Mirjam. Geibel, et.al., Ablation of TrkB signalling in CCK neurons results in hypercortisolism and obesity., Nature communications, 2014, 5

http://rdf.ncbi.nlm.nih.gov/pubmed/24619096

Mirjam. Geibel, et.al., Ablation of TrkB signalling in CCK neurons results in hypercortisolism and obesity., Nature communications, 2014, 5

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Cck-cre,-lacZ)1Mini
  http://metadb.riken.jp/db/mgi_rdf/MGI:5574585

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal circadian rhythm_Ntrk2<tm2Kln>/Ntrk2<tm2Kln>,Tg(Cck-cre,-lacZ)1Mini/0
  http://metadb.riken.jp/0001502I129S2SvPasC57BL6CBANtrk2tm2KlnNtrk2tm2KlnTgCckcrelacZ1Mini0Ntrk2tm2KlnTgCckcrelacZ1Mini
• increased circulating adrenocorticotropin level_Ntrk2<tm1Mini>/Ntrk2<+>
  http://metadb.riken.jp/0001748I129P2OlaHsdC57BL6Ntrk2tm1MiniNtrk2Ntrk2tm1MiniNtrk2
• increased circulating insulin level_Ntrk2<tm2Kln>/Ntrk2<tm2Kln>,Tg(Cck-cre,-lacZ)1Mini/0
  http://metadb.riken.jp/0002079I129S2SvPasC57BL6CBANtrk2tm2KlnNtrk2tm2KlnTgCckcrelacZ1Mini0Ntrk2tm2KlnTgCckcrelacZ1Mini
• abnormal adipose tissue distribution_Ntrk2<tm2Kln>/Ntrk2<tm2Kln>,Tg(Cck-cre,-lacZ)1Mini/0
  http://metadb.riken.jp/0000013I129S2SvPasC57BL6CBANtrk2tm2KlnNtrk2tm2KlnTgCckcrelacZ1Mini0Ntrk2tm2KlnTgCckcrelacZ1Mini
• increased circulating insulin level_Ntrk2<tm1Mini>/Ntrk2<+>
  http://metadb.riken.jp/0002079I129P2OlaHsdC57BL6Ntrk2tm1MiniNtrk2Ntrk2tm1MiniNtrk2
• increased circulating leptin level_Ntrk2<tm2Kln>/Ntrk2<tm2Kln>,Tg(Cck-cre,-lacZ)1Mini/0
  http://metadb.riken.jp/0005669I129S2SvPasC57BL6CBANtrk2tm2KlnNtrk2tm2KlnTgCckcrelacZ1Mini0Ntrk2tm2KlnTgCckcrelacZ1Mini
• increased liver weight_Ntrk2<tm2Kln>/Ntrk2<tm2Kln>,Tg(Cck-cre,-lacZ)1Mini/0
  http://metadb.riken.jp/0002981I129S2SvPasC57BL6CBANtrk2tm2KlnNtrk2tm2KlnTgCckcrelacZ1Mini0Ntrk2tm2KlnTgCckcrelacZ1Mini
• abnormal GABAergic neuron physiology_Ntrk2<tm2Kln>/Ntrk2<tm2Kln>,Tg(Cck-cre,-lacZ)1Mini/0
  http://metadb.riken.jp/0011987I129S2SvPasC57BL6CBANtrk2tm2KlnNtrk2tm2KlnTgCckcrelacZ1Mini0Ntrk2tm2KlnTgCckcrelacZ1Mini
• abnormal liver morphology_Ntrk2<tm1Mini>/Ntrk2<+>
  http://metadb.riken.jp/0000598I129P2OlaHsdC57BL6Ntrk2tm1MiniNtrk2Ntrk2tm1MiniNtrk2
• increased abdominal fat pad weight_Ntrk2<tm2Kln>/Ntrk2<tm2Kln>,Tg(Cck-cre,-lacZ)1Mini/0
  http://metadb.riken.jp/0009286I129S2SvPasC57BL6CBANtrk2tm2KlnNtrk2tm2KlnTgCckcrelacZ1Mini0Ntrk2tm2KlnTgCckcrelacZ1Mini
• increased susceptibility to age related obesity_Ntrk2<tm1Mini>/Ntrk2<+>
  http://metadb.riken.jp/0003212I129P2OlaHsdC57BL6Ntrk2tm1MiniNtrk2Ntrk2tm1MiniNtrk2
• increased susceptibility to weight gain_Ntrk2<tm2Kln>/Ntrk2<tm2Kln>,Tg(Cck-cre,-lacZ)1Mini/0
  http://metadb.riken.jp/0005455I129S2SvPasC57BL6CBANtrk2tm2KlnNtrk2tm2KlnTgCckcrelacZ1Mini0Ntrk2tm2KlnTgCckcrelacZ1Mini
