Jean-Baptiste. Vannier, et.al., RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication., Science (New York, N.Y.), 2013, 342

http://rdf.ncbi.nlm.nih.gov/pubmed/24115439

Jean-Baptiste. Vannier, et.al., RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication., Science (New York, N.Y.), 2013, 342

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Rtel1<tm3.1Hdin>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5559531
• Rtel1<tm2.1Hdin>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5559530

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal mitosis_Rtel1<tm2.1Hdin>/Rtel1<tm2.1Hdin>
  http://metadb.riken.jp/0004046I129S1Sv129X1SvJC57BL6Rtel1tm21HdinRtel1tm21HdinRtel1tm21Hdin
• increased teratoma incidence_Rtel1<tm2.1Hdin>/Rtel1<tm2.1Hdin>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0002627I129S1Sv129S2SvPas129X1SvJC57BL6Rtel1tm21HdinRtel1tm21HdinTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjRtel1tm21Hdin
• abnormal DNA replication_Rtel1<tm1Hdin>/Rtel1<tm1Hdin>
  http://metadb.riken.jp/0008057I129S1Sv129X1SvJRtel1tm1HdinRtel1tm1HdinRtel1tm1Hdin
• abnormal telomere morphology_Rtel1<tm2.1Hdin>/Rtel1<tm2.1Hdin>
  http://metadb.riken.jp/0010207I129S1Sv129X1SvJC57BL6Rtel1tm21HdinRtel1tm21HdinRtel1tm21Hdin
• decreased tumor latency_Rtel1<tm2.1Hdin>/Rtel1<tm2.1Hdin>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0010308I129S1Sv129S2SvPas129X1SvJC57BL6Rtel1tm21HdinRtel1tm21HdinTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjRtel1tm21Hdin
• increased sarcoma incidence_Rtel1<tm2.1Hdin>/Rtel1<tm2.1Hdin>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0002032I129S1Sv129S2SvPas129X1SvJC57BL6Rtel1tm21HdinRtel1tm21HdinTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjRtel1tm21Hdin
• increased medulloblastoma incidence_Rtel1<tm2.1Hdin>/Rtel1<tm2.1Hdin>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0006283I129S1Sv129S2SvPas129X1SvJC57BL6Rtel1tm21HdinRtel1tm21HdinTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjRtel1tm21Hdin
• early cellular replicative senescence_Rtel1<tm2.1Hdin>/Rtel1<tm2.1Hdin>
  http://metadb.riken.jp/0008008I129S1Sv129X1SvJC57BL6Rtel1tm21HdinRtel1tm21HdinRtel1tm21Hdin
• abnormal telomere morphology_Rtel1<tm2.1Hdin>/Rtel1<tm2.1Hdin>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0010207I129S1Sv129S2SvPas129X1SvJC57BL6Rtel1tm21HdinRtel1tm21HdinTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjRtel1tm21Hdin
• increased lymphoma incidence_Rtel1<tm2.1Hdin>/Rtel1<tm2.1Hdin>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0012431I129S1Sv129S2SvPas129X1SvJC57BL6Rtel1tm21HdinRtel1tm21HdinTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjRtel1tm21Hdin
• abnormal DNA replication_Rtel1<tm2.1Hdin>/Rtel1<tm2.1Hdin>
  http://metadb.riken.jp/0008057I129S1Sv129X1SvJC57BL6Rtel1tm21HdinRtel1tm21HdinRtel1tm21Hdin
• abnormal cell physiology_Rtel1<tm2.1Hdin>/Rtel1<tm2.1Hdin>
  http://metadb.riken.jp/0005621I129S1Sv129X1SvJC57BL6Rtel1tm21HdinRtel1tm21HdinRtel1tm21Hdin
• premature death_Rtel1<tm2.1Hdin>/Rtel1<tm2.1Hdin>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0002083I129S1Sv129S2SvPas129X1SvJC57BL6Rtel1tm21HdinRtel1tm21HdinTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjRtel1tm21Hdin

class

http://purl.org/net/cito/citesAsAuthority

• Rtel1<tm3.1Hdin>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5559531
• Rtel1<tm2.1Hdin>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5559530