Eva M. Briso, et.al., Inflammation-mediated skin tumorigenesis induced by epidermal c-Fos., Genes & development, 2013, 27

http://rdf.ncbi.nlm.nih.gov/pubmed/24029918

Eva M. Briso, et.al., Inflammation-mediated skin tumorigenesis induced by epidermal c-Fos., Genes & development, 2013, 27

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Col1a1<tm1(tetO-Fos)Wag>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5555845

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased papilloma incidence_Col1a1<tm1(tetO-Fos)Wag>/Col1a1<+>,Tg(KRT5-rtTA)T2D6Sgkd/0
  http://metadb.riken.jp/0002014I129S4SvJaeC57BL6FVBNCol1a1tm1tetOFosWagCol1a1TgKRT5rtTAT2D6Sgkd0Col1a1Col1a1tm1tetOFosWagTgKRT5rtTAT2D6Sgkd
• epidermal hyperplasia_Col1a1<tm1(tetO-Fos)Wag>/Col1a1<+>,Tg(KRT5-rtTA)T2D6Sgkd/0
  http://metadb.riken.jp/0001222I129S4SvJaeC57BL6FVBNCol1a1tm1tetOFosWagCol1a1TgKRT5rtTAT2D6Sgkd0Col1a1Col1a1tm1tetOFosWagTgKRT5rtTAT2D6Sgkd
• hyperkeratosis_Col1a1<tm1(tetO-Fos)Wag>/Col1a1<+>,Tg(KRT5-rtTA)T2D6Sgkd/0
  http://metadb.riken.jp/0001242I129S4SvJaeC57BL6FVBNCol1a1tm1tetOFosWagCol1a1TgKRT5rtTAT2D6Sgkd0Col1a1Col1a1tm1tetOFosWagTgKRT5rtTAT2D6Sgkd
• thick skin_Col1a1<tm1(tetO-Fos)Wag>/Col1a1<+>,Tg(KRT5-rtTA)T2D6Sgkd/0
  http://metadb.riken.jp/0001200I129S4SvJaeC57BL6FVBNCol1a1tm1tetOFosWagCol1a1TgKRT5rtTAT2D6Sgkd0Col1a1Col1a1tm1tetOFosWagTgKRT5rtTAT2D6Sgkd
• skin hyperplasia_Col1a1<tm1(tetO-Fos)Wag>/Col1a1<+>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(KRT5-rtTA)T2D6Sgkd/0
  http://metadb.riken.jp/0001214I129S4SvJae129S7SvEvBrdC57BL6FVBNCol1a1tm1tetOFosWagCol1a1Rag1tm1MomRag1tm1MomTgKRT5rtTAT2D6Sgkd0TgKRT5rtTAT2D6SgkdRag1tm1MomCol1a1tm1tetOFosWagCol1a1
• abnormal forestomach morphology_Col1a1<tm1(tetO-Fos)Wag>/Col1a1<+>,Tg(KRT5-rtTA)T2D6Sgkd/0
  http://metadb.riken.jp/0010784I129S4SvJaeC57BL6FVBNCol1a1tm1tetOFosWagCol1a1TgKRT5rtTAT2D6Sgkd0Col1a1Col1a1tm1tetOFosWagTgKRT5rtTAT2D6Sgkd
• skin hyperplasia_Col1a1<tm1(tetO-Fos)Wag>/Col1a1<+>,Tg(KRT5-rtTA)T2D6Sgkd/0
  http://metadb.riken.jp/0001214I129S4SvJaeC57BL6FVBNCol1a1tm1tetOFosWagCol1a1TgKRT5rtTAT2D6Sgkd0Col1a1Col1a1tm1tetOFosWagTgKRT5rtTAT2D6Sgkd
• skin lesions_Col1a1<tm1(tetO-Fos)Wag>/Col1a1<+>,Tg(KRT5-rtTA)T2D6Sgkd/0
  http://metadb.riken.jp/0001212I129S4SvJaeC57BL6FVBNCol1a1tm1tetOFosWagCol1a1TgKRT5rtTAT2D6Sgkd0Col1a1Col1a1tm1tetOFosWagTgKRT5rtTAT2D6Sgkd
• increased incidence of tumors by chemical induction_Col1a1<tm1(tetO-Fos)Wag>/Col1a1<+>,Tg(KRT5-rtTA)T2D6Sgkd/0
  http://metadb.riken.jp/0004499I129S4SvJaeC57BL6FVBNCol1a1tm1tetOFosWagCol1a1TgKRT5rtTAT2D6Sgkd0Col1a1Col1a1tm1tetOFosWagTgKRT5rtTAT2D6Sgkd
