Charlotte. Whitmore, et.al., The transgenic expression of LARGE exacerbates the muscle phenotype of dystroglycanopathy mice., Human molecular genetics, 2014, 23

http://rdf.ncbi.nlm.nih.gov/pubmed/24234655

Charlotte. Whitmore, et.al., The transgenic expression of LARGE exacerbates the muscle phenotype of dystroglycanopathy mice., Human molecular genetics, 2014, 23

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• dystrophic muscle_Fkrp<tm1Scbr>/Fkrp<tm1Scbr>,Sox1<tm1(cre)Take>/Sox1<+>,Tg(CAG-LARGE)126Fmu/0
  http://metadb.riken.jp/0000752IC57BL6NCrljC57BL10CBACaCBAJNCrljFkrptm1ScbrFkrptm1ScbrSox1tm1creTakeSox1TgCAGLARGE126Fmu0Sox1Fkrptm1ScbrSox1tm1creTakeTgCAGLARGE126Fmu
• skeletal muscle hypertrophy_Fkrp<tm1Scbr>/Fkrp<tm1Scbr>,Sox1<tm1(cre)Take>/Sox1<+>,Tg(CAG-LARGE)126Fmu/0
  http://metadb.riken.jp/0009461IC57BL6NCrljC57BL10CBACaCBAJNCrljFkrptm1ScbrFkrptm1ScbrSox1tm1creTakeSox1TgCAGLARGE126Fmu0Sox1Fkrptm1ScbrSox1tm1creTakeTgCAGLARGE126Fmu
• hydroencephaly_Fkrp<tm1Scbr>/Fkrp<tm1Scbr>,Sox1<tm1(cre)Take>/Sox1<+>
  http://metadb.riken.jp/0001891IC57BL6NCrljCBAJNCrljFkrptm1ScbrFkrptm1ScbrSox1tm1creTakeSox1Fkrptm1ScbrSox1tm1creTakeSox1
• centrally nucleated skeletal muscle fibers_Fkrp<tm1Scbr>/Fkrp<tm1Scbr>,Sox1<tm1(cre)Take>/Sox1<+>,Tg(CAG-LARGE)126Fmu/0
  http://metadb.riken.jp/0009404IC57BL6NCrljC57BL10CBACaCBAJNCrljFkrptm1ScbrFkrptm1ScbrSox1tm1creTakeSox1TgCAGLARGE126Fmu0Sox1Fkrptm1ScbrSox1tm1creTakeTgCAGLARGE126Fmu
• myositis_Fkrp<tm1Scbr>/Fkrp<tm1Scbr>,Sox1<tm1(cre)Take>/Sox1<+>,Tg(CAG-LARGE)126Fmu/0
  http://metadb.riken.jp/0004510IC57BL6NCrljC57BL10CBACaCBAJNCrljFkrptm1ScbrFkrptm1ScbrSox1tm1creTakeSox1TgCAGLARGE126Fmu0Sox1Fkrptm1ScbrSox1tm1creTakeTgCAGLARGE126Fmu
• muscle degeneration_Fkrp<tm1Scbr>/Fkrp<tm1Scbr>,Sox1<tm1(cre)Take>/Sox1<+>
  http://metadb.riken.jp/0000749IC57BL6NCrljCBAJNCrljFkrptm1ScbrFkrptm1ScbrSox1tm1creTakeSox1Fkrptm1ScbrSox1tm1creTakeSox1
• abnormal muscle physiology_Fkrp<tm1Scbr>/Fkrp<tm1Scbr>,Sox1<tm1(cre)Take>/Sox1<+>,Tg(CAG-LARGE)126Fmu/0
  http://metadb.riken.jp/0002106IC57BL6NCrljC57BL10CBACaCBAJNCrljFkrptm1ScbrFkrptm1ScbrSox1tm1creTakeSox1TgCAGLARGE126Fmu0Sox1Fkrptm1ScbrSox1tm1creTakeTgCAGLARGE126Fmu
• premature death_Fkrp<tm1Scbr>/Fkrp<tm1Scbr>,Sox1<tm1(cre)Take>/Sox1<+>,Tg(CAG-LARGE)126Fmu/0
