Kihoon. Han, et.al., SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties., Nature, 2013, 503

http://rdf.ncbi.nlm.nih.gov/pubmed/24153177

Kihoon. Han, et.al., SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties., Nature, 2013, 503

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Shank3-EGFP)1Hzo
  http://metadb.riken.jp/db/mgi_rdf/MGI:5515936

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Shank3-EGFP)1Hzo
  http://metadb.riken.jp/db/mgi_rdf/MGI:5515936

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased startle reflex_Tg(Shank3-EGFP)1Hzo/0
  http://metadb.riken.jp/0001488IFVBNTgShank3EGFP1Hzo0TgShank3EGFP1Hzo
• abnormal dendritic spine morphology_Tg(Shank3-EGFP)1Hzo/0
  http://metadb.riken.jp/0009936IFVBNTgShank3EGFP1Hzo0TgShank3EGFP1Hzo
• abnormal circadian rhythm_Tg(Shank3-EGFP)1Hzo/0
  http://metadb.riken.jp/0001502IFVBNTgShank3EGFP1Hzo0TgShank3EGFP1Hzo
• abnormal miniature inhibitory postsynaptic currents_Tg(Shank3-EGFP)1Hzo/0
  http://metadb.riken.jp/0009435IFVBNTgShank3EGFP1Hzo0TgShank3EGFP1Hzo
• abnormal social/conspecific interaction_Tg(Shank3-EGFP)1Hzo/0
  http://metadb.riken.jp/0002557IFVBNTgShank3EGFP1Hzo0TgShank3EGFP1Hzo
• decreased prepulse inhibition_Tg(Shank3-EGFP)1Hzo/0
  http://metadb.riken.jp/0009142IFVBNTgShank3EGFP1Hzo0TgShank3EGFP1Hzo
• polyphagia_Tg(Shank3-EGFP)1Hzo/0
  http://metadb.riken.jp/0001433IFVBNTgShank3EGFP1Hzo0TgShank3EGFP1Hzo
• abnormal emotion/affect behavior_Tg(Shank3-EGFP)1Hzo/0
  http://metadb.riken.jp/0002572IFVBNTgShank3EGFP1Hzo0TgShank3EGFP1Hzo
• abnormal hippocampus pyramidal cell morphology_Tg(Shank3-EGFP)1Hzo/0
  http://metadb.riken.jp/0009940IFVBNTgShank3EGFP1Hzo0TgShank3EGFP1Hzo
• increased body weight_Tg(Shank3-EGFP)1Hzo/0
  http://metadb.riken.jp/0001260IFVBNTgShank3EGFP1Hzo0TgShank3EGFP1Hzo
• abnormal synapse morphology_Tg(Shank3-EGFP)1Hzo/0
  http://metadb.riken.jp/0009538IFVBNTgShank3EGFP1Hzo0TgShank3EGFP1Hzo
• decreased vocalization_Tg(Shank3-EGFP)1Hzo/0
  http://metadb.riken.jp/0020351IFVBNTgShank3EGFP1Hzo0TgShank3EGFP1Hzo
• hyperactivity_Tg(Shank3-EGFP)1Hzo/0
  http://metadb.riken.jp/0001399IFVBNTgShank3EGFP1Hzo0TgShank3EGFP1Hzo
• abnormal habituation to a new environment_Tg(Shank3-EGFP)1Hzo/0
  http://metadb.riken.jp/0011620IFVBNTgShank3EGFP1Hzo0TgShank3EGFP1Hzo
• increased excitatory postsynaptic current amplitude_Tg(Shank3-EGFP)1Hzo/0
  http://metadb.riken.jp/0011269IFVBNTgShank3EGFP1Hzo0TgShank3EGFP1Hzo
• seizures_Tg(Shank3-EGFP)1Hzo/0
  http://metadb.riken.jp/0002064IFVBNTgShank3EGFP1Hzo0TgShank3EGFP1Hzo