Omar. Abdel-Wahab, et.al., Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo., The Journal of experimental medicine, 2013, 210

http://rdf.ncbi.nlm.nih.gov/pubmed/24218140

Omar. Abdel-Wahab, et.al., Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo., The Journal of experimental medicine, 2013, 210

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Asxl1<tm1.1Iaai>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5575656
• Asxl1<tm1.2Iaai>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5575657

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased mature B cell number_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008211I129SSvEvC57BL6CBAAsxl1tm11IaaiAsxl1tm11IaaiTgMx1cre1Cgn0TgMx1cre1CgnAsxl1tm11Iaai
• abnormal hematopoietic stem cell morphology_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0004808I129SSvEvC57BL6Asxl1tm11IaaiAsxl1tm11IaaiTgVav1cre1Graf0TgVav1cre1GrafAsxl1tm11Iaai
• abnormal skeleton morphology_Asxl1<tm1.2Iaai>/Asxl1<tm1.2Iaai>
  http://metadb.riken.jp/0005508I129SSvEvC57BL6Asxl1tm12IaaiAsxl1tm12IaaiAsxl1tm12Iaai
• increased erythroid progenitor cell number_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0003135I129SSvEvC57BL6Asxl1tm11IaaiAsxl1tm11IaaiTgVav1cre1Graf0TgVav1cre1GrafAsxl1tm11Iaai
• abnormal myelopoiesis_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tet2<tm1.1Iaai>/Tet2<tm1.1Iaai>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001601I129SSvEvC57BL6CBAAsxl1tm11IaaiAsxl1tm11IaaiTet2tm11IaaiTet2tm11IaaiTgMx1cre1Cgn0TgMx1cre1CgnTet2tm11IaaiAsxl1tm11Iaai
• decreased neutrophil cell number_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0000222I129SSvEvC57BL6Asxl1tm11IaaiAsxl1tm11IaaiTgVav1cre1Graf0TgVav1cre1GrafAsxl1tm11Iaai
• abnormal myelopoiesis_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0001601I129SSvEvC57BL6Asxl1tm11IaaiAsxl1tm11IaaiTgVav1cre1Graf0TgVav1cre1GrafAsxl1tm11Iaai
• increased nucleated erythrocyte cell number_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0009395I129SSvEvC57BL6Asxl1tm11IaaiAsxl1tm11IaaiTgVav1cre1Graf0TgVav1cre1GrafAsxl1tm11Iaai
• abnormal craniofacial morphology_Asxl1<tm1.2Iaai>/Asxl1<+>
  http://metadb.riken.jp/0000428I129SSvEvC57BL6Asxl1tm12IaaiAsxl1Asxl1Asxl1tm12Iaai
• abnormal myelopoiesis_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001601I129SSvEvC57BL6CBAAsxl1tm11IaaiAsxl1tm11IaaiTgMx1cre1Cgn0TgMx1cre1CgnAsxl1tm11Iaai
• extramedullary hematopoiesis_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000240I129SSvEvC57BL6CBAAsxl1tm11IaaiAsxl1tm11IaaiTgMx1cre1Cgn0TgMx1cre1CgnAsxl1tm11Iaai
• decreased hemoglobin content_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002874I129SSvEvC57BL6CBAAsxl1tm11IaaiAsxl1tm11IaaiTgMx1cre1Cgn0TgMx1cre1CgnAsxl1tm11Iaai
• premature death_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tet2<tm1.1Iaai>/Tet2<tm1.1Iaai>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002083I129SSvEvC57BL6CBAAsxl1tm11IaaiAsxl1tm11IaaiTet2tm11IaaiTet2tm11IaaiTgMx1cre1Cgn0TgMx1cre1CgnTet2tm11IaaiAsxl1tm11Iaai
• premature death_Tet2<tm1.1Iaai>/Tet2<tm1.1Iaai>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002083I129SSvEvC57BL6CBATet2tm11IaaiTet2tm11IaaiTgMx1cre1Cgn0TgMx1cre1CgnTet2tm11Iaai
• anemia_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0001577I129SSvEvC57BL6Asxl1tm11IaaiAsxl1tm11IaaiTgVav1cre1Graf0TgVav1cre1GrafAsxl1tm11Iaai
• increased hematopoietic stem cell number_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0004809I129SSvEvC57BL6Asxl1tm11IaaiAsxl1tm11IaaiTgVav1cre1Graf0TgVav1cre1GrafAsxl1tm11Iaai
