Masahide. Funabiki, et.al., Autoimmune disorders associated with gain of function of the intracellular sensor MDA5., Immunity, 2014, 40

http://rdf.ncbi.nlm.nih.gov/pubmed/24530055

Masahide. Funabiki, et.al., Autoimmune disorders associated with gain of function of the intracellular sensor MDA5., Immunity, 2014, 40

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ifih1<Rgsc422>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5617217

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• glomerulonephritis_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0002743D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• abnormal macrophage activation involved in immune response_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0011075D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• increased IgG level_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0002493D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• increased IgM level_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0002494D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• increased granulocyte number_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0000322D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• increased plasma cell number_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0008097D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• increased dendritic cell number_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0008126D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• increased IgA level_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0002495D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• postnatal growth retardation_Ifih1<Rgsc422>/Ifih1<Rgsc422>
  http://metadb.riken.jp/0001732D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Rgsc422Ifih1Rgsc422
• abnormal chemokine level_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0008721D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• decreased survivor rate_Ifih1<Rgsc422>/Ifih1<Rgsc422>
  http://metadb.riken.jp/0008770D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Rgsc422Ifih1Rgsc422
• glomerulonephritis_Ifih1<Rgsc422>/Ifih1<+>,Mavs<tm1Aki>/Mavs<+>
  http://metadb.riken.jp/0002743IC57BL6JJclDBA2JJclIfih1Rgsc422Ifih1Mavstm1AkiMavsMavsIfih1Ifih1Rgsc422Mavstm1Aki
• increased susceptibility to systemic lupus erythematosus_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0004801D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• postnatal lethality_Ifih1<Rgsc422>/Ifih1<Rgsc422>
  http://metadb.riken.jp/0002082D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Rgsc422Ifih1Rgsc422
• increased inflammatory response_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0001846D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• increased susceptibility to systemic lupus erythematosus_Ifih1<Rgsc422>/Ifih1<Rgsc422>
  http://metadb.riken.jp/0004801D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Rgsc422Ifih1Rgsc422
• autoimmune response_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0001844D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• decreased survivor rate_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0008770D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• abnormal leukocyte cell number_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0000217D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• skin inflammation_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0004947D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• abnormal T cell activation_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0001828D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• increased anti-nuclear antigen antibody level_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0004794D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• increased macrophage cell number_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0005425D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• glomerulonephritis_Ifih1<Rgsc422>/Ifih1<+>,Ifnar1<tm1Agt>/Ifnar1<+>
  http://metadb.riken.jp/0002743I129S2SvPasC57BL6JJclDBA2JJclIfih1Rgsc422Ifih1Ifnar1tm1AgtIfnar1Ifnar1tm1AgtIfih1Rgsc422Ifih1Ifnar1
• postnatal growth retardation_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0001732D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• liver inflammation_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0001860D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• glomerulonephritis_Ifih1<Rgsc422>/Ifih1<Rgsc422>
  http://metadb.riken.jp/0002743D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Rgsc422Ifih1Rgsc422
• mixed cellular infiltration to dermis_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0001246D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• abnormal cytokine level_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0008713D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• increased anti-double stranded DNA antibody level_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0004762D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• abnormal dendritic cell antigen presentation_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0002455D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422
• increased immunoglobulin level_Ifih1<Rgsc422>/Ifih1<+>
  http://metadb.riken.jp/0002461D2JJclB6JJclIfih1Rgsc422Ifih1Rgsc422Ifih1Ifih1Ifih1Rgsc422

class

http://purl.org/net/cito/citesAsAuthority

• Ifih1<Rgsc422>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5617217