• abnormal adrenal gland zona fasciculata morphology_Ntrk2<tm2Kln>/Ntrk2<tm2Kln>,Tg(Cck-cre,-lacZ)1Mini/0
  http://metadb.riken.jp/0008294I129S2SvPasC57BL6CBANtrk2tm2KlnNtrk2tm2KlnTgCckcrelacZ1Mini0Ntrk2tm2KlnTgCckcrelacZ1Mini
• abnormal adrenal gland zona fasciculata morphology_Ntrk2<tm1Mini>/Ntrk2<+>
  http://metadb.riken.jp/0008294I129P2OlaHsdC57BL6Ntrk2tm1MiniNtrk2Ntrk2tm1MiniNtrk2
• impaired glucose tolerance_Ntrk2<tm2Kln>/Ntrk2<tm2Kln>,Tg(Cck-cre,-lacZ)1Mini/0
  http://metadb.riken.jp/0005293I129S2SvPasC57BL6CBANtrk2tm2KlnNtrk2tm2KlnTgCckcrelacZ1Mini0Ntrk2tm2KlnTgCckcrelacZ1Mini
• increased circulating leptin level_Ntrk2<tm1Mini>/Ntrk2<+>
  http://metadb.riken.jp/0005669I129P2OlaHsdC57BL6Ntrk2tm1MiniNtrk2Ntrk2tm1MiniNtrk2
• increased abdominal fat pad weight_Ntrk2<tm1Mini>/Ntrk2<+>
  http://metadb.riken.jp/0009286I129P2OlaHsdC57BL6Ntrk2tm1MiniNtrk2Ntrk2tm1MiniNtrk2
• abnormal lipid level_Ntrk2<tm2Kln>/Ntrk2<tm2Kln>,Tg(Cck-cre,-lacZ)1Mini/0
  http://metadb.riken.jp/0001547I129S2SvPasC57BL6CBANtrk2tm2KlnNtrk2tm2KlnTgCckcrelacZ1Mini0Ntrk2tm2KlnTgCckcrelacZ1Mini
• increased gonadal fat pad weight_Ntrk2<tm2Kln>/Ntrk2<tm2Kln>,Tg(Cck-cre,-lacZ)1Mini/0
  http://metadb.riken.jp/0009285I129S2SvPasC57BL6CBANtrk2tm2KlnNtrk2tm2KlnTgCckcrelacZ1Mini0Ntrk2tm2KlnTgCckcrelacZ1Mini
• adrenal cortical hyperplasia_Ntrk2<tm2Kln>/Ntrk2<tm2Kln>,Tg(Cck-cre,-lacZ)1Mini/0
  http://metadb.riken.jp/0008299I129S2SvPasC57BL6CBANtrk2tm2KlnNtrk2tm2KlnTgCckcrelacZ1Mini0Ntrk2tm2KlnTgCckcrelacZ1Mini
• increased total body fat amount_Ntrk2<tm2Kln>/Ntrk2<tm2Kln>,Tg(Cck-cre,-lacZ)1Mini/0
  http://metadb.riken.jp/0010024I129S2SvPasC57BL6CBANtrk2tm2KlnNtrk2tm2KlnTgCckcrelacZ1Mini0Ntrk2tm2KlnTgCckcrelacZ1Mini
• increased body weight_Ntrk2<tm2Kln>/Ntrk2<tm2Kln>,Tg(Cck-cre,-lacZ)1Mini/0
  http://metadb.riken.jp/0001260I129S2SvPasC57BL6CBANtrk2tm2KlnNtrk2tm2KlnTgCckcrelacZ1Mini0Ntrk2tm2KlnTgCckcrelacZ1Mini
• abnormal circulating corticosterone level_Ntrk2<tm2Kln>/Ntrk2<tm2Kln>,Tg(Cck-cre,-lacZ)1Mini/0
  http://metadb.riken.jp/0005345I129S2SvPasC57BL6CBANtrk2tm2KlnNtrk2tm2KlnTgCckcrelacZ1Mini0Ntrk2tm2KlnTgCckcrelacZ1Mini
• increased susceptibility to age related obesity_Ntrk2<tm2Kln>/Ntrk2<tm2Kln>,Tg(Cck-cre,-lacZ)1Mini/0
  http://metadb.riken.jp/0003212I129S2SvPasC57BL6CBANtrk2tm2KlnNtrk2tm2KlnTgCckcrelacZ1Mini0Ntrk2tm2KlnTgCckcrelacZ1Mini
• adrenal cortical hyperplasia_Ntrk2<tm1Mini>/Ntrk2<+>
  http://metadb.riken.jp/0008299I129P2OlaHsdC57BL6Ntrk2tm1MiniNtrk2Ntrk2tm1MiniNtrk2
• hepatic steatosis_Ntrk2<tm2Kln>/Ntrk2<tm2Kln>,Tg(Cck-cre,-lacZ)1Mini/0
  http://metadb.riken.jp/0002628I129S2SvPasC57BL6CBANtrk2tm2KlnNtrk2tm2KlnTgCckcrelacZ1Mini0Ntrk2tm2KlnTgCckcrelacZ1Mini

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Cck-cre,-lacZ)1Mini
  http://metadb.riken.jp/db/mgi_rdf/MGI:5574585