Vagelis. Rinotas, et.al., Novel genetic models of osteoporosis by overexpression of human RANKL in transgenic mice., Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2014, 29

http://rdf.ncbi.nlm.nih.gov/pubmed/24127173

Vagelis. Rinotas, et.al., Novel genetic models of osteoporosis by overexpression of human RANKL in transgenic mice., Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2014, 29

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(TNFSF11)5516Edou
  http://metadb.riken.jp/db/mgi_rdf/MGI:5788418
• Tg(TNFSF11)5519Edou
  http://metadb.riken.jp/db/mgi_rdf/MGI:5788420

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• osteoporosis_Tg(TNFSF11)5516Edou/0
  http://metadb.riken.jp/0000066IC57BL6JCBAJTgTNFSF115516Edou0TgTNFSF115516Edou
• osteoporosis_Tg(TNFSF11)5519Edou/0
  http://metadb.riken.jp/0000066IC57BL6JCBAJTgTNFSF115519Edou0TgTNFSF115519Edou
• abnormal tooth eruption_Tg(TNFSF11)5516Edou/0,Tnfsf11<tles>/Tnfsf11<tles>
  http://metadb.riken.jp/0000119I129S6SvEvTacC57BL6JCBAJTgTNFSF115516Edou0Tnfsf11tlesTnfsf11tlesTgTNFSF115516EdouTnfsf11tles
• abnormal trabecular bone morphology_Tg(TNFSF11)5516Edou/0
  http://metadb.riken.jp/0000130IC57BL6JCBAJTgTNFSF115516Edou0TgTNFSF115516Edou
• decreased compact bone thickness_Tg(TNFSF11)5519Edou/0
  http://metadb.riken.jp/0000135IC57BL6JCBAJTgTNFSF115519Edou0TgTNFSF115519Edou
• abnormal cartilage morphology_Tg(TNFSF11)5519Edou/0
  http://metadb.riken.jp/0000163IC57BL6JCBAJTgTNFSF115519Edou0TgTNFSF115519Edou
他22件を見る
• no abnormal phenotype detected_Tg(TNFSF11)5519Edou/0,Tnfsf11<tles>/Tnfsf11<tles>
  http://metadb.riken.jp/0002169I129S6SvEvTacC57BL6JCBAJTgTNFSF115519Edou0Tnfsf11tlesTnfsf11tlesTgTNFSF115519EdouTnfsf11tles
• increased circulating alkaline phosphatase level_Tg(TNFSF11)5519Edou/0
  http://metadb.riken.jp/0002968IC57BL6JCBAJTgTNFSF115519Edou0TgTNFSF115519Edou
• abnormal bone remodeling_Tg(TNFSF11)5519Edou/0
  http://metadb.riken.jp/0002998IC57BL6JCBAJTgTNFSF115519Edou0TgTNFSF115519Edou
• short femur_Tg(TNFSF11)5519Edou/0
  http://metadb.riken.jp/0003109IC57BL6JCBAJTgTNFSF115519Edou0TgTNFSF115519Edou
• abnormal compact bone morphology_Tg(TNFSF11)5519Edou/0
  http://metadb.riken.jp/0003797IC57BL6JCBAJTgTNFSF115519Edou0TgTNFSF115519Edou
• increased osteoclast cell number_Tg(TNFSF11)5519Edou/0
  http://metadb.riken.jp/0004984IC57BL6JCBAJTgTNFSF115519Edou0TgTNFSF115519Edou
• decreased bone strength_Tg(TNFSF11)5516Edou/0
  http://metadb.riken.jp/0004991IC57BL6JCBAJTgTNFSF115516Edou0TgTNFSF115516Edou
• decreased bone strength_Tg(TNFSF11)5519Edou/0
  http://metadb.riken.jp/0004991IC57BL6JCBAJTgTNFSF115519Edou0TgTNFSF115519Edou
• increased bone resorption_Tg(TNFSF11)5519Edou/0
  http://metadb.riken.jp/0004992IC57BL6JCBAJTgTNFSF115519Edou0TgTNFSF115519Edou
• abnormal epiphyseal plate morphology_Tg(TNFSF11)5519Edou/0
  http://metadb.riken.jp/0006395IC57BL6JCBAJTgTNFSF115519Edou0TgTNFSF115519Edou
• absent lymph nodes_Tg(TNFSF11)5516Edou/0,Tnfsf11<tles>/Tnfsf11<tles>
  http://metadb.riken.jp/0008024I129S6SvEvTacC57BL6JCBAJTgTNFSF115516Edou0Tnfsf11tlesTnfsf11tlesTgTNFSF115516EdouTnfsf11tles
• increased diameter of femur_Tg(TNFSF11)5519Edou/0
  http://metadb.riken.jp/0008158IC57BL6JCBAJTgTNFSF115519Edou0TgTNFSF115519Edou
• abnormal bone trabecula morphology_Tg(TNFSF11)5519Edou/0
  http://metadb.riken.jp/0010867IC57BL6JCBAJTgTNFSF115519Edou0TgTNFSF115519Edou
• decreased bone trabecula number_Tg(TNFSF11)5516Edou/0
  http://metadb.riken.jp/0010869IC57BL6JCBAJTgTNFSF115516Edou0TgTNFSF115516Edou
• decreased bone trabecula number_Tg(TNFSF11)5519Edou/0
  http://metadb.riken.jp/0010869IC57BL6JCBAJTgTNFSF115519Edou0TgTNFSF115519Edou
• decreased trabecular bone volume_Tg(TNFSF11)5516Edou/0
  http://metadb.riken.jp/0010879IC57BL6JCBAJTgTNFSF115516Edou0TgTNFSF115516Edou
• decreased trabecular bone connectivity density_Tg(TNFSF11)5516Edou/0
  http://metadb.riken.jp/0010933IC57BL6JCBAJTgTNFSF115516Edou0TgTNFSF115516Edou
• decreased compact bone volume_Tg(TNFSF11)5519Edou/0
  http://metadb.riken.jp/0010965IC57BL6JCBAJTgTNFSF115519Edou0TgTNFSF115519Edou
• increased bone trabecular spacing_Tg(TNFSF11)5516Edou/0
  http://metadb.riken.jp/0013630IC57BL6JCBAJTgTNFSF115516Edou0TgTNFSF115516Edou
• decreased femur stiffness_Tg(TNFSF11)5516Edou/0
  http://metadb.riken.jp/0013638IC57BL6JCBAJTgTNFSF115516Edou0TgTNFSF115516Edou
• decreased femur stiffness_Tg(TNFSF11)5519Edou/0
  http://metadb.riken.jp/0013638IC57BL6JCBAJTgTNFSF115519Edou0TgTNFSF115519Edou
• increased bone marrow adipose tissue amount_Tg(TNFSF11)5519Edou/0
  http://metadb.riken.jp/0030009IC57BL6JCBAJTgTNFSF115519Edou0TgTNFSF115519Edou

class

http://purl.org/net/cito/citesAsAuthority

• Tg(TNFSF11)5516Edou
  http://metadb.riken.jp/db/mgi_rdf/MGI:5788418
• Tg(TNFSF11)5519Edou
  http://metadb.riken.jp/db/mgi_rdf/MGI:5788420