  http://metadb.riken.jp/0002083IC57BL6NCrljC57BL10CBACaCBAJNCrljFkrptm1ScbrFkrptm1ScbrSox1tm1creTakeSox1TgCAGLARGE126Fmu0Sox1Fkrptm1ScbrSox1tm1creTakeTgCAGLARGE126Fmu
• abnormal muscle morphology_Fkrp<tm1Scbr>/Fkrp<tm1Scbr>,Sox1<tm1(cre)Take>/Sox1<+>,Tg(CAG-LARGE)126Fmu/0
  http://metadb.riken.jp/0002108IC57BL6NCrljC57BL10CBACaCBAJNCrljFkrptm1ScbrFkrptm1ScbrSox1tm1creTakeSox1TgCAGLARGE126Fmu0Sox1Fkrptm1ScbrSox1tm1creTakeTgCAGLARGE126Fmu
• calcified muscle_Fkrp<tm1Scbr>/Fkrp<tm1Scbr>,Sox1<tm1(cre)Take>/Sox1<+>,Tg(CAG-LARGE)126Fmu/0
  http://metadb.riken.jp/0003199IC57BL6NCrljC57BL10CBACaCBAJNCrljFkrptm1ScbrFkrptm1ScbrSox1tm1creTakeSox1TgCAGLARGE126Fmu0Sox1Fkrptm1ScbrSox1tm1creTakeTgCAGLARGE126Fmu
• skeletal muscle fibrosis_Fkrp<tm1Scbr>/Fkrp<tm1Scbr>,Sox1<tm1(cre)Take>/Sox1<+>,Tg(CAG-LARGE)126Fmu/0
  http://metadb.riken.jp/0009419IC57BL6NCrljC57BL10CBACaCBAJNCrljFkrptm1ScbrFkrptm1ScbrSox1tm1creTakeSox1TgCAGLARGE126Fmu0Sox1Fkrptm1ScbrSox1tm1creTakeTgCAGLARGE126Fmu
• abnormal reflex_Fkrp<tm1Scbr>/Fkrp<tm1Scbr>,Sox1<tm1(cre)Take>/Sox1<+>,Tg(CAG-LARGE)126Fmu/0
  http://metadb.riken.jp/0001961IC57BL6NCrljC57BL10CBACaCBAJNCrljFkrptm1ScbrFkrptm1ScbrSox1tm1creTakeSox1TgCAGLARGE126Fmu0Sox1Fkrptm1ScbrSox1tm1creTakeTgCAGLARGE126Fmu
• decreased body weight_Fkrp<tm1Scbr>/Fkrp<tm1Scbr>,Sox1<tm1(cre)Take>/Sox1<+>
  http://metadb.riken.jp/0001262IC57BL6NCrljCBAJNCrljFkrptm1ScbrFkrptm1ScbrSox1tm1creTakeSox1Fkrptm1ScbrSox1tm1creTakeSox1
• myositis_Fkrp<tm1Scbr>/Fkrp<tm1Scbr>,Sox1<tm1(cre)Take>/Sox1<+>
  http://metadb.riken.jp/0004510IC57BL6NCrljCBAJNCrljFkrptm1ScbrFkrptm1ScbrSox1tm1creTakeSox1Fkrptm1ScbrSox1tm1creTakeSox1
• dystrophic muscle_Fkrp<tm1Scbr>/Fkrp<tm1Scbr>,Sox1<tm1(cre)Take>/Sox1<+>
  http://metadb.riken.jp/0000752IC57BL6NCrljCBAJNCrljFkrptm1ScbrFkrptm1ScbrSox1tm1creTakeSox1Fkrptm1ScbrSox1tm1creTakeSox1
• postnatal lethality, incomplete penetrance_Fkrp<tm1Scbr>/Fkrp<tm1Scbr>,Sox1<tm1(cre)Take>/Sox1<+>
  http://metadb.riken.jp/0011086IC57BL6NCrljCBAJNCrljFkrptm1ScbrFkrptm1ScbrSox1tm1creTakeSox1Fkrptm1ScbrSox1tm1creTakeSox1
• centrally nucleated skeletal muscle fibers_Fkrp<tm1Scbr>/Fkrp<tm1Scbr>,Sox1<tm1(cre)Take>/Sox1<+>
  http://metadb.riken.jp/0009404IC57BL6NCrljCBAJNCrljFkrptm1ScbrFkrptm1ScbrSox1tm1creTakeSox1Fkrptm1ScbrSox1tm1creTakeSox1