Aditya. Murthy, et.al., A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3., Nature, 2014, 506

http://rdf.ncbi.nlm.nih.gov/pubmed/24553140

Aditya. Murthy, et.al., A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3., Nature, 2014, 506

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Atg16l1<tm2.1Mvlc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5605965
• Atg16l1<tm1.1Mvlc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5605964

class

http://purl.org/net/cito/citesAsAuthority

• Atg16l1<tm2.1Mvlc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5605965
• Atg16l1<tm1.1Mvlc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5605964

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal macrophage physiology_Atg16l1<tm1.1Mvlc>/Atg16l1<tm1.1Mvlc>
  http://metadb.riken.jp/0002451C57BL6Atg16l1tm11MvlcAtg16l1tm11MvlcAtg16l1tm11MvlcAtg16l1tm11Mvlc
• abnormal autophagy_Atg16l1<tm1.1Mvlc>/Atg16l1<tm1.1Mvlc>
  http://metadb.riken.jp/0008260C57BL6Atg16l1tm11MvlcAtg16l1tm11MvlcAtg16l1tm11MvlcAtg16l1tm11Mvlc
• increased macrophage cytokine production_Atg16l1<tm1.1Mvlc>/Atg16l1<tm1.1Mvlc>
  http://metadb.riken.jp/0011078C57BL6Atg16l1tm11MvlcAtg16l1tm11MvlcAtg16l1tm11MvlcAtg16l1tm11Mvlc
• increased circulating interleukin-1 beta level_Atg16l1<tm1.1Mvlc>/Atg16l1<tm1.1Mvlc>
  http://metadb.riken.jp/0008641C57BL6Atg16l1tm11MvlcAtg16l1tm11MvlcAtg16l1tm11MvlcAtg16l1tm11Mvlc
• increased susceptibility to bacterial infection_Atg16l1<tm1.1Mvlc>/Atg16l1<tm1.1Mvlc>
  http://metadb.riken.jp/0002412C57BL6Atg16l1tm11MvlcAtg16l1tm11MvlcAtg16l1tm11MvlcAtg16l1tm11Mvlc
• abnormal autophagy_Atg16l1<tm2.1Mvlc>/Atg16l1<tm2.1Mvlc>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0008260I129P2OlaHsdC57BL6Atg16l1tm21MvlcAtg16l1tm21MvlcLyz2tm1creIfoLyz2Lyz2tm1creIfoLyz2Atg16l1tm21Mvlc