Akiko. Nagamachi, et.al., Acquired deficiency of A20 results in rapid apoptosis, systemic inflammation, and abnormal hematopoietic stem cell function., PloS one, 2014, 9

http://rdf.ncbi.nlm.nih.gov/pubmed/24498102

Akiko. Nagamachi, et.al., Acquired deficiency of A20 results in rapid apoptosis, systemic inflammation, and abnormal hematopoietic stem cell function., PloS one, 2014, 9

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tnfaip3<tm1Homy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5621002

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• enlarged liver_Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0000599I129S6SvEvTacC57BL6JCBAJTnfaip3tm1HomyTnfaip3tm1HomyTgMx1cre1CgnTgMx1cre1CgnTnfaip3tm1Homy
• abnormal spleen morphology_Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0000689I129S6SvEvTacC57BL6JCBAJTnfaip3tm1HomyTnfaip3tm1HomyTgMx1cre1CgnTgMx1cre1CgnTnfaip3tm1Homy
• abnormal circulating interleukin level_Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/?,Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>
  http://metadb.riken.jp/0008588I129S6SvEvTacC57BL6JC57BL6NTacGtROSA26Sortm9creESR1ArteTnfaip3tm1HomyTnfaip3tm1HomyGtROSA26Sortm9creESR1ArteTnfaip3tm1Homy
• abnormal B cell number_Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0002458I129S6SvEvTacC57BL6JCBAJTnfaip3tm1HomyTnfaip3tm1HomyTgMx1cre1CgnTgMx1cre1CgnTnfaip3tm1Homy
• abnormal circulating cytokine level_Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/?,Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>
  http://metadb.riken.jp/0010210I129S6SvEvTacC57BL6JC57BL6NTacGtROSA26Sortm9creESR1ArteTnfaip3tm1HomyTnfaip3tm1HomyGtROSA26Sortm9creESR1ArteTnfaip3tm1Homy
• cachexia_Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0005150I129S6SvEvTacC57BL6JCBAJTnfaip3tm1HomyTnfaip3tm1HomyTgMx1cre1CgnTgMx1cre1CgnTnfaip3tm1Homy
• increased circulating interleukin-1 beta level_Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/?,Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>
  http://metadb.riken.jp/0008641I129S6SvEvTacC57BL6JC57BL6NTacGtROSA26Sortm9creESR1ArteTnfaip3tm1HomyTnfaip3tm1HomyGtROSA26Sortm9creESR1ArteTnfaip3tm1Homy
• abnormal blood cell morphology/development_Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/?,Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>
  http://metadb.riken.jp/0002429I129S6SvEvTacC57BL6JC57BL6NTacGtROSA26Sortm9creESR1ArteTnfaip3tm1HomyTnfaip3tm1HomyGtROSA26Sortm9creESR1ArteTnfaip3tm1Homy
• enlarged lymph nodes_Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0000702I129S6SvEvTacC57BL6JCBAJTnfaip3tm1HomyTnfaip3tm1HomyTgMx1cre1CgnTgMx1cre1CgnTnfaip3tm1Homy
• anemia_Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0001577I129S6SvEvTacC57BL6JCBAJTnfaip3tm1HomyTnfaip3tm1HomyTgMx1cre1CgnTgMx1cre1CgnTnfaip3tm1Homy
• increased circulating interleukin-6 level_Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0008596I129S6SvEvTacC57BL6JCBAJTnfaip3tm1HomyTnfaip3tm1HomyTgMx1cre1CgnTgMx1cre1CgnTnfaip3tm1Homy
• pale spleen_Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/?,Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>
  http://metadb.riken.jp/0009246I129S6SvEvTacC57BL6JC57BL6NTacGtROSA26Sortm9creESR1ArteTnfaip3tm1HomyTnfaip3tm1HomyGtROSA26Sortm9creESR1ArteTnfaip3tm1Homy
• lung inflammation_Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0001861I129S6SvEvTacC57BL6JCBAJTnfaip3tm1HomyTnfaip3tm1HomyTgMx1cre1CgnTgMx1cre1CgnTnfaip3tm1Homy
• increased sensitivity to xenobiotic induced morbidity/mortality_Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/?,Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>
  http://metadb.riken.jp/0009766I129S6SvEvTacC57BL6JC57BL6NTacGtROSA26Sortm9creESR1ArteTnfaip3tm1HomyTnfaip3tm1HomyGtROSA26Sortm9creESR1ArteTnfaip3tm1Homy
