Aline. Bozec, et.al., Osteoblast-specific expression of Fra-2/AP-1 controls adiponectin and osteocalcin expression and affects metabolism., Journal of cell science, 2013, 126

http://rdf.ncbi.nlm.nih.gov/pubmed/24046454

Aline. Bozec, et.al., Osteoblast-specific expression of Fra-2/AP-1 controls adiponectin and osteocalcin expression and affects metabolism., Journal of cell science, 2013, 126

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Col1a1<tm2(tetO-Fosl2,-DsRed)Wag>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5585642

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased bone volume_Col1a1<tm2(tetO-Fosl2,-DsRed)Wag>/Col1a1<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0010875I129S4SvJaeC57BL6CD1Col1a1tm2tetOFosl2DsRedWagCol1a1TgSp7tTAtetOEGFPcre1Amc0Col1a1Col1a1tm2tetOFosl2DsRedWagTgSp7tTAtetOEGFPcre1Amc
• increased insulin sensitivity_Col1a1<tm2(tetO-Fosl2,-DsRed)Wag>/Col1a1<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0002891I129S4SvJaeC57BL6CD1Col1a1tm2tetOFosl2DsRedWagCol1a1TgSp7tTAtetOEGFPcre1Amc0Col1a1Col1a1tm2tetOFosl2DsRedWagTgSp7tTAtetOEGFPcre1Amc
• decreased circulating glucose level_Col1a1<tm2(tetO-Fosl2,-DsRed)Wag>/Col1a1<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0005560I129S4SvJaeC57BL6CD1Col1a1tm2tetOFosl2DsRedWagCol1a1TgSp7tTAtetOEGFPcre1Amc0Col1a1Col1a1tm2tetOFosl2DsRedWagTgSp7tTAtetOEGFPcre1Amc
• increased bone trabecula number_Col1a1<tm2(tetO-Fosl2,-DsRed)Wag>/Col1a1<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0010868I129S4SvJaeC57BL6CD1Col1a1tm2tetOFosl2DsRedWagCol1a1TgSp7tTAtetOEGFPcre1Amc0Col1a1Col1a1tm2tetOFosl2DsRedWagTgSp7tTAtetOEGFPcre1Amc
• insulin resistance_Fosl2<tm2Wag>/Fosl2<tm2Wag>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0005331I129P2OlaHsdC57BL6CD1Fosl2tm2WagFosl2tm2WagTgSp7tTAtetOEGFPcre1Amc0TgSp7tTAtetOEGFPcre1AmcFosl2tm2Wag
• decreased adiponectin level_Col1a1<tm2(tetO-Fosl2,-DsRed)Wag>/Col1a1<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0004893I129S4SvJaeC57BL6CD1Col1a1tm2tetOFosl2DsRedWagCol1a1TgSp7tTAtetOEGFPcre1Amc0Col1a1Col1a1tm2tetOFosl2DsRedWagTgSp7tTAtetOEGFPcre1Amc
• improved glucose tolerance_Col1a1<tm2(tetO-Fosl2,-DsRed)Wag>/Col1a1<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0005292I129S4SvJaeC57BL6CD1Col1a1tm2tetOFosl2DsRedWagCol1a1TgSp7tTAtetOEGFPcre1Amc0Col1a1Col1a1tm2tetOFosl2DsRedWagTgSp7tTAtetOEGFPcre1Amc
• increased trabecular bone thickness_Col1a1<tm2(tetO-Fosl2,-DsRed)Wag>/Col1a1<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0009347I129S4SvJaeC57BL6CD1Col1a1tm2tetOFosl2DsRedWagCol1a1TgSp7tTAtetOEGFPcre1Amc0Col1a1Col1a1tm2tetOFosl2DsRedWagTgSp7tTAtetOEGFPcre1Amc
