Scott. Smemo, et.al., Obesity-associated variants within FTO form long-range functional connections with IRX3., Nature, 2014, 507

http://rdf.ncbi.nlm.nih.gov/pubmed/24646999

Scott. Smemo, et.al., Obesity-associated variants within FTO form long-range functional connections with IRX3., Nature, 2014, 507

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(Irx3*)Hui>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5616234

class

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(Irx3*)Hui>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5616234

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased energy expenditure_Irx3<tm1Hui>/Irx3<tm1Hui>
  http://metadb.riken.jp/0004889I129S1Sv129X1SvJIrx3tm1HuiIrx3tm1HuiIrx3tm1Hui
• abnormal white adipose tissue physiology_Gt(ROSA)26Sor<tm1(Irx3*)Hui>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005670IC57BL6DBAGtROSA26Sortm1Irx3HuiGtROSA26SorTgIns2cre25Mgn0GtROSA26SorTgIns2cre25MgnGtROSA26Sortm1Irx3Hui
• increased energy expenditure_Gt(ROSA)26Sor<tm1(Irx3*)Hui>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0004889IC57BL6DBAGtROSA26Sortm1Irx3HuiGtROSA26SorTgIns2cre25Mgn0GtROSA26SorTgIns2cre25MgnGtROSA26Sortm1Irx3Hui
• decreased susceptibility to diet-induced obesity_Irx3<tm1Hui>/Irx3<tm1Hui>
  http://metadb.riken.jp/0005659I129S1Sv129X1SvJIrx3tm1HuiIrx3tm1HuiIrx3tm1Hui
• decreased body weight_Gt(ROSA)26Sor<tm1(Irx3*)Hui>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0001262IC57BL6DBAGtROSA26Sortm1Irx3HuiGtROSA26SorTgIns2cre25Mgn0GtROSA26SorTgIns2cre25MgnGtROSA26Sortm1Irx3Hui
• decreased fat cell size_Irx3<tm1Hui>/Irx3<tm1Hui>
  http://metadb.riken.jp/0009269I129S1Sv129X1SvJIrx3tm1HuiIrx3tm1HuiIrx3tm1Hui
• decreased susceptibility to hepatic steatosis_Irx3<tm1Hui>/Irx3<tm1Hui>
  http://metadb.riken.jp/0002310I129S1Sv129X1SvJIrx3tm1HuiIrx3tm1HuiIrx3tm1Hui
• increased insulin sensitivity_Irx3<tm1Hui>/Irx3<tm1Hui>
  http://metadb.riken.jp/0002891I129S1Sv129X1SvJIrx3tm1HuiIrx3tm1HuiIrx3tm1Hui
• decreased body weight_Irx3<tm1Hui>/Irx3<tm1Hui>
  http://metadb.riken.jp/0001262I129S1Sv129X1SvJIrx3tm1HuiIrx3tm1HuiIrx3tm1Hui
• improved glucose tolerance_Irx3<tm1Hui>/Irx3<tm1Hui>
  http://metadb.riken.jp/0005292I129S1Sv129X1SvJIrx3tm1HuiIrx3tm1HuiIrx3tm1Hui
• improved glucose tolerance_Gt(ROSA)26Sor<tm1(Irx3*)Hui>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005292IC57BL6DBAGtROSA26Sortm1Irx3HuiGtROSA26SorTgIns2cre25Mgn0GtROSA26SorTgIns2cre25MgnGtROSA26Sortm1Irx3Hui
• decreased fat cell size_Gt(ROSA)26Sor<tm1(Irx3*)Hui>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0009269IC57BL6DBAGtROSA26Sortm1Irx3HuiGtROSA26SorTgIns2cre25Mgn0GtROSA26SorTgIns2cre25MgnGtROSA26Sortm1Irx3Hui
• decreased percent body fat/body weight_Gt(ROSA)26Sor<tm1(Irx3*)Hui>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005459IC57BL6DBAGtROSA26Sortm1Irx3HuiGtROSA26SorTgIns2cre25Mgn0GtROSA26SorTgIns2cre25MgnGtROSA26Sortm1Irx3Hui
• abnormal white adipose tissue physiology_Irx3<tm1Hui>/Irx3<tm1Hui>
  http://metadb.riken.jp/0005670I129S1Sv129X1SvJIrx3tm1HuiIrx3tm1HuiIrx3tm1Hui
• decreased percent body fat/body weight_Irx3<tm1Hui>/Irx3<tm1Hui>
  http://metadb.riken.jp/0005459I129S1Sv129X1SvJIrx3tm1HuiIrx3tm1HuiIrx3tm1Hui