Sarah. Sczelecki, et.al., Loss of Pgc-1α expression in aging mouse muscle potentiates glucose intolerance and systemic inflammation., American journal of physiology. Endocrinology and metabolism, 2014, 306

http://rdf.ncbi.nlm.nih.gov/pubmed/24280126

Sarah. Sczelecki, et.al., Loss of Pgc-1α expression in aging mouse muscle potentiates glucose intolerance and systemic inflammation., American journal of physiology. Endocrinology and metabolism, 2014, 306

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ppargc1a<tm2.1Brsp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5576884

class

http://purl.org/net/cito/citesAsAuthority

• Ppargc1a<tm2.1Brsp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5576884

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• impaired glucose tolerance_Ppargc1a<tm2.1Brsp>/Ppargc1a<tm2.1Brsp>,Tg(Myog-cre)1Eno/0
  http://metadb.riken.jp/0005293I129BALBcC57BL6JC57BL6NPpargc1atm21BrspPpargc1atm21BrspTgMyogcre1Eno0TgMyogcre1EnoPpargc1atm21Brsp
• decreased circulating insulin level_Ppargc1a<tm2.1Brsp>/Ppargc1a<tm2.1Brsp>,Tg(Myog-cre)1Eno/0
  http://metadb.riken.jp/0002727I129BALBcC57BL6JC57BL6NPpargc1atm21BrspPpargc1atm21BrspTgMyogcre1Eno0TgMyogcre1EnoPpargc1atm21Brsp
• decreased respiratory quotient_Ppargc1a<tm2.1Brsp>/Ppargc1a<tm2.1Brsp>,Tg(Myog-cre)1Eno/0
  http://metadb.riken.jp/0010379I129BALBcC57BL6JC57BL6NPpargc1atm21BrspPpargc1atm21BrspTgMyogcre1Eno0TgMyogcre1EnoPpargc1atm21Brsp
• abnormal mitochondrial physiology_Ppargc1a<tm2.1Brsp>/Ppargc1a<tm2.1Brsp>,Tg(Myog-cre)1Eno/0
  http://metadb.riken.jp/0006036I129BALBcC57BL6JC57BL6NPpargc1atm21BrspPpargc1atm21BrspTgMyogcre1Eno0TgMyogcre1EnoPpargc1atm21Brsp
• decreased circulating glucose level_Ppargc1a<tm2.1Brsp>/Ppargc1a<tm2.1Brsp>,Tg(Myog-cre)1Eno/0
  http://metadb.riken.jp/0005560I129BALBcC57BL6JC57BL6NPpargc1atm21BrspPpargc1atm21BrspTgMyogcre1Eno0TgMyogcre1EnoPpargc1atm21Brsp
• increased percent body fat/body weight_Ppargc1a<tm2.1Brsp>/Ppargc1a<tm2.1Brsp>,Tg(Myog-cre)1Eno/0
  http://metadb.riken.jp/0005458I129BALBcC57BL6JC57BL6NPpargc1atm21BrspPpargc1atm21BrspTgMyogcre1Eno0TgMyogcre1EnoPpargc1atm21Brsp
• decreased lean body mass_Ppargc1a<tm2.1Brsp>/Ppargc1a<tm2.1Brsp>,Tg(Myog-cre)1Eno/0
  http://metadb.riken.jp/0003961I129BALBcC57BL6JC57BL6NPpargc1atm21BrspPpargc1atm21BrspTgMyogcre1Eno0TgMyogcre1EnoPpargc1atm21Brsp
• insulin resistance_Ppargc1a<tm2.1Brsp>/Ppargc1a<tm2.1Brsp>,Tg(Myog-cre)1Eno/0
  http://metadb.riken.jp/0005331I129BALBcC57BL6JC57BL6NPpargc1atm21BrspPpargc1atm21BrspTgMyogcre1Eno0TgMyogcre1EnoPpargc1atm21Brsp