• decreased bone ossification_Fosl2<tm2Wag>/Fosl2<tm2Wag>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0020040I129P2OlaHsdC57BL6CD1Fosl2tm2WagFosl2tm2WagTgSp7tTAtetOEGFPcre1Amc0TgSp7tTAtetOEGFPcre1AmcFosl2tm2Wag
• abnormal circulating osteocalcin level_Fosl2<tm2Wag>/Fosl2<tm2Wag>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0011922I129P2OlaHsdC57BL6CD1Fosl2tm2WagFosl2tm2WagTgSp7tTAtetOEGFPcre1Amc0TgSp7tTAtetOEGFPcre1AmcFosl2tm2Wag
• abnormal osteoblast morphology_Col1a1<tm2(tetO-Fosl2,-DsRed)Wag>/Col1a1<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0004986I129S4SvJaeC57BL6CD1Col1a1tm2tetOFosl2DsRedWagCol1a1TgSp7tTAtetOEGFPcre1Amc0Col1a1Col1a1tm2tetOFosl2DsRedWagTgSp7tTAtetOEGFPcre1Amc
• abnormal osteoblast morphology_Fosl2<tm2Wag>/Fosl2<tm2Wag>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0004986I129P2OlaHsdC57BL6CD1Fosl2tm2WagFosl2tm2WagTgSp7tTAtetOEGFPcre1Amc0TgSp7tTAtetOEGFPcre1AmcFosl2tm2Wag
• abnormal osteoblast physiology_Col1a1<tm2(tetO-Fosl2,-DsRed)Wag>/Col1a1<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0005006I129S4SvJaeC57BL6CD1Col1a1tm2tetOFosl2DsRedWagCol1a1TgSp7tTAtetOEGFPcre1Amc0Col1a1Col1a1tm2tetOFosl2DsRedWagTgSp7tTAtetOEGFPcre1Amc
• abnormal osteoclast morphology_Fosl2<tm2Wag>/Fosl2<tm2Wag>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0004982I129P2OlaHsdC57BL6CD1Fosl2tm2WagFosl2tm2WagTgSp7tTAtetOEGFPcre1Amc0TgSp7tTAtetOEGFPcre1AmcFosl2tm2Wag
• decreased trabecular bone thickness_Fosl2<tm2Wag>/Fosl2<tm2Wag>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0009346I129P2OlaHsdC57BL6CD1Fosl2tm2WagFosl2tm2WagTgSp7tTAtetOEGFPcre1Amc0TgSp7tTAtetOEGFPcre1AmcFosl2tm2Wag
• decreased gonadal fat pad weight_Col1a1<tm2(tetO-Fosl2,-DsRed)Wag>/Col1a1<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0009283I129S4SvJaeC57BL6CD1Col1a1tm2tetOFosl2DsRedWagCol1a1TgSp7tTAtetOEGFPcre1Amc0Col1a1Col1a1tm2tetOFosl2DsRedWagTgSp7tTAtetOEGFPcre1Amc
• increased bone ossification_Col1a1<tm2(tetO-Fosl2,-DsRed)Wag>/Col1a1<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0020039I129S4SvJaeC57BL6CD1Col1a1tm2tetOFosl2DsRedWagCol1a1TgSp7tTAtetOEGFPcre1Amc0Col1a1Col1a1tm2tetOFosl2DsRedWagTgSp7tTAtetOEGFPcre1Amc
• impaired glucose tolerance_Fosl2<tm2Wag>/Fosl2<tm2Wag>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0005293I129P2OlaHsdC57BL6CD1Fosl2tm2WagFosl2tm2WagTgSp7tTAtetOEGFPcre1Amc0TgSp7tTAtetOEGFPcre1AmcFosl2tm2Wag
• increased body weight_Fosl2<tm2Wag>/Fosl2<tm2Wag>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0001260I129P2OlaHsdC57BL6CD1Fosl2tm2WagFosl2tm2WagTgSp7tTAtetOEGFPcre1Amc0TgSp7tTAtetOEGFPcre1AmcFosl2tm2Wag