• liver inflammation_Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0001860I129S6SvEvTacC57BL6JCBAJTnfaip3tm1HomyTnfaip3tm1HomyTgMx1cre1CgnTgMx1cre1CgnTnfaip3tm1Homy
• increased circulating interferon-gamma level_Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/?,Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>
  http://metadb.riken.jp/0008577I129S6SvEvTacC57BL6JC57BL6NTacGtROSA26Sortm9creESR1ArteTnfaip3tm1HomyTnfaip3tm1HomyGtROSA26Sortm9creESR1ArteTnfaip3tm1Homy
• increased circulating tumor necrosis factor level_Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0008553I129S6SvEvTacC57BL6JCBAJTnfaip3tm1HomyTnfaip3tm1HomyTgMx1cre1CgnTgMx1cre1CgnTnfaip3tm1Homy
• increased circulating interleukin-6 level_Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/?,Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>
  http://metadb.riken.jp/0008596I129S6SvEvTacC57BL6JC57BL6NTacGtROSA26Sortm9creESR1ArteTnfaip3tm1HomyTnfaip3tm1HomyGtROSA26Sortm9creESR1ArteTnfaip3tm1Homy
• abnormal liver morphology_Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/?,Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>
  http://metadb.riken.jp/0000598I129S6SvEvTacC57BL6JC57BL6NTacGtROSA26Sortm9creESR1ArteTnfaip3tm1HomyTnfaip3tm1HomyGtROSA26Sortm9creESR1ArteTnfaip3tm1Homy
• thymus atrophy_Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/?,Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>
  http://metadb.riken.jp/0003644I129S6SvEvTacC57BL6JC57BL6NTacGtROSA26Sortm9creESR1ArteTnfaip3tm1HomyTnfaip3tm1HomyGtROSA26Sortm9creESR1ArteTnfaip3tm1Homy
• abnormal blood cell morphology/development_Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0002429I129S6SvEvTacC57BL6JCBAJTnfaip3tm1HomyTnfaip3tm1HomyTgMx1cre1CgnTgMx1cre1CgnTnfaip3tm1Homy
• increased circulating interleukin-1 beta level_Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0008641I129S6SvEvTacC57BL6JCBAJTnfaip3tm1HomyTnfaip3tm1HomyTgMx1cre1CgnTgMx1cre1CgnTnfaip3tm1Homy
• increased apoptosis_Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/?,Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>
  http://metadb.riken.jp/0006042I129S6SvEvTacC57BL6JC57BL6NTacGtROSA26Sortm9creESR1ArteTnfaip3tm1HomyTnfaip3tm1HomyGtROSA26Sortm9creESR1ArteTnfaip3tm1Homy
• abnormal myelopoiesis_Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0001601I129S6SvEvTacC57BL6JCBAJTnfaip3tm1HomyTnfaip3tm1HomyTgMx1cre1CgnTgMx1cre1CgnTnfaip3tm1Homy
• premature death_Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0002083I129S6SvEvTacC57BL6JCBAJTnfaip3tm1HomyTnfaip3tm1HomyTgMx1cre1CgnTgMx1cre1CgnTnfaip3tm1Homy
• abnormal circulating cytokine level_Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0010210I129S6SvEvTacC57BL6JCBAJTnfaip3tm1HomyTnfaip3tm1HomyTgMx1cre1CgnTgMx1cre1CgnTnfaip3tm1Homy
• abnormal circulating interleukin level_Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0008588I129S6SvEvTacC57BL6JCBAJTnfaip3tm1HomyTnfaip3tm1HomyTgMx1cre1CgnTgMx1cre1CgnTnfaip3tm1Homy
• increased circulating interferon-gamma level_Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0008577I129S6SvEvTacC57BL6JCBAJTnfaip3tm1HomyTnfaip3tm1HomyTgMx1cre1CgnTgMx1cre1CgnTnfaip3tm1Homy
• increased circulating tumor necrosis factor level_Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/?,Tnfaip3<tm1Homy>/Tnfaip3<tm1Homy>
  http://metadb.riken.jp/0008553I129S6SvEvTacC57BL6JC57BL6NTacGtROSA26Sortm9creESR1ArteTnfaip3tm1HomyTnfaip3tm1HomyGtROSA26Sortm9creESR1ArteTnfaip3tm1Homy

class

http://purl.org/net/cito/citesAsAuthority

• Tnfaip3<tm1Homy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5621002

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]
• [Blank]

BRC マウスの系統

http://purl.org/net/cito/citesAsAuthority

• B6;129P2-Tnfaip3<tm1.1Homy>
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC05495
• B6;129P2-Tnfaip3<tm1Homy>
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC05494

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]
• [Blank]