Lynn. George, et.al., Familial dysautonomia model reveals Ikbkap deletion causes apoptosis of Pax3+ progenitors and peripheral neurons., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110

http://rdf.ncbi.nlm.nih.gov/pubmed/24173031

Lynn. George, et.al., Familial dysautonomia model reveals Ikbkap deletion causes apoptosis of Pax3+ progenitors and peripheral neurons., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ikbkap<tm1c(KOMP)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5558022

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased neuron number_Ikbkap<tm1c(KOMP)Wtsi>/Ikbkap<tm1c(KOMP)Wtsi>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0008947IC57BL6JC57BL6NCBAJIkbkaptm1cKOMPWtsiIkbkaptm1cKOMPWtsiTgWnt1cre11Rth0Ikbkaptm1cKOMPWtsiTgWnt1cre11Rth
• abnormal neuron differentiation_Ikbkap<tm1c(KOMP)Wtsi>/Ikbkap<tm1c(KOMP)Wtsi>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0009937IC57BL6JC57BL6NCBAJIkbkaptm1cKOMPWtsiIkbkaptm1cKOMPWtsiTgWnt1cre11Rth0Ikbkaptm1cKOMPWtsiTgWnt1cre11Rth
• neonatal lethality, complete penetrance_Ikbkap<tm1c(KOMP)Wtsi>/Ikbkap<tm1c(KOMP)Wtsi>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0011087IC57BL6JC57BL6NCBAJIkbkaptm1cKOMPWtsiIkbkaptm1cKOMPWtsiTgWnt1cre11Rth0Ikbkaptm1cKOMPWtsiTgWnt1cre11Rth
• increased neuron apoptosis_Ikbkap<tm1c(KOMP)Wtsi>/Ikbkap<tm1c(KOMP)Wtsi>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0003203IC57BL6JC57BL6NCBAJIkbkaptm1cKOMPWtsiIkbkaptm1cKOMPWtsiTgWnt1cre11Rth0Ikbkaptm1cKOMPWtsiTgWnt1cre11Rth
• decreased sensory neuron number_Ikbkap<tm1c(KOMP)Wtsi>/Ikbkap<tm1c(KOMP)Wtsi>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0000966IC57BL6JC57BL6NCBAJIkbkaptm1cKOMPWtsiIkbkaptm1cKOMPWtsiTgWnt1cre11Rth0Ikbkaptm1cKOMPWtsiTgWnt1cre11Rth
• retrognathia_Ikbkap<tm1c(KOMP)Wtsi>/Ikbkap<tm1c(KOMP)Wtsi>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0004282IC57BL6JC57BL6NCBAJIkbkaptm1cKOMPWtsiIkbkaptm1cKOMPWtsiTgWnt1cre11Rth0Ikbkaptm1cKOMPWtsiTgWnt1cre11Rth
• abnormal submandibular gland morphology_Ikbkap<tm1c(KOMP)Wtsi>/Ikbkap<tm1c(KOMP)Wtsi>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0003793IC57BL6JC57BL6NCBAJIkbkaptm1cKOMPWtsiIkbkaptm1cKOMPWtsiTgWnt1cre11Rth0Ikbkaptm1cKOMPWtsiTgWnt1cre11Rth
• abnormal sensory neuron innervation pattern_Ikbkap<tm1c(KOMP)Wtsi>/Ikbkap<tm1c(KOMP)Wtsi>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0000968IC57BL6JC57BL6NCBAJIkbkaptm1cKOMPWtsiIkbkaptm1cKOMPWtsiTgWnt1cre11Rth0Ikbkaptm1cKOMPWtsiTgWnt1cre11Rth
• abnormal nervous system physiology_Ikbkap<tm1c(KOMP)Wtsi>/Ikbkap<tm1c(KOMP)Wtsi>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0003633IC57BL6JC57BL6NCBAJIkbkaptm1cKOMPWtsiIkbkaptm1cKOMPWtsiTgWnt1cre11Rth0Ikbkaptm1cKOMPWtsiTgWnt1cre11Rth
• decreased neuron number_Ikbkap<tm1c(KOMP)Wtsi>/Ikbkap<tm1c(KOMP)Wtsi>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0008948IC57BL6JC57BL6NCBAJIkbkaptm1cKOMPWtsiIkbkaptm1cKOMPWtsiTgWnt1cre11Rth0Ikbkaptm1cKOMPWtsiTgWnt1cre11Rth
• abnormal facial morphology_Ikbkap<tm1c(KOMP)Wtsi>/Ikbkap<tm1c(KOMP)Wtsi>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0003743IC57BL6JC57BL6NCBAJIkbkaptm1cKOMPWtsiIkbkaptm1cKOMPWtsiTgWnt1cre11Rth0Ikbkaptm1cKOMPWtsiTgWnt1cre11Rth
• abnormal dorsal root ganglion morphology_Ikbkap<tm1c(KOMP)Wtsi>/Ikbkap<tm1c(KOMP)Wtsi>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0000961IC57BL6JC57BL6NCBAJIkbkaptm1cKOMPWtsiIkbkaptm1cKOMPWtsiTgWnt1cre11Rth0Ikbkaptm1cKOMPWtsiTgWnt1cre11Rth
• decreased fetal size_Ikbkap<tm1c(KOMP)Wtsi>/Ikbkap<tm1c(KOMP)Wtsi>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0004200IC57BL6JC57BL6NCBAJIkbkaptm1cKOMPWtsiIkbkaptm1cKOMPWtsiTgWnt1cre11Rth0Ikbkaptm1cKOMPWtsiTgWnt1cre11Rth
• abnormal superior cervical ganglion morphology_Ikbkap<tm1c(KOMP)Wtsi>/Ikbkap<tm1c(KOMP)Wtsi>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0001011IC57BL6JC57BL6NCBAJIkbkaptm1cKOMPWtsiIkbkaptm1cKOMPWtsiTgWnt1cre11Rth0Ikbkaptm1cKOMPWtsiTgWnt1cre11Rth

class

http://purl.org/net/cito/citesAsAuthority

• Ikbkap<tm1c(KOMP)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5558022