• premature death_Col1a1<tm1(tetO-Fos)Wag>/Col1a1<+>,Tg(KRT5-rtTA)T2D6Sgkd/0
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6FVBNCol1a1tm1tetOFosWagCol1a1TgKRT5rtTAT2D6Sgkd0Col1a1Col1a1tm1tetOFosWagTgKRT5rtTAT2D6Sgkd
• increased CD4-positive, alpha beta T cell number_Col1a1<tm1(tetO-Fos)Wag>/Col1a1<+>,Tg(KRT5-rtTA)T2D6Sgkd/0
  http://metadb.riken.jp/0008074I129S4SvJaeC57BL6FVBNCol1a1tm1tetOFosWagCol1a1TgKRT5rtTAT2D6Sgkd0Col1a1Col1a1tm1tetOFosWagTgKRT5rtTAT2D6Sgkd
• decreased body size_Col1a1<tm1(tetO-Fos)Wag>/Col1a1<+>,Tg(KRT5-rtTA)T2D6Sgkd/0
  http://metadb.riken.jp/0001265I129S4SvJaeC57BL6FVBNCol1a1tm1tetOFosWagCol1a1TgKRT5rtTAT2D6Sgkd0Col1a1Col1a1tm1tetOFosWagTgKRT5rtTAT2D6Sgkd
• increased granulocyte number_Col1a1<tm1(tetO-Fos)Wag>/Col1a1<+>,Tg(KRT5-rtTA)T2D6Sgkd/0
  http://metadb.riken.jp/0000322I129S4SvJaeC57BL6FVBNCol1a1tm1tetOFosWagCol1a1TgKRT5rtTAT2D6Sgkd0Col1a1Col1a1tm1tetOFosWagTgKRT5rtTAT2D6Sgkd
• parakeratosis_Col1a1<tm1(tetO-Fos)Wag>/Col1a1<+>,Tg(KRT5-rtTA)T2D6Sgkd/0
  http://metadb.riken.jp/0003427I129S4SvJaeC57BL6FVBNCol1a1tm1tetOFosWagCol1a1TgKRT5rtTAT2D6Sgkd0Col1a1Col1a1tm1tetOFosWagTgKRT5rtTAT2D6Sgkd
• absent hair follicles_Col1a1<tm1(tetO-Fos)Wag>/Col1a1<+>,Tg(KRT5-rtTA)T2D6Sgkd/0
  http://metadb.riken.jp/0000378I129S4SvJaeC57BL6FVBNCol1a1tm1tetOFosWagCol1a1TgKRT5rtTAT2D6Sgkd0Col1a1Col1a1tm1tetOFosWagTgKRT5rtTAT2D6Sgkd
• skin inflammation_Col1a1<tm1(tetO-Fos)Wag>/Col1a1<+>,Tg(KRT5-rtTA)T2D6Sgkd/0
  http://metadb.riken.jp/0004947I129S4SvJaeC57BL6FVBNCol1a1tm1tetOFosWagCol1a1TgKRT5rtTAT2D6Sgkd0Col1a1Col1a1tm1tetOFosWagTgKRT5rtTAT2D6Sgkd
• skin lesions_Col1a1<tm1(tetO-Fos)Wag>/Col1a1<+>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(KRT5-rtTA)T2D6Sgkd/0
  http://metadb.riken.jp/0001212I129S4SvJae129S7SvEvBrdC57BL6FVBNCol1a1tm1tetOFosWagCol1a1Rag1tm1MomRag1tm1MomTgKRT5rtTAT2D6Sgkd0TgKRT5rtTAT2D6SgkdRag1tm1MomCol1a1tm1tetOFosWagCol1a1
• increased keratinocyte proliferation_Col1a1<tm1(tetO-Fos)Wag>/Col1a1<+>,Tg(KRT5-rtTA)T2D6Sgkd/0
  http://metadb.riken.jp/0009583I129S4SvJaeC57BL6FVBNCol1a1tm1tetOFosWagCol1a1TgKRT5rtTAT2D6Sgkd0Col1a1Col1a1tm1tetOFosWagTgKRT5rtTAT2D6Sgkd
• alopecia_Col1a1<tm1(tetO-Fos)Wag>/Col1a1<+>,Tg(KRT5-rtTA)T2D6Sgkd/0
  http://metadb.riken.jp/0000414I129S4SvJaeC57BL6FVBNCol1a1tm1tetOFosWagCol1a1TgKRT5rtTAT2D6Sgkd0Col1a1Col1a1tm1tetOFosWagTgKRT5rtTAT2D6Sgkd

class

http://purl.org/net/cito/citesAsAuthority

• Col1a1<tm1(tetO-Fos)Wag>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5555845