SvJaeIkzf1tm2KgeIkzf1tm2KgeIkzf1tm2Kge
• decreased plasmacytoid dendritic cell number_Ikzf1<tm2.1Smale>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0008124B6CgIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21Smale
• decreased plasmacytoid dendritic cell number_Ikzf1<tm2Kge>/Ikzf1<tm2Kge>
  http://metadb.riken.jp/0008124I129S4SvJaeIkzf1tm2KgeIkzf1tm2KgeIkzf1tm2Kge
• decreased B-1a cell number_Ikzf1<tm1.1Smale>/Ikzf1<tm1.1Smale>
  http://metadb.riken.jp/0008168B6CgIkzf1tm11SmaleIkzf1tm11SmaleIkzf1tm11SmaleIkzf1tm11Smale
• decreased B-1b cell number_Ikzf1<tm1.1Smale>/Ikzf1<tm1.1Smale>
  http://metadb.riken.jp/0008170B6CgIkzf1tm11SmaleIkzf1tm11SmaleIkzf1tm11SmaleIkzf1tm11Smale
• decreased pre-B cell number_Ikzf1<tm1.1Smale>/Ikzf1<tm1.1Smale>
  http://metadb.riken.jp/0008209B6CgIkzf1tm11SmaleIkzf1tm11SmaleIkzf1tm11SmaleIkzf1tm11Smale
• decreased mature B cell number_Ikzf1<tm1.1Smale>/Ikzf1<tm1.1Smale>
  http://metadb.riken.jp/0008211B6CgIkzf1tm11SmaleIkzf1tm11SmaleIkzf1tm11SmaleIkzf1tm11Smale
• decreased mature B cell number_Ikzf1<tm2.1Smale>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0008211B6CgIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21Smale
• decreased immature B cell number_Ikzf1<tm1.1Smale>/Ikzf1<tm1.1Smale>
  http://metadb.riken.jp/0008215B6CgIkzf1tm11SmaleIkzf1tm11SmaleIkzf1tm11SmaleIkzf1tm11Smale
• decreased immature B cell number_Ikzf1<tm2.1Smale>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0008215B6CgIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21Smale
• increased gamma-delta T cell number_Ikzf1<tm2.1Smale>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0008346B6CgIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21Smale
• abnormal peripheral lymph node morphology_Ikzf1<tm2.1Smale>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0008463B6CgIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21Smale
• absent inguinal lymph nodes_Ikzf1<tm2.1Smale>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0009622B6CgIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21Smale
• decreased DN1 thymic pro-T cell number_Ikzf1<tm1.1Smale>/Ikzf1<tm1.1Smale>
  http://metadb.riken.jp/0010130B6CgIkzf1tm11SmaleIkzf1tm11SmaleIkzf1tm11SmaleIkzf1tm11Smale
• decreased DN2 thymocyte number_Ikzf1<tm2.1Smale>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0010132B6CgIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21Smale
• decreased DN3 thymocyte number_Ikzf1<tm2.1Smale>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0010134B6CgIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21Smale
• lethality, complete penetrance_Ikzf1<tm1.1Smale>/Ikzf1<tm2Kge>
  http://metadb.riken.jp/0011400I129S4SvJaeC57BL6Ikzf1tm11SmaleIkzf1tm2KgeIkzf1tm11SmaleIkzf1tm2Kge
• lethality, complete penetrance_Ikzf1<tm2Kge>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0011400I129S4SvJaeC57BL6Ikzf1tm2KgeIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm2Kge
• decreased pre-pro B cell number_Ikzf1<tm2.1Smale>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0011816B6CgIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21Smale
• increased lymphoma incidence_Ikzf1<tm2.1Smale>/Ikzf1<tm2.1Smale>
  http://metadb.riken.jp/0012431B6CgIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21SmaleIkzf1tm21Smale