Tracy A. Brennan, et.al., Mouse models of telomere dysfunction phenocopy skeletal changes found in human age-related osteoporosis., Disease models & mechanisms, 2014, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/24626990

Tracy A. Brennan, et.al., Mouse models of telomere dysfunction phenocopy skeletal changes found in human age-related osteoporosis., Disease models & mechanisms, 2014, 7

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased compact bone thickness_Terc<tm1Rdp>/Terc<tm1Rdp>,Wrn<tm1Lgu>/Wrn<tm1Lgu>
  http://metadb.riken.jp/0000135I129SvBALBcC57BL6SLJTerctm1RdpTerctm1RdpWrntm1LguWrntm1LguTerctm1RdpWrntm1Lgu
• increased osteoclast cell number_Wrn<tm1Lgu>/Wrn<tm1Lgu>
  http://metadb.riken.jp/0004984B6JCgWrntm1LguWrntm1LguWrntm1LguWrntm1Lgu
• osteoporosis_Terc<tm1Rdp>/Terc<tm1Rdp>,Wrn<tm1Lgu>/Wrn<tm1Lgu>
  http://metadb.riken.jp/0000066I129SvBALBcC57BL6SLJTerctm1RdpTerctm1RdpWrntm1LguWrntm1LguTerctm1RdpWrntm1Lgu
• decreased trabecular bone thickness_Terc<tm1Rdp>/Terc<tm1Rdp>,Wrn<tm1Lgu>/Wrn<tm1Lgu>
  http://metadb.riken.jp/0009346I129SvBALBcC57BL6SLJTerctm1RdpTerctm1RdpWrntm1LguWrntm1LguTerctm1RdpWrntm1Lgu
• decreased bone volume_Wrn<tm1Lgu>/Wrn<tm1Lgu>
  http://metadb.riken.jp/0010876B6JCgWrntm1LguWrntm1LguWrntm1LguWrntm1Lgu
• decreased bone volume_Terc<tm1Rdp>/Terc<tm1Rdp>,Wrn<tm1Lgu>/Wrn<tm1Lgu>
  http://metadb.riken.jp/0010876I129SvBALBcC57BL6SLJTerctm1RdpTerctm1RdpWrntm1LguWrntm1LguTerctm1RdpWrntm1Lgu
• abnormal compact bone morphology_Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0003797B6JCgTerctm1RdpTerctm1RdpTerctm1RdpTerctm1Rdp
• abnormal skeleton physiology_Terc<tm1Rdp>/Terc<tm1Rdp>,Wrn<tm1Lgu>/Wrn<tm1Lgu>
  http://metadb.riken.jp/0001533I129SvBALBcC57BL6SLJTerctm1RdpTerctm1RdpWrntm1LguWrntm1LguTerctm1RdpWrntm1Lgu
• abnormal bone trabecula morphology_Terc<tm1Rdp>/Terc<tm1Rdp>,Wrn<tm1Lgu>/Wrn<tm1Lgu>
  http://metadb.riken.jp/0010867I129SvBALBcC57BL6SLJTerctm1RdpTerctm1RdpWrntm1LguWrntm1LguTerctm1RdpWrntm1Lgu
• decreased bone trabecula number_Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0010869B6JCgTerctm1RdpTerctm1RdpTerctm1RdpTerctm1Rdp
• decreased compact bone area_Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0010968B6JCgTerctm1RdpTerctm1RdpTerctm1RdpTerctm1Rdp
• abnormal bone marrow morphology_Terc<tm1Rdp>/Terc<tm1Rdp>,Wrn<tm1Lgu>/Wrn<tm1Lgu>
  http://metadb.riken.jp/0002397I129SvBALBcC57BL6SLJTerctm1RdpTerctm1RdpWrntm1LguWrntm1LguTerctm1RdpWrntm1Lgu
• decreased bone volume_Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0010876B6JCgTerctm1RdpTerctm1RdpTerctm1RdpTerctm1Rdp
