Theo. Hatzipetros, et.al., C57BL/6J congenic Prp-TDP43A315T mice develop progressive neurodegeneration in the myenteric plexus of the colon without exhibiting key features of ALS., Brain research, 2014, 1584

http://rdf.ncbi.nlm.nih.gov/pubmed/24141148

Theo. Hatzipetros, et.al., C57BL/6J congenic Prp-TDP43A315T mice develop progressive neurodegeneration in the myenteric plexus of the colon without exhibiting key features of ALS., Brain research, 2014, 1584

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• disheveled coat_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0001511B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• impaired coordination_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0001405B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• extended life span_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0001661FVBNJxB6CgTgPrnpTARDBPA315T95BaloJF1TgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• extended life span_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0001661129S1SvImJxB6CgTgPrnpTARDBPA315T95BaloJF1TgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• abnormal intestine physiology_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0010155C3HHeJxB6CgTgPrnpTARDBPA315T95BaloJF1TgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• limb grasping_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0001513B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• intestinal edema_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0003288B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• dehydration_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0001429B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• hypoactivity_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0001402B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• abnormal intestine physiology_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0010155B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• abnormal intestine physiology_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0010155129S1SvImJxB6CgTgPrnpTARDBPA315T95BaloJF1TgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• abnormal intestine physiology_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0010155PWKPhJxB6CgTgPrnpTARDBPA315T95BaloJF1TgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• premature death_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0002083B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• abnormal induced morbidity/mortality_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0001657B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• weight loss_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0001263B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• abnormal myenteric nerve plexus morphology_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0010801B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• decreased defecation amount_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0012311B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• abnormal enteric ganglia morphology_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0001045B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• extended life span_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0001661ALRLtJxB6CgTgPrnpTARDBPA315T95BaloJF1TgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• abnormal intestine physiology_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0010155WSBEiJxB6CgTgPrnpTARDBPA315T95BaloJF1TgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• impaired righting response_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0001523B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• extended life span_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0001661PWKPhJxB6CgTgPrnpTARDBPA315T95BaloJF1TgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• distended abdomen_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0001270B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• extended life span_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0001661C3HHeJxB6CgTgPrnpTARDBPA315T95BaloJF1TgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• abnormal intestine physiology_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0010155FVBNJxB6CgTgPrnpTARDBPA315T95BaloJF1TgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• motor neuron degeneration_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0000938B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• tail dragging_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0005507B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• astrocytosis_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0003354B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• abnormal intestine physiology_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0010155ALRLtJxB6CgTgPrnpTARDBPA315T95BaloJF1TgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• abnormal axon morphology_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0005404B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• abnormal intestinal transit time_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0006001B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• deficient enteric cholinergic innervation_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0001040B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• extended life span_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0001661WSBEiJxB6CgTgPrnpTARDBPA315T95BaloJF1TgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• neuronal cytoplasmic inclusions_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0011975B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• kyphosis_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0000160B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• abnormal motor neuron morphology_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0000937B6CgTgPrnpTARDBPA315T95BaloJTgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo