Su. Yang, et.al., Age-dependent decrease in chaperone activity impairs MANF expression, leading to Purkinje cell degeneration in inducible SCA17 mice., Neuron, 2014, 81

http://rdf.ncbi.nlm.nih.gov/pubmed/24462098

Su. Yang, et.al., Age-dependent decrease in chaperone activity impairs MANF expression, leading to Purkinje cell degeneration in inducible SCA17 mice., Neuron, 2014, 81

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tbp<tm1.1Xjl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5693900

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• kyphosis_Tbp<tm1Xjl>/Tbp<+>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0000160I129SSvEvC57BL6CBATbptm1XjlTbpTgCAGcreEsr15Amc0TgCAGcreEsr15AmcTbpTbptm1Xjl
• short stride length_Tbp<tm1.1Xjl>/Tbp<+>
  http://metadb.riken.jp/0001407I129SSvEvC57BL6JFVBNTbptm11XjlTbpTbpTbptm11Xjl
• impaired balance_Tbp<tm1Xjl>/Tbp<+>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0001525I129SSvEvC57BL6CBATbptm1XjlTbpTgCAGcreEsr15Amc0TgCAGcreEsr15AmcTbpTbptm1Xjl
• thin cerebellar molecular layer_Tbp<tm1Xjl>/Tbp<+>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0000890I129SSvEvC57BL6CBATbptm1XjlTbpTgCAGcreEsr15Amc0TgCAGcreEsr15AmcTbpTbptm1Xjl
• decreased body weight_Tbp<tm1Xjl>/Tbp<+>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0001262I129SSvEvC57BL6CBATbptm1XjlTbpTgCAGcreEsr15Amc0TgCAGcreEsr15AmcTbpTbptm1Xjl
• impaired coordination_Tbp<tm1Xjl>/Tbp<+>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0001405I129SSvEvC57BL6CBATbptm1XjlTbpTgCAGcreEsr15Amc0TgCAGcreEsr15AmcTbpTbptm1Xjl
• premature death_Tbp<tm1Xjl>/Tbp<+>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0002083I129SSvEvC57BL6CBATbptm1XjlTbpTgCAGcreEsr15Amc0TgCAGcreEsr15AmcTbpTbptm1Xjl
• abnormal gait_Tbp<tm1Xjl>/Tbp<+>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0001406I129SSvEvC57BL6CBATbptm1XjlTbpTgCAGcreEsr15Amc0TgCAGcreEsr15AmcTbpTbptm1Xjl
• abnormal Purkinje cell dendrite morphology_Tbp<tm1Xjl>/Tbp<+>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0008572I129SSvEvC57BL6CBATbptm1XjlTbpTgCAGcreEsr15Amc0TgCAGcreEsr15AmcTbpTbptm1Xjl
• ataxia_Tbp<tm1.1Xjl>/Tbp<+>
  http://metadb.riken.jp/0001393I129SSvEvC57BL6JFVBNTbptm11XjlTbpTbpTbptm11Xjl
• Purkinje cell degeneration_Tbp<tm1Xjl>/Tbp<+>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0000876I129SSvEvC57BL6CBATbptm1XjlTbpTgCAGcreEsr15Amc0TgCAGcreEsr15AmcTbpTbptm1Xjl
• short stride length_Tbp<tm1Xjl>/Tbp<+>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0001407I129SSvEvC57BL6CBATbptm1XjlTbpTgCAGcreEsr15Amc0TgCAGcreEsr15AmcTbpTbptm1Xjl
• limb grasping_Tbp<tm1.1Xjl>/Tbp<+>
  http://metadb.riken.jp/0001513I129SSvEvC57BL6JFVBNTbptm11XjlTbpTbpTbptm11Xjl

class

http://purl.org/net/cito/citesAsAuthority

• Tbp<tm1.1Xjl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5693900