Briana E. Rockich, et.al., Sox9 plays multiple roles in the lung epithelium during branching morphogenesis., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110

http://rdf.ncbi.nlm.nih.gov/pubmed/24191021

Briana E. Rockich, et.al., Sox9 plays multiple roles in the lung epithelium during branching morphogenesis., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(tetO-Sox9)Msan>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5557984

class

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(tetO-Sox9)Msan>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5557984

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal branching involved in lung morphogenesis_Sox9<tm1Gsr>/Sox9<tm1Gsr>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0011024I129P2OlaHsdSox9tm1GsrSox9tm1GsrShhtm1EGFPcreCjtShhSox9tm1GsrShhShhtm1EGFPcreCjt
• abnormal lung morphology_Gt(ROSA)26Sor<tm1(tetO-Sox9)Msan>/Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0001175I129S1Sv129X1SvJGtROSA26Sortm1tetOSox9MsanGtROSA26Sortm1rtTAEGFPNagyShhtm1EGFPcreCjtShhGtROSA26Sortm1tetOSox9MsanGtROSA26Sortm1rtTAEGFPNagyShhShhtm1EGFPcreCjt
• perinatal lethality, incomplete penetrance_Sox9<tm1Gsr>/Sox9<tm1Gsr>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0011090I129P2OlaHsdSox9tm1GsrSox9tm1GsrShhtm1EGFPcreCjtShhSox9tm1GsrShhShhtm1EGFPcreCjt
• abnormal cell differentiation_Gt(ROSA)26Sor<tm1(tetO-Sox9)Msan>/Gt(ROSA)26Sor<+>,Tg(SFTPC-rtTA)5Jaw/0
  http://metadb.riken.jp/0005076NSGtROSA26Sortm1tetOSox9MsanGtROSA26SorTgSFTPCrtTA5Jaw0TgSFTPCrtTA5JawGtROSA26SorGtROSA26Sortm1tetOSox9Msan
• abnormal pulmonary alveolus epithelium morphology_Gt(ROSA)26Sor<tm1(tetO-Sox9)Msan>/Gt(ROSA)26Sor<+>,Tg(SFTPC-rtTA)5Jaw/0
  http://metadb.riken.jp/0010898NSGtROSA26Sortm1tetOSox9MsanGtROSA26SorTgSFTPCrtTA5Jaw0TgSFTPCrtTA5JawGtROSA26SorGtROSA26Sortm1tetOSox9Msan
• decreased cell proliferation_Sox9<tm1Gsr>/Sox9<tm1Gsr>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0000352I129P2OlaHsdSox9tm1GsrSox9tm1GsrShhtm1EGFPcreCjtShhSox9tm1GsrShhShhtm1EGFPcreCjt
• abnormal lung epithelium morphology_Sox9<tm1Gsr>/Sox9<tm1Gsr>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0006382I129P2OlaHsdSox9tm1GsrSox9tm1GsrShhtm1EGFPcreCjtShhSox9tm1GsrShhShhtm1EGFPcreCjt
• perinatal lethality, complete penetrance_Gt(ROSA)26Sor<tm1(tetO-Sox9)Msan>/Gt(ROSA)26Sor<+>,Tg(SFTPC-rtTA)5Jaw/0
  http://metadb.riken.jp/0011089NSGtROSA26Sortm1tetOSox9MsanGtROSA26SorTgSFTPCrtTA5Jaw0TgSFTPCrtTA5JawGtROSA26SorGtROSA26Sortm1tetOSox9Msan
• lung cysts_Gt(ROSA)26Sor<tm1(tetO-Sox9)Msan>/Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0004880I129S1Sv129X1SvJGtROSA26Sortm1tetOSox9MsanGtROSA26Sortm1rtTAEGFPNagyShhtm1EGFPcreCjtShhGtROSA26Sortm1tetOSox9MsanGtROSA26Sortm1rtTAEGFPNagyShhShhtm1EGFPcreCjt
• abnormal cell differentiation_Sox9<tm1Gsr>/Sox9<tm1Gsr>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0005076I129P2OlaHsdSox9tm1GsrSox9tm1GsrShhtm1EGFPcreCjtShhSox9tm1GsrShhShhtm1EGFPcreCjt
• postnatal lethality, complete penetrance_Sox9<tm1Gsr>/Sox9<tm1Gsr>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0011085I129P2OlaHsdSox9tm1GsrSox9tm1GsrShhtm1EGFPcreCjtShhSox9tm1GsrShhShhtm1EGFPcreCjt
• small lung_Gt(ROSA)26Sor<tm1(tetO-Sox9)Msan>/Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0003641I129S1Sv129X1SvJGtROSA26Sortm1tetOSox9MsanGtROSA26Sortm1rtTAEGFPNagyShhtm1EGFPcreCjtShhGtROSA26Sortm1tetOSox9MsanGtROSA26Sortm1rtTAEGFPNagyShhShhtm1EGFPcreCjt
• small lung_Sox9<tm1Gsr>/Sox9<tm1Gsr>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0003641I129P2OlaHsdSox9tm1GsrSox9tm1GsrShhtm1EGFPcreCjtShhSox9tm1GsrShhShhtm1EGFPcreCjt
• decreased cell migration_Sox9<tm1Gsr>/Sox9<tm1Gsr>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0011805I129P2OlaHsdSox9tm1GsrSox9tm1GsrShhtm1EGFPcreCjtShhSox9tm1GsrShhShhtm1EGFPcreCjt
• respiratory distress_Sox9<tm1Gsr>/Sox9<tm1Gsr>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0001954I129P2OlaHsdSox9tm1GsrSox9tm1GsrShhtm1EGFPcreCjtShhSox9tm1GsrShhShhtm1EGFPcreCjt
• lung cysts_Sox9<tm1Gsr>/Sox9<tm1Gsr>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0004880I129P2OlaHsdSox9tm1GsrSox9tm1GsrShhtm1EGFPcreCjtShhSox9tm1GsrShhShhtm1EGFPcreCjt