• abnormal osteoblast physiology_Fosl2<tm2Wag>/Fosl2<tm2Wag>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0005006I129P2OlaHsdC57BL6CD1Fosl2tm2WagFosl2tm2WagTgSp7tTAtetOEGFPcre1Amc0TgSp7tTAtetOEGFPcre1AmcFosl2tm2Wag
• abnormal osteoclast morphology_Col1a1<tm2(tetO-Fosl2,-DsRed)Wag>/Col1a1<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0004982I129S4SvJaeC57BL6CD1Col1a1tm2tetOFosl2DsRedWagCol1a1TgSp7tTAtetOEGFPcre1Amc0Col1a1Col1a1tm2tetOFosl2DsRedWagTgSp7tTAtetOEGFPcre1Amc
• decreased circulating glucose level_Fosl2<tm2Wag>/Fosl2<tm2Wag>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0005560I129P2OlaHsdC57BL6CD1Fosl2tm2WagFosl2tm2WagTgSp7tTAtetOEGFPcre1Amc0TgSp7tTAtetOEGFPcre1AmcFosl2tm2Wag
• increased gonadal fat pad weight_Fosl2<tm2Wag>/Fosl2<tm2Wag>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0009285I129P2OlaHsdC57BL6CD1Fosl2tm2WagFosl2tm2WagTgSp7tTAtetOEGFPcre1Amc0TgSp7tTAtetOEGFPcre1AmcFosl2tm2Wag
• decreased body weight_Col1a1<tm2(tetO-Fosl2,-DsRed)Wag>/Col1a1<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0001262I129S4SvJaeC57BL6CD1Col1a1tm2tetOFosl2DsRedWagCol1a1TgSp7tTAtetOEGFPcre1Amc0Col1a1Col1a1tm2tetOFosl2DsRedWagTgSp7tTAtetOEGFPcre1Amc
• decreased insulin secretion_Col1a1<tm2(tetO-Fosl2,-DsRed)Wag>/Col1a1<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0003059I129S4SvJaeC57BL6CD1Col1a1tm2tetOFosl2DsRedWagCol1a1TgSp7tTAtetOEGFPcre1Amc0Col1a1Col1a1tm2tetOFosl2DsRedWagTgSp7tTAtetOEGFPcre1Amc
• abnormal circulating osteocalcin level_Col1a1<tm2(tetO-Fosl2,-DsRed)Wag>/Col1a1<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0011922I129S4SvJaeC57BL6CD1Col1a1tm2tetOFosl2DsRedWagCol1a1TgSp7tTAtetOEGFPcre1Amc0Col1a1Col1a1tm2tetOFosl2DsRedWagTgSp7tTAtetOEGFPcre1Amc
• decreased bone volume_Fosl2<tm2Wag>/Fosl2<tm2Wag>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0010876I129P2OlaHsdC57BL6CD1Fosl2tm2WagFosl2tm2WagTgSp7tTAtetOEGFPcre1Amc0TgSp7tTAtetOEGFPcre1AmcFosl2tm2Wag
• decreased circulating insulin level_Col1a1<tm2(tetO-Fosl2,-DsRed)Wag>/Col1a1<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0002727I129S4SvJaeC57BL6CD1Col1a1tm2tetOFosl2DsRedWagCol1a1TgSp7tTAtetOEGFPcre1Amc0Col1a1Col1a1tm2tetOFosl2DsRedWagTgSp7tTAtetOEGFPcre1Amc
• decreased bone trabecula number_Fosl2<tm2Wag>/Fosl2<tm2Wag>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0010869I129P2OlaHsdC57BL6CD1Fosl2tm2WagFosl2tm2WagTgSp7tTAtetOEGFPcre1Amc0TgSp7tTAtetOEGFPcre1AmcFosl2tm2Wag

class

http://purl.org/net/cito/citesAsAuthority

• Col1a1<tm2(tetO-Fosl2,-DsRed)Wag>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5585642