• microphthalmia_Asxl1<tm1.2Iaai>/Asxl1<tm1.2Iaai>
  http://metadb.riken.jp/0001297I129SSvEvC57BL6Asxl1tm12IaaiAsxl1tm12IaaiAsxl1tm12Iaai
• decreased splenocyte number_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0009339I129SSvEvC57BL6Asxl1tm11IaaiAsxl1tm11IaaiTgVav1cre1Graf0TgVav1cre1GrafAsxl1tm11Iaai
• abnormal hyoid bone morphology_Asxl1<tm1.2Iaai>/Asxl1<tm1.2Iaai>
  http://metadb.riken.jp/0003056I129SSvEvC57BL6Asxl1tm12IaaiAsxl1tm12IaaiAsxl1tm12Iaai
• anophthalmia_Asxl1<tm1.2Iaai>/Asxl1<tm1.2Iaai>
  http://metadb.riken.jp/0001293I129SSvEvC57BL6Asxl1tm12IaaiAsxl1tm12IaaiAsxl1tm12Iaai
• decreased neutrophil cell number_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000222I129SSvEvC57BL6CBAAsxl1tm11IaaiAsxl1tm11IaaiTgMx1cre1Cgn0TgMx1cre1CgnAsxl1tm11Iaai
• lethality throughout fetal growth and development, complete penetrance_Asxl1<tm1.2Iaai>/Asxl1<tm1.2Iaai>
  http://metadb.riken.jp/0011099I129SSvEvC57BL6Asxl1tm12IaaiAsxl1tm12IaaiAsxl1tm12Iaai
• increased nucleated erythrocyte cell number_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0009395I129SSvEvC57BL6CBAAsxl1tm11IaaiAsxl1tm11IaaiTgMx1cre1Cgn0TgMx1cre1CgnAsxl1tm11Iaai
• cleft palate_Asxl1<tm1.2Iaai>/Asxl1<tm1.2Iaai>
  http://metadb.riken.jp/0000111I129SSvEvC57BL6Asxl1tm12IaaiAsxl1tm12IaaiAsxl1tm12Iaai
• vertebral transformation_Asxl1<tm1.2Iaai>/Asxl1<tm1.2Iaai>
  http://metadb.riken.jp/0003036I129SSvEvC57BL6Asxl1tm12IaaiAsxl1tm12IaaiAsxl1tm12Iaai
• decreased leukocyte cell number_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0000221I129SSvEvC57BL6Asxl1tm11IaaiAsxl1tm11IaaiTgVav1cre1Graf0TgVav1cre1GrafAsxl1tm11Iaai
• decreased mature B cell number_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0008211I129SSvEvC57BL6Asxl1tm11IaaiAsxl1tm11IaaiTgVav1cre1Graf0TgVav1cre1GrafAsxl1tm11Iaai
• decreased bone marrow cell number_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0000333I129SSvEvC57BL6Asxl1tm11IaaiAsxl1tm11IaaiTgVav1cre1Graf0TgVav1cre1GrafAsxl1tm11Iaai
• abnormal definitive hematopoiesis_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0002123I129SSvEvC57BL6Asxl1tm11IaaiAsxl1tm11IaaiTgVav1cre1Graf0TgVav1cre1GrafAsxl1tm11Iaai
• increased erythroid progenitor cell number_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0003135I129SSvEvC57BL6CBAAsxl1tm11IaaiAsxl1tm11IaaiTgMx1cre1Cgn0TgMx1cre1CgnAsxl1tm11Iaai
• decreased hemoglobin content_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0002874I129SSvEvC57BL6Asxl1tm11IaaiAsxl1tm11IaaiTgVav1cre1Graf0TgVav1cre1GrafAsxl1tm11Iaai
• decreased leukocyte cell number_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000221I129SSvEvC57BL6CBAAsxl1tm11IaaiAsxl1tm11IaaiTgMx1cre1Cgn0TgMx1cre1CgnAsxl1tm11Iaai
• decreased monocyte cell number_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0000223I129SSvEvC57BL6Asxl1tm11IaaiAsxl1tm11IaaiTgVav1cre1Graf0TgVav1cre1GrafAsxl1tm11Iaai
• decreased monocyte cell number_Asxl1<tm1.1Iaai>/Asxl1<tm1.1Iaai>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000223I129SSvEvC57BL6CBAAsxl1tm11IaaiAsxl1tm11IaaiTgMx1cre1Cgn0TgMx1cre1CgnAsxl1tm11Iaai
• mandible hypoplasia_Asxl1<tm1.2Iaai>/Asxl1<tm1.2Iaai>
  http://metadb.riken.jp/0000460I129SSvEvC57BL6Asxl1tm12IaaiAsxl1tm12IaaiAsxl1tm12Iaai

class

http://purl.org/net/cito/citesAsAuthority

• Asxl1<tm1.1Iaai>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5575656
• Asxl1<tm1.2Iaai>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5575657