Sara Koenig. McLaughlin, et.al., The RasGAP gene, RASAL2, is a tumor and metastasis suppressor., Cancer cell, 2013, 24

http://rdf.ncbi.nlm.nih.gov/pubmed/24029233

Sara Koenig. McLaughlin, et.al., The RasGAP gene, RASAL2, is a tumor and metastasis suppressor., Cancer cell, 2013, 24

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• premature death_Rasal2<Gt(463C12)Cmhd>/Rasal2<Gt(463C12)Cmhd>
  http://metadb.riken.jp/0002083I129S1Sv129X1SvJC57BL6NCrlRasal2Gt463C12CmhdRasal2Gt463C12CmhdRasal2Gt463C12Cmhd
• increased hepatocellular carcinoma incidence_Rasal2<Gt(463C12)Cmhd>/Rasal2<Gt(463C12)Cmhd>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0003331I129S129X1SvJC57BL6C57BL6NCrlRasal2Gt463C12CmhdRasal2Gt463C12CmhdTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjRasal2Gt463C12Cmhd
• increased colonic adenoma incidence_Rasal2<Gt(463C12)Cmhd>/Rasal2<Gt(463C12)Cmhd>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0002044I129S129X1SvJC57BL6C57BL6NCrlRasal2Gt463C12CmhdRasal2Gt463C12CmhdTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjRasal2Gt463C12Cmhd
• increased metastatic potential_Rasal2<Gt(463C12)Cmhd>/Rasal2<Gt(463C12)Cmhd>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0001272I129S129X1SvJC57BL6C57BL6NCrlRasal2Gt463C12CmhdRasal2Gt463C12CmhdTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjRasal2Gt463C12Cmhd
• increased mouth tumor incidence_Rasal2<Gt(463C12)Cmhd>/Rasal2<Gt(463C12)Cmhd>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0003750I129S129X1SvJC57BL6C57BL6NCrlRasal2Gt463C12CmhdRasal2Gt463C12CmhdTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjRasal2Gt463C12Cmhd
• decreased tumor latency_Rasal2<Gt(463C12)Cmhd>/Rasal2<Gt(463C12)Cmhd>
  http://metadb.riken.jp/0010308I129S1Sv129X1SvJC57BL6NCrlRasal2Gt463C12CmhdRasal2Gt463C12CmhdRasal2Gt463C12Cmhd
• increased stomach tumor incidence_Rasal2<Gt(463C12)Cmhd>/Rasal2<Gt(463C12)Cmhd>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0010301I129S129X1SvJC57BL6C57BL6NCrlRasal2Gt463C12CmhdRasal2Gt463C12CmhdTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjRasal2Gt463C12Cmhd
• increased metastatic potential_Rasal2<Gt(463C12)Cmhd>/Rasal2<Gt(463C12)Cmhd>,Tg(MMTVneu)202Mul/0
  http://metadb.riken.jp/0001272I129S1Sv129X1SvJC57BL6NCrlFVBNRasal2Gt463C12CmhdRasal2Gt463C12CmhdTgMMTVneu202Mul0TgMMTVneu202MulRasal2Gt463C12Cmhd
• increased lymphoma incidence_Rasal2<Gt(463C12)Cmhd>/Rasal2<Gt(463C12)Cmhd>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0012431I129S129X1SvJC57BL6C57BL6NCrlRasal2Gt463C12CmhdRasal2Gt463C12CmhdTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjRasal2Gt463C12Cmhd
• increased mammary adenocarcinoma incidence_Rasal2<Gt(463C12)Cmhd>/Rasal2<Gt(463C12)Cmhd>,Tg(MMTVneu)202Mul/0
  http://metadb.riken.jp/0001883I129S1Sv129X1SvJC57BL6NCrlFVBNRasal2Gt463C12CmhdRasal2Gt463C12CmhdTgMMTVneu202Mul0TgMMTVneu202MulRasal2Gt463C12Cmhd
• premature death_Rasal2<Gt(463C12)Cmhd>/Rasal2<Gt(463C12)Cmhd>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0002083I129S129X1SvJC57BL6C57BL6NCrlRasal2Gt463C12CmhdRasal2Gt463C12CmhdTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjRasal2Gt463C12Cmhd
• increased metastatic potential_Rasal2<Gt(463C12)Cmhd>/Rasal2<+>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0001272I129S129X1SvJC57BL6C57BL6NCrlRasal2Gt463C12CmhdRasal2Trp53tm1TyjTrp53tm1TyjTrp53tm1TyjRasal2Rasal2Gt463C12Cmhd
• increased liver tumor incidence_Rasal2<Gt(463C12)Cmhd>/Rasal2<Gt(463C12)Cmhd>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0008019I129S129X1SvJC57BL6C57BL6NCrlRasal2Gt463C12CmhdRasal2Gt463C12CmhdTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjRasal2Gt463C12Cmhd