Frieda. Chen, et.al., First mouse model for combined osteogenesis imperfecta and Ehlers-Danlos syndrome., Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2014, 29

http://rdf.ncbi.nlm.nih.gov/pubmed/24443344

Frieda. Chen, et.al., First mouse model for combined osteogenesis imperfecta and Ehlers-Danlos syndrome., Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2014, 29

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Col1a1<M1Jrt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5620941

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal osteoblast morphology_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0004986IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• thin body_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0013138IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• thin tail_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0000589IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• decreased bone mineral content_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0010124IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• decreased skin tensile strength_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0003089IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• prenatal lethality, complete penetrance_Col1a1<M1Jrt>/Col1a1<M1Jrt>
  http://metadb.riken.jp/0011091IC3HHeJC57BL6JCol1a1M1JrtCol1a1M1JrtCol1a1M1Jrt
• kyphosis_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0000160IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• abnormal dentin morphology_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0002818IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• decreased body weight_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0001262IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• abnormal bone trabecula morphology_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0010867IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• increased bone trabecular spacing_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0013630IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• decreased bone mineral density_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0000063IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• abnormal tendon collagen fibril morphology_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0011643IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• decreased bone trabecula number_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0010869IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• osteoarthritis_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0003560IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• decreased percent body fat/body weight_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0005459IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• fragile skeleton_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0000061IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• weakness_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0000746IC3HHeJC57BL6JCol1a1M1JrtCol1a1Col1a1Col1a1M1Jrt
• decreased trabecular bone thickness_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0009346IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• abnormal bone collagen fibril morphology_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0011642IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• decreased body size_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0001265IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• increased osteoblast cell number_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0004988IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• abnormal compact bone morphology_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0003797IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• abnormal fertility/fecundity_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0002161IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• abnormal gait_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0001406IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• myocardial hypertrophy_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0010633IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• abnormal femur morphology_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0000559IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• decreased tendon stiffness_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0003098IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• decreased bone strength_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0004991IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• abnormal cutaneous collagen fibril morphology_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0008438IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• abnormal motor coordination/ balance_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0001516IC3HHeJC57BL6JCol1a1M1JrtCol1a1Col1a1Col1a1M1Jrt
• increased bone resorption_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0004992IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• decreased collagen level_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0020254IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• fragile skeleton_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0000061IC3HHeJC57BL6JCol1a1M1JrtCol1a1Col1a1Col1a1M1Jrt
• decreased trabecular bone volume_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0010879IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• abnormal tail movements_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0001391IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• abnormal extracellular matrix morphology_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0013258IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• decreased bone mineral density_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0000063IC3HHeJC57BL6JCol1a1M1JrtCol1a1Col1a1Col1a1M1Jrt
• abnormal bone mineralization_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0002896IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1
• decreased bone trabecular spacing_Col1a1<M1Jrt>/Col1a1<+>
  http://metadb.riken.jp/0013631IC3HHeJC57BL6JFVBNJCol1a1M1JrtCol1a1Col1a1M1JrtCol1a1

class

http://purl.org/net/cito/citesAsAuthority

• Col1a1<M1Jrt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5620941