Sarah N. Cilvik, et.al., Fibroblast growth factor receptor 1 signaling in adult cardiomyocytes increases contractility and results in a hypertrophic cardiomyopathy., PloS one, 2013, 8

http://rdf.ncbi.nlm.nih.gov/pubmed/24349409

Sarah N. Cilvik, et.al., Fibroblast growth factor receptor 1 signaling in adult cardiomyocytes increases contractility and results in a hypertrophic cardiomyopathy., PloS one, 2013, 8

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-Fgfr3*R248C/Fgfr1)#Dor
  http://metadb.riken.jp/db/mgi_rdf/MGI:5604241

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• cardiac interstitial fibrosis_Tg(Myh6-rtTA)8585Jam/0,Tg(tetO-Fgfr3*R248C/Fgfr1)#Dor/0
  http://metadb.riken.jp/0005608I129C57BL6FVBNFVBNTacTgMyh6rtTA8585Jam0TgtetOFgfr3R248CFgfr1Dor0TgtetOFgfr3R248CFgfr1DorTgMyh6rtTA8585Jam
• disorganized myocardium_Tg(Myh6-rtTA)8585Jam/0,Tg(tetO-Fgfr3*R248C/Fgfr1)#Dor/0
  http://metadb.riken.jp/0002190I129C57BL6FVBNFVBNTacTgMyh6rtTA8585Jam0TgtetOFgfr3R248CFgfr1Dor0TgtetOFgfr3R248CFgfr1DorTgMyh6rtTA8585Jam
• thick ventricular wall_Tg(Myh6-rtTA)8585Jam/0,Tg(tetO-Fgfr3*R248C/Fgfr1)#Dor/0
  http://metadb.riken.jp/0002953I129C57BL6FVBNFVBNTacTgMyh6rtTA8585Jam0TgtetOFgfr3R248CFgfr1Dor0TgtetOFgfr3R248CFgfr1DorTgMyh6rtTA8585Jam
• abnormal cardiac muscle relaxation_Tg(Myh6-rtTA)8585Jam/0,Tg(tetO-Fgfr3*R248C/Fgfr1)#Dor/0
  http://metadb.riken.jp/0004084I129C57BL6FVBNFVBNTacTgMyh6rtTA8585Jam0TgtetOFgfr3R248CFgfr1Dor0TgtetOFgfr3R248CFgfr1DorTgMyh6rtTA8585Jam
• increased cardiac muscle contractility_Tg(Myh6-rtTA)8585Jam/0,Tg(tetO-Fgfr3*R248C/Fgfr1)#Dor/0
  http://metadb.riken.jp/0005599I129C57BL6FVBNFVBNTacTgMyh6rtTA8585Jam0TgtetOFgfr3R248CFgfr1Dor0TgtetOFgfr3R248CFgfr1DorTgMyh6rtTA8585Jam
• enlarged myocardial fiber_Tg(Myh6-rtTA)8585Jam/0,Tg(tetO-Fgfr3*R248C/Fgfr1)#Dor/0
  http://metadb.riken.jp/0004564I129C57BL6FVBNFVBNTacTgMyh6rtTA8585Jam0TgtetOFgfr3R248CFgfr1Dor0TgtetOFgfr3R248CFgfr1DorTgMyh6rtTA8585Jam
• cardiomyopathy_Tg(Myh6-rtTA)8585Jam/0,Tg(tetO-Fgfr3*R248C/Fgfr1)#Dor/0
  http://metadb.riken.jp/0005330I129C57BL6FVBNFVBNTacTgMyh6rtTA8585Jam0TgtetOFgfr3R248CFgfr1Dor0TgtetOFgfr3R248CFgfr1DorTgMyh6rtTA8585Jam
• enlarged heart_Tg(Myh6-rtTA)8585Jam/0,Tg(tetO-Fgfr3*R248C/Fgfr1)#Dor/0
  http://metadb.riken.jp/0000274I129C57BL6FVBNFVBNTacTgMyh6rtTA8585Jam0TgtetOFgfr3R248CFgfr1Dor0TgtetOFgfr3R248CFgfr1DorTgMyh6rtTA8585Jam
• cardiac hypertrophy_Tg(Myh6-rtTA)8585Jam/0,Tg(tetO-Fgfr3*R248C/Fgfr1)#Dor/0
  http://metadb.riken.jp/0001625I129C57BL6FVBNFVBNTacTgMyh6rtTA8585Jam0TgtetOFgfr3R248CFgfr1Dor0TgtetOFgfr3R248CFgfr1DorTgMyh6rtTA8585Jam
• abnormal cardiovascular system physiology_Tg(Myh6-rtTA)8585Jam/0,Tg(tetO-Fgfr3*R248C/Fgfr1)#Dor/0
  http://metadb.riken.jp/0001544I129C57BL6FVBNFVBNTacTgMyh6rtTA8585Jam0TgtetOFgfr3R248CFgfr1Dor0TgtetOFgfr3R248CFgfr1DorTgMyh6rtTA8585Jam
• heart left ventricle outflow tract stenosis_Tg(Myh6-rtTA)8585Jam/0,Tg(tetO-Fgfr3*R248C/Fgfr1)#Dor/0
  http://metadb.riken.jp/0010448I129C57BL6FVBNFVBNTacTgMyh6rtTA8585Jam0TgtetOFgfr3R248CFgfr1Dor0TgtetOFgfr3R248CFgfr1DorTgMyh6rtTA8585Jam

class

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-Fgfr3*R248C/Fgfr1)#Dor
  http://metadb.riken.jp/db/mgi_rdf/MGI:5604241