Wenbin. Wang, et.al., Genetic activation of ERK5 MAP kinase enhances adult neurogenesis and extends hippocampus-dependent long-term memory., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, 34

http://rdf.ncbi.nlm.nih.gov/pubmed/24501354

Wenbin. Wang, et.al., Genetic activation of ERK5 MAP kinase enhances adult neurogenesis and extends hippocampus-dependent long-term memory., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, 34

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(ACTB-Map2k5*/EGFP)Zxi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5605718

class

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(ACTB-Map2k5*/EGFP)Zxi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5605718

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal spatial reference memory_Gt(ROSA)26Sor<tm1(ACTB-Map2k5*/EGFP)Zxi>/Gt(ROSA)26Sor<tm1(ACTB-Map2k5*/EGFP)Zxi>,Tg(Nes-cre/Esr1*)4Ynj/0
  http://metadb.riken.jp/0008414I129S6SvEvTacC57BL6NCrGtROSA26Sortm1ACTBMap2k5EGFPZxiGtROSA26Sortm1ACTBMap2k5EGFPZxiTgNescreEsr14Ynj0TgNescreEsr14YnjGtROSA26Sortm1ACTBMap2k5EGFPZxi
• abnormal dendritic spine morphology_Gt(ROSA)26Sor<tm1(ACTB-Map2k5*/EGFP)Zxi>/Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>,Tg(Nes-cre/Esr1*)4Ynj/0
  http://metadb.riken.jp/0009936I129S6SvEvTacC57BL6NCrGtROSA26Sortm1ACTBMap2k5EGFPZxiGtROSA26Sortm14CAGtdTomatoHzeTgNescreEsr14Ynj0GtROSA26Sortm1ACTBMap2k5EGFPZxiGtROSA26Sortm14CAGtdTomatoHzeTgNescreEsr14Ynj
• abnormal long term object recognition memory_Gt(ROSA)26Sor<tm1(ACTB-Map2k5*/EGFP)Zxi>/Gt(ROSA)26Sor<tm1(ACTB-Map2k5*/EGFP)Zxi>,Tg(Nes-cre/Esr1*)4Ynj/0
  http://metadb.riken.jp/0002801I129S6SvEvTacC57BL6NCrGtROSA26Sortm1ACTBMap2k5EGFPZxiGtROSA26Sortm1ACTBMap2k5EGFPZxiTgNescreEsr14Ynj0TgNescreEsr14YnjGtROSA26Sortm1ACTBMap2k5EGFPZxi
• abnormal dendrite morphology_Gt(ROSA)26Sor<tm1(ACTB-Map2k5*/EGFP)Zxi>/Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>,Tg(Nes-cre/Esr1*)4Ynj/0
  http://metadb.riken.jp/0008143I129S6SvEvTacC57BL6NCrGtROSA26Sortm1ACTBMap2k5EGFPZxiGtROSA26Sortm14CAGtdTomatoHzeTgNescreEsr14Ynj0GtROSA26Sortm1ACTBMap2k5EGFPZxiGtROSA26Sortm14CAGtdTomatoHzeTgNescreEsr14Ynj
• abnormal neuron physiology_Gt(ROSA)26Sor<tm1(ACTB-Map2k5*/EGFP)Zxi>/Gt(ROSA)26Sor<tm1(ACTB-Map2k5*/EGFP)Zxi>,Tg(Nes-cre/Esr1*)4Ynj/0
  http://metadb.riken.jp/0004811I129S6SvEvTacC57BL6NCrGtROSA26Sortm1ACTBMap2k5EGFPZxiGtROSA26Sortm1ACTBMap2k5EGFPZxiTgNescreEsr14Ynj0TgNescreEsr14YnjGtROSA26Sortm1ACTBMap2k5EGFPZxi
• enhanced spatial learning_Gt(ROSA)26Sor<tm1(ACTB-Map2k5*/EGFP)Zxi>/Gt(ROSA)26Sor<tm1(ACTB-Map2k5*/EGFP)Zxi>,Tg(Nes-cre/Esr1*)4Ynj/0
  http://metadb.riken.jp/0012306I129S6SvEvTacC57BL6NCrGtROSA26Sortm1ACTBMap2k5EGFPZxiGtROSA26Sortm1ACTBMap2k5EGFPZxiTgNescreEsr14Ynj0TgNescreEsr14YnjGtROSA26Sortm1ACTBMap2k5EGFPZxi
• abnormal dentate gyrus morphology_Gt(ROSA)26Sor<tm1(ACTB-Map2k5*/EGFP)Zxi>/Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>,Tg(Nes-cre/Esr1*)4Ynj/0
  http://metadb.riken.jp/0000812I129S6SvEvTacC57BL6NCrGtROSA26Sortm1ACTBMap2k5EGFPZxiGtROSA26Sortm14CAGtdTomatoHzeTgNescreEsr14Ynj0GtROSA26Sortm1ACTBMap2k5EGFPZxiGtROSA26Sortm14CAGtdTomatoHzeTgNescreEsr14Ynj
• abnormal dentate gyrus morphology_Gt(ROSA)26Sor<tm1(ACTB-Map2k5*/EGFP)Zxi>/Gt(ROSA)26Sor<tm1(ACTB-Map2k5*/EGFP)Zxi>,Tg(Nes-cre/Esr1*)4Ynj/0
  http://metadb.riken.jp/0000812I129S6SvEvTacC57BL6NCrGtROSA26Sortm1ACTBMap2k5EGFPZxiGtROSA26Sortm1ACTBMap2k5EGFPZxiTgNescreEsr14Ynj0TgNescreEsr14YnjGtROSA26Sortm1ACTBMap2k5EGFPZxi
• abnormal long term spatial reference memory_Gt(ROSA)26Sor<tm1(ACTB-Map2k5*/EGFP)Zxi>/Gt(ROSA)26Sor<tm1(ACTB-Map2k5*/EGFP)Zxi>,Tg(Nes-cre/Esr1*)4Ynj/0
  http://metadb.riken.jp/0008432I129S6SvEvTacC57BL6NCrGtROSA26Sortm1ACTBMap2k5EGFPZxiGtROSA26Sortm1ACTBMap2k5EGFPZxiTgNescreEsr14Ynj0TgNescreEsr14YnjGtROSA26Sortm1ACTBMap2k5EGFPZxi