Safak. Caglayan, et.al., Lysosomal sorting of amyloid-β by the SORLA receptor is impaired by a familial Alzheimer's disease mutation., Science translational medicine, 2014, 6

http://rdf.ncbi.nlm.nih.gov/pubmed/24523320

Safak. Caglayan, et.al., Lysosomal sorting of amyloid-β by the SORLA receptor is impaired by a familial Alzheimer's disease mutation., Science translational medicine, 2014, 6

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm3.1(CAG-SORL1)Tew>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5586989

class

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm3.1(CAG-SORL1)Tew>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5586989

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased survivor rate_Gt(ROSA)26Sor<tm3.1(CAG-SORL1)Tew>/Gt(ROSA)26Sor<tm3.1(CAG-SORL1)Tew>
  http://metadb.riken.jp/0008770NSGtROSA26Sortm31CAGSORL1TewGtROSA26Sortm31CAGSORL1TewGtROSA26Sortm31CAGSORL1Tew
• abnormal nervous system morphology_Gt(ROSA)26Sor<tm3.1(CAG-SORL1)Tew>/Gt(ROSA)26Sor<+>,Tg(APPV717F)109Ili/0
  http://metadb.riken.jp/0003632NSGtROSA26Sortm31CAGSORL1TewGtROSA26SorTgAPPV717F109Ili0GtROSA26Sortm31CAGSORL1TewTgAPPV717F109IliGtROSA26Sor
• abnormal nervous system morphology_Gt(ROSA)26Sor<tm3.1(CAG-SORL1)Tew>/Gt(ROSA)26Sor<tm3.1(CAG-SORL1)Tew>
  http://metadb.riken.jp/0003632NSGtROSA26Sortm31CAGSORL1TewGtROSA26Sortm31CAGSORL1TewGtROSA26Sortm31CAGSORL1Tew
• abnormal nervous system morphology_Gt(ROSA)26Sor<tm3.1(CAG-SORL1)Tew>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0003632NSGtROSA26Sortm31CAGSORL1TewGtROSA26SorGtROSA26SorGtROSA26Sortm31CAGSORL1Tew
• perinatal lethality, incomplete penetrance_Gt(ROSA)26Sor<tm3.1(CAG-SORL1)Tew>/Gt(ROSA)26Sor<tm3.1(CAG-SORL1)Tew>
  http://metadb.riken.jp/0011090NSGtROSA26Sortm31CAGSORL1TewGtROSA26Sortm31CAGSORL1TewGtROSA26Sortm31CAGSORL1Tew