• abnormal adipose tissue distribution_Terc<tm1Rdp>/Terc<tm1Rdp>,Wrn<tm1Lgu>/Wrn<tm1Lgu>
  http://metadb.riken.jp/0000013I129SvBALBcC57BL6SLJTerctm1RdpTerctm1RdpWrntm1LguWrntm1LguTerctm1RdpWrntm1Lgu
• abnormal compact bone morphology_Terc<tm1Rdp>/Terc<tm1Rdp>,Wrn<tm1Lgu>/Wrn<tm1Lgu>
  http://metadb.riken.jp/0003797I129SvBALBcC57BL6SLJTerctm1RdpTerctm1RdpWrntm1LguWrntm1LguTerctm1RdpWrntm1Lgu
• abnormal bone ossification_Terc<tm1Rdp>/Terc<tm1Rdp>,Wrn<tm1Lgu>/Wrn<tm1Lgu>
  http://metadb.riken.jp/0008271I129SvBALBcC57BL6SLJTerctm1RdpTerctm1RdpWrntm1LguWrntm1LguTerctm1RdpWrntm1Lgu
• decreased compact bone thickness_Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0000135B6JCgTerctm1RdpTerctm1RdpTerctm1RdpTerctm1Rdp
• osteoporosis_Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0000066B6JCgTerctm1RdpTerctm1RdpTerctm1RdpTerctm1Rdp
• abnormal skeleton physiology_Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0001533B6JCgTerctm1RdpTerctm1RdpTerctm1RdpTerctm1Rdp
• abnormal osteoid morphology_Terc<tm1Rdp>/Terc<tm1Rdp>,Wrn<tm1Lgu>/Wrn<tm1Lgu>
  http://metadb.riken.jp/0010924I129SvBALBcC57BL6SLJTerctm1RdpTerctm1RdpWrntm1LguWrntm1LguTerctm1RdpWrntm1Lgu
• abnormal bone marrow morphology_Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0002397B6JCgTerctm1RdpTerctm1RdpTerctm1RdpTerctm1Rdp
• increased bone trabecular spacing_Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0013630B6JCgTerctm1RdpTerctm1RdpTerctm1RdpTerctm1Rdp
• increased bone trabecular spacing_Terc<tm1Rdp>/Terc<tm1Rdp>,Wrn<tm1Lgu>/Wrn<tm1Lgu>
  http://metadb.riken.jp/0013630I129SvBALBcC57BL6SLJTerctm1RdpTerctm1RdpWrntm1LguWrntm1LguTerctm1RdpWrntm1Lgu
• abnormal osteoid morphology_Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0010924B6JCgTerctm1RdpTerctm1RdpTerctm1RdpTerctm1Rdp
• decreased bone trabecula number_Terc<tm1Rdp>/Terc<tm1Rdp>,Wrn<tm1Lgu>/Wrn<tm1Lgu>
  http://metadb.riken.jp/0010869I129SvBALBcC57BL6SLJTerctm1RdpTerctm1RdpWrntm1LguWrntm1LguTerctm1RdpWrntm1Lgu
• decreased compact bone area_Terc<tm1Rdp>/Terc<tm1Rdp>,Wrn<tm1Lgu>/Wrn<tm1Lgu>
  http://metadb.riken.jp/0010968I129SvBALBcC57BL6SLJTerctm1RdpTerctm1RdpWrntm1LguWrntm1LguTerctm1RdpWrntm1Lgu
• abnormal bone ossification_Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0008271B6JCgTerctm1RdpTerctm1RdpTerctm1RdpTerctm1Rdp
• abnormal adipose tissue distribution_Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0000013B6JCgTerctm1RdpTerctm1RdpTerctm1RdpTerctm1Rdp
• decreased trabecular bone thickness_Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0009346B6JCgTerctm1RdpTerctm1RdpTerctm1RdpTerctm1Rdp