Haiyan. Qiu, et.al., ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects., The Journal of clinical investigation, 2014, 124

http://rdf.ncbi.nlm.nih.gov/pubmed/24509083

Haiyan. Qiu, et.al., ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects., The Journal of clinical investigation, 2014, 124

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Prnp-FUS*R521C)3313Ejh
  http://metadb.riken.jp/db/mgi_rdf/MGI:5618414

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• premature death_Tg(Prnp-FUS*R521C)3313Ejh/0
  http://metadb.riken.jp/0002083IC57BL6SJLTgPrnpFUSR521C3313Ejh0TgPrnpFUSR521C3313Ejh
• abnormal gait_Tg(Prnp-FUS*R521C)3313Ejh/0
  http://metadb.riken.jp/0001406IC57BL6SJLTgPrnpFUSR521C3313Ejh0TgPrnpFUSR521C3313Ejh
• abnormal dendritic spine morphology_Tg(Prnp-FUS*R521C)3313Ejh/0
  http://metadb.riken.jp/0009936IC57BL6SJLTgPrnpFUSR521C3313Ejh0TgPrnpFUSR521C3313Ejh
• neurodegeneration_Tg(Prnp-FUS*R521C)3313Ejh/0
  http://metadb.riken.jp/0002229IC57BL6SJLTgPrnpFUSR521C3313Ejh0TgPrnpFUSR521C3313Ejh
• decreased motor neuron number_Tg(Prnp-FUS*R521C)3313Ejh/0
  http://metadb.riken.jp/0000939IC57BL6SJLTgPrnpFUSR521C3313Ejh0TgPrnpFUSR521C3313Ejh
• abnormal motor learning_Tg(Prnp-FUS*R521C)3313Ejh/0
  http://metadb.riken.jp/0002804IC57BL6SJLTgPrnpFUSR521C3313Ejh0TgPrnpFUSR521C3313Ejh
• muscle degeneration_Tg(Prnp-FUS*R521C)3313Ejh/0
  http://metadb.riken.jp/0000749IC57BL6SJLTgPrnpFUSR521C3313Ejh0TgPrnpFUSR521C3313Ejh
• abnormal dendrite morphology_Tg(Prnp-FUS*R521C)3313Ejh/0
  http://metadb.riken.jp/0008143IC57BL6SJLTgPrnpFUSR521C3313Ejh0TgPrnpFUSR521C3313Ejh
• limb grasping_Tg(Prnp-FUS*R521C)3313Ejh/0
  http://metadb.riken.jp/0001513IC57BL6SJLTgPrnpFUSR521C3313Ejh0TgPrnpFUSR521C3313Ejh
• abnormal motor coordination/ balance_Tg(Prnp-FUS*R521C)3313Ejh/0
  http://metadb.riken.jp/0001516IC57BL6SJLTgPrnpFUSR521C3313Ejh0TgPrnpFUSR521C3313Ejh
• motor neuron degeneration_Tg(Prnp-FUS*R521C)3313Ejh/0
  http://metadb.riken.jp/0000938IC57BL6SJLTgPrnpFUSR521C3313Ejh0TgPrnpFUSR521C3313Ejh
• postnatal growth retardation_Tg(Prnp-FUS*R521C)3313Ejh/0
  http://metadb.riken.jp/0001732IC57BL6SJLTgPrnpFUSR521C3313Ejh0TgPrnpFUSR521C3313Ejh
• spasticity_Tg(Prnp-FUS*R521C)3313Ejh/0
  http://metadb.riken.jp/0012051IC57BL6SJLTgPrnpFUSR521C3313Ejh0TgPrnpFUSR521C3313Ejh
• abnormal neuromuscular synapse morphology_Tg(Prnp-FUS*R521C)3313Ejh/0
  http://metadb.riken.jp/0001053IC57BL6SJLTgPrnpFUSR521C3313Ejh0TgPrnpFUSR521C3313Ejh
• abnormal cell physiology_Tg(Prnp-FUS*R521C)3313Ejh/0
  http://metadb.riken.jp/0005621IC57BL6SJLTgPrnpFUSR521C3313Ejh0TgPrnpFUSR521C3313Ejh
• hindlimb paralysis_Tg(Prnp-FUS*R521C)3313Ejh/0
  http://metadb.riken.jp/0000755IC57BL6SJLTgPrnpFUSR521C3313Ejh0TgPrnpFUSR521C3313Ejh

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Prnp-FUS*R521C)3313Ejh
  http://metadb.riken.jp/db/mgi_rdf/MGI:5618414