Shenglan. Gao, et.al., NCOA5 haploinsufficiency results in glucose intolerance and subsequent hepatocellular carcinoma., Cancer cell, 2013, 24

http://rdf.ncbi.nlm.nih.gov/pubmed/24332041

Shenglan. Gao, et.al., NCOA5 haploinsufficiency results in glucose intolerance and subsequent hepatocellular carcinoma., Cancer cell, 2013, 24

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ncoa5<tm1Hxia>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5581698

class

http://purl.org/net/cito/citesAsAuthority

• Ncoa5<tm1Hxia>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5581698

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• impaired glucose tolerance_Ncoa5<tm1Hxia>/Ncoa5<+>
  http://metadb.riken.jp/0005293I129C57BL6Ncoa5tm1HxiaNcoa5Ncoa5Ncoa5tm1Hxia
• liver fibrosis_Ncoa5<tm1Hxia>/Ncoa5<+>
  http://metadb.riken.jp/0003333I129C57BL6Ncoa5tm1HxiaNcoa5Ncoa5Ncoa5tm1Hxia
• increased fasted circulating glucose level_Ncoa5<tm1Hxia>/Ncoa5<+>
  http://metadb.riken.jp/0013279C129B6Ncoa5tm1HxiaNcoa5tm1HxiaNcoa5Ncoa5tm1HxiaNcoa5
• liver inflammation_Ncoa5<tm1Hxia>/Ncoa5<+>
  http://metadb.riken.jp/0001860I129C57BL6Ncoa5tm1HxiaNcoa5Ncoa5Ncoa5tm1Hxia
• abnormal circulating protein level_Ncoa5<tm1Hxia>/Ncoa5<+>
  http://metadb.riken.jp/0005416I129C57BL6Ncoa5tm1HxiaNcoa5Ncoa5Ncoa5tm1Hxia
• increased hepatocyte proliferation_Ncoa5<tm1Hxia>/Ncoa5<+>
  http://metadb.riken.jp/0003893I129C57BL6Ncoa5tm1HxiaNcoa5Ncoa5Ncoa5tm1Hxia
• small pancreatic islets_Ncoa5<tm1Hxia>/Ncoa5<+>
  http://metadb.riken.jp/0009172I129C57BL6Ncoa5tm1HxiaNcoa5Ncoa5Ncoa5tm1Hxia
• increased hepatocellular carcinoma incidence_Ncoa5<tm1Hxia>/Ncoa5<+>
  http://metadb.riken.jp/0003331C129B6Ncoa5tm1HxiaNcoa5tm1HxiaNcoa5Ncoa5tm1HxiaNcoa5
• abnormal liver morphology_Ncoa5<tm1Hxia>/Ncoa5<+>
  http://metadb.riken.jp/0000598I129C57BL6Ncoa5tm1HxiaNcoa5Ncoa5Ncoa5tm1Hxia
• impaired glucose tolerance_Ncoa5<tm1Hxia>/Ncoa5<+>
  http://metadb.riken.jp/0005293C129B6Ncoa5tm1HxiaNcoa5tm1HxiaNcoa5Ncoa5tm1HxiaNcoa5
• increased circulating alanine transaminase level_Ncoa5<tm1Hxia>/Ncoa5<+>
  http://metadb.riken.jp/0002941I129C57BL6Ncoa5tm1HxiaNcoa5Ncoa5Ncoa5tm1Hxia
• increased liver triglyceride level_Ncoa5<tm1Hxia>/Ncoa5<+>
  http://metadb.riken.jp/0009355I129C57BL6Ncoa5tm1HxiaNcoa5Ncoa5Ncoa5tm1Hxia
• increased hepatocellular carcinoma incidence_Il6<tm1Kopf>/Il6<+>,Ncoa5<tm1Hxia>/Ncoa5<+>
  http://metadb.riken.jp/0003331I129S2SvPasC57BL6Il6tm1KopfIl6Ncoa5tm1HxiaNcoa5Ncoa5tm1HxiaIl6Il6tm1KopfNcoa5
• hepatic steatosis_Ncoa5<tm1Hxia>/Ncoa5<+>
  http://metadb.riken.jp/0002628I129C57BL6Ncoa5tm1HxiaNcoa5Ncoa5Ncoa5tm1Hxia
• increased hepatocyte apoptosis_Ncoa5<tm1Hxia>/Ncoa5<+>
  http://metadb.riken.jp/0003887I129C57BL6Ncoa5tm1HxiaNcoa5Ncoa5Ncoa5tm1Hxia
• increased fasted circulating glucose level_Ncoa5<tm1Hxia>/Ncoa5<+>
  http://metadb.riken.jp/0013279I129C57BL6Ncoa5tm1HxiaNcoa5Ncoa5Ncoa5tm1Hxia
• increased hepatocellular carcinoma incidence_Ncoa5<tm1Hxia>/Ncoa5<+>
  http://metadb.riken.jp/0003331I129C57BL6Ncoa5tm1HxiaNcoa5Ncoa5Ncoa5tm1Hxia
• decreased pancreatic islet number_Ncoa5<tm1Hxia>/Ncoa5<+>
  http://metadb.riken.jp/0009168I129C57BL6Ncoa5tm1HxiaNcoa5Ncoa5Ncoa5tm1Hxia
• preweaning lethality, complete penetrance_Il6<tm1Kopf>/Il6<+>,Ncoa5<tm1Hxia>/Ncoa5<tm1Hxia>
  http://metadb.riken.jp/0011100I129S2SvPasC57BL6Il6tm1KopfIl6Ncoa5tm1HxiaNcoa5tm1HxiaNcoa5tm1HxiaIl6tm1KopfIl6
• male infertility_Ncoa5<tm1Hxia>/Ncoa5<+>
  http://metadb.riken.jp/0001925I129C57BL6Ncoa5tm1HxiaNcoa5Ncoa5Ncoa5tm1Hxia
• insulin resistance_Ncoa5<tm1Hxia>/Ncoa5<+>
  http://metadb.riken.jp/0005331I129C57BL6Ncoa5tm1HxiaNcoa5Ncoa5Ncoa5tm1Hxia