Robert C. Lyon, et.al., Connexin defects underlie arrhythmogenic right ventricular cardiomyopathy in a novel mouse model., Human molecular genetics, 2014, 23

http://rdf.ncbi.nlm.nih.gov/pubmed/24108106

Robert C. Lyon, et.al., Connexin defects underlie arrhythmogenic right ventricular cardiomyopathy in a novel mouse model., Human molecular genetics, 2014, 23

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal heart morphology_Dsp<tm1Efu>/Dsp<tm1Efu>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0000266I129129S4SvJaeC57BL6Dsptm1EfuDsptm1EfuMyl2tm1creKrcMyl2Dsptm1EfuMyl2Myl2tm1creKrc
• enlarged heart_Dsp<tm1Efu>/Dsp<tm1Efu>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0000274I129129S4SvJaeC57BL6Dsptm1EfuDsptm1EfuMyl2tm1creKrcMyl2Dsptm1EfuMyl2Myl2tm1creKrc
• abnormal myocardial fiber morphology_Dsp<tm1Efu>/Dsp<tm1Efu>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0000278I129129S4SvJaeC57BL6Dsptm1EfuDsptm1EfuMyl2tm1creKrcMyl2Dsptm1EfuMyl2Myl2tm1creKrc
• irregular heartbeat_Dsp<tm1Efu>/Dsp<tm1Efu>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0001636I129129S4SvJaeC57BL6Dsptm1EfuDsptm1EfuMyl2tm1creKrcMyl2Dsptm1EfuMyl2Myl2tm1creKrc
• premature death_Dsp<tm1Efu>/Dsp<tm1Efu>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0002083I129129S4SvJaeC57BL6Dsptm1EfuDsptm1EfuMyl2tm1creKrcMyl2Dsptm1EfuMyl2Myl2tm1creKrc
• ventricular cardiomyopathy_Dsp<tm1Efu>/Dsp<tm1Efu>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0002952I129129S4SvJaeC57BL6Dsptm1EfuDsptm1EfuMyl2tm1creKrcMyl2Dsptm1EfuMyl2Myl2tm1creKrc
他14件を見る
• abnormal impulse conducting system conduction_Dsp<tm1Efu>/Dsp<tm1Efu>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0003137I129129S4SvJaeC57BL6Dsptm1EfuDsptm1EfuMyl2tm1creKrcMyl2Dsptm1EfuMyl2Myl2tm1creKrc
• cardiac fibrosis_Dsp<tm1Efu>/Dsp<tm1Efu>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0003141I129129S4SvJaeC57BL6Dsptm1EfuDsptm1EfuMyl2tm1creKrcMyl2Dsptm1EfuMyl2Myl2tm1creKrc
• abnormal Z lines_Dsp<tm1Efu>/Dsp<tm1Efu>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0004091I129129S4SvJaeC57BL6Dsptm1EfuDsptm1EfuMyl2tm1creKrcMyl2Dsptm1EfuMyl2Myl2tm1creKrc
• abnormal myocardium layer morphology_Dsp<tm1Efu>/Dsp<tm1Efu>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0005329I129129S4SvJaeC57BL6Dsptm1EfuDsptm1EfuMyl2tm1creKrcMyl2Dsptm1EfuMyl2Myl2tm1creKrc
• decreased ventricle muscle contractility_Dsp<tm1Efu>/Dsp<tm1Efu>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0005598I129129S4SvJaeC57BL6Dsptm1EfuDsptm1EfuMyl2tm1creKrcMyl2Dsptm1EfuMyl2Myl2tm1creKrc
• increased apoptosis_Dsp<tm1Efu>/Dsp<tm1Efu>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0006042I129129S4SvJaeC57BL6Dsptm1EfuDsptm1EfuMyl2tm1creKrcMyl2Dsptm1EfuMyl2Myl2tm1creKrc
• abnormal intercalated disc morphology_Dsp<tm1Efu>/Dsp<tm1Efu>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0006267I129129S4SvJaeC57BL6Dsptm1EfuDsptm1EfuMyl2tm1creKrcMyl2Dsptm1EfuMyl2Myl2tm1creKrc
• dilated heart ventricle_Dsp<tm1Efu>/Dsp<tm1Efu>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0008022I129129S4SvJaeC57BL6Dsptm1EfuDsptm1EfuMyl2tm1creKrcMyl2Dsptm1EfuMyl2Myl2tm1creKrc
• enlarged heart atrium_Dsp<tm1Efu>/Dsp<tm1Efu>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0008725I129129S4SvJaeC57BL6Dsptm1EfuDsptm1EfuMyl2tm1creKrcMyl2Dsptm1EfuMyl2Myl2tm1creKrc
• ventricular premature beat_Dsp<tm1Efu>/Dsp<tm1Efu>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0009732I129129S4SvJaeC57BL6Dsptm1EfuDsptm1EfuMyl2tm1creKrcMyl2Dsptm1EfuMyl2Myl2tm1creKrc
• increased sensitivity to induced morbidity/mortality_Dsp<tm1Efu>/Dsp<tm1Efu>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0009763I129129S4SvJaeC57BL6Dsptm1EfuDsptm1EfuMyl2tm1creKrcMyl2Dsptm1EfuMyl2Myl2tm1creKrc
• prolonged QRS complex duration_Dsp<tm1Efu>/Dsp<tm1Efu>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0010392I129129S4SvJaeC57BL6Dsptm1EfuDsptm1EfuMyl2tm1creKrcMyl2Dsptm1EfuMyl2Myl2tm1creKrc
• abnormal subendocardium layer morphology_Dsp<tm1Efu>/Dsp<tm1Efu>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0010546I129129S4SvJaeC57BL6Dsptm1EfuDsptm1EfuMyl2tm1creKrcMyl2Dsptm1EfuMyl2Myl2tm1creKrc
• bundle branch block_Dsp<tm1Efu>/Dsp<tm1Efu>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0010636I129129S4SvJaeC57BL6Dsptm1EfuDsptm1EfuMyl2tm1creKrcMyl2Dsptm1EfuMyl2Myl2tm1creKrc