Adlen. Foudi, et.al., Distinct, strict requirements for Gfi-1b in adult bone marrow red cell and platelet generation., The Journal of experimental medicine, 2014, 211

http://rdf.ncbi.nlm.nih.gov/pubmed/24711581

Adlen. Foudi, et.al., Distinct, strict requirements for Gfi-1b in adult bone marrow red cell and platelet generation., The Journal of experimental medicine, 2014, 211

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gfi1b<tm1.1Haho>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5558052
• Col1a1<tm1(tetO-cre)Haho>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5558024

class

http://purl.org/net/cito/citesAsAuthority

• Gfi1b<tm1.1Haho>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5558052
• Col1a1<tm1(tetO-cre)Haho>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5558024

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• absent platelets_Gfi1b<tm1.1Haho>/Gfi1b<tm1.1Haho>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0003714I129S4SvJaeSorC57BL6Gfi1btm11HahoGfi1btm11HahoTgMx1cre1Cgn0Gfi1btm11HahoTgMx1cre1Cgn
• abnormal megakaryocyte progenitor cell morphology_Col1a1<tm1(tetO-cre)Haho>/?,Gfi1b<tm1.1Haho>/Gfi1b<tm1.1Haho>
  http://metadb.riken.jp/0002413I129S4SvJaeSorC57BL6Col1a1tm1tetOcreHahoGfi1btm11HahoGfi1btm11HahoCol1a1tm1tetOcreHahoGfi1btm11Haho
• thrombocytopenia_Col1a1<tm1(tetO-cre)Haho>/?,Gfi1b<tm1.1Haho>/Gfi1b<tm1.1Haho>
  http://metadb.riken.jp/0003179I129S4SvJaeSorC57BL6Col1a1tm1tetOcreHahoGfi1btm11HahoGfi1btm11HahoCol1a1tm1tetOcreHahoGfi1btm11Haho
• abnormal megakaryocyte progenitor cell morphology_Gfi1b<tm1.1Haho>/Gfi1b<tm1.1Haho>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002413I129S4SvJaeSorC57BL6Gfi1btm11HahoGfi1btm11HahoTgMx1cre1Cgn0Gfi1btm11HahoTgMx1cre1Cgn
• absent erythroid progenitor cell_Col1a1<tm1(tetO-cre)Haho>/?,Gfi1b<tm1.1Haho>/Gfi1b<tm1.1Haho>
  http://metadb.riken.jp/0000216I129S4SvJaeSorC57BL6Col1a1tm1tetOcreHahoGfi1btm11HahoGfi1btm11HahoCol1a1tm1tetOcreHahoGfi1btm11Haho
• decreased hemoglobin content_Col1a1<tm1(tetO-cre)Haho>/?,Gfi1b<tm1.1Haho>/Gfi1b<tm1.1Haho>
  http://metadb.riken.jp/0002874I129S4SvJaeSorC57BL6Col1a1tm1tetOcreHahoGfi1btm11HahoGfi1btm11HahoCol1a1tm1tetOcreHahoGfi1btm11Haho
• anemia_Col1a1<tm1(tetO-cre)Haho>/?,Gfi1b<tm1.1Haho>/Gfi1b<tm1.1Haho>
  http://metadb.riken.jp/0001577I129S4SvJaeSorC57BL6Col1a1tm1tetOcreHahoGfi1btm11HahoGfi1btm11HahoCol1a1tm1tetOcreHahoGfi1btm11Haho
• abnormal bone marrow cell morphology/development_Gfi1b<tm1.1Haho>/Gfi1b<tm1.1Haho>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002398I129S4SvJaeSorC57BL6Gfi1btm11HahoGfi1btm11HahoTgMx1cre1Cgn0Gfi1btm11HahoTgMx1cre1Cgn
• abnormal megakaryocyte differentiation_Gfi1b<tm1.1Haho>/Gfi1b<tm1.1Haho>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000229I129S4SvJaeSorC57BL6Gfi1btm11HahoGfi1btm11HahoTgMx1cre1Cgn0Gfi1btm11HahoTgMx1cre1Cgn
• abnormal megakaryocyte differentiation_Col1a1<tm1(tetO-cre)Haho>/?,Gfi1b<tm1.1Haho>/Gfi1b<tm1.1Haho>
  http://metadb.riken.jp/0000229I129S4SvJaeSorC57BL6Col1a1tm1tetOcreHahoGfi1btm11HahoGfi1btm11HahoCol1a1tm1tetOcreHahoGfi1btm11Haho
• postnatal lethality, complete penetrance_Col1a1<tm1(tetO-cre)Haho>/?,Gfi1b<tm1.1Haho>/Gfi1b<tm1.1Haho>
  http://metadb.riken.jp/0011085I129S4SvJaeSorC57BL6Col1a1tm1tetOcreHahoGfi1btm11HahoGfi1btm11HahoCol1a1tm1tetOcreHahoGfi1btm11Haho
• decreased hemoglobin content_Gfi1b<tm1.1Haho>/Gfi1b<tm1.1Haho>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002874I129S4SvJaeSorC57BL6Gfi1btm11HahoGfi1btm11HahoTgMx1cre1Cgn0Gfi1btm11HahoTgMx1cre1Cgn
• anemia_Gfi1b<tm1.1Haho>/Gfi1b<tm1.1Haho>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001577I129S4SvJaeSorC57BL6Gfi1btm11HahoGfi1btm11HahoTgMx1cre1Cgn0Gfi1btm11HahoTgMx1cre1Cgn
• absent platelets_Col1a1<tm1(tetO-cre)Haho>/?,Gfi1b<tm1.1Haho>/Gfi1b<tm1.1Haho>
  http://metadb.riken.jp/0003714I129S4SvJaeSorC57BL6Col1a1tm1tetOcreHahoGfi1btm11HahoGfi1btm11HahoCol1a1tm1tetOcreHahoGfi1btm11Haho
• thrombocytopenia_Gfi1b<tm1.1Haho>/Gfi1b<tm1.1Haho>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0003179I129S4SvJaeSorC57BL6Gfi1btm11HahoGfi1btm11HahoTgMx1cre1Cgn0Gfi1btm11HahoTgMx1cre1Cgn
• absent erythroid progenitor cell_Gfi1b<tm1.1Haho>/Gfi1b<tm1.1Haho>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000216I129S4SvJaeSorC57BL6Gfi1btm11HahoGfi1btm11HahoTgMx1cre1Cgn0Gfi1btm11HahoTgMx1cre1Cgn
• postnatal lethality, complete penetrance_Gfi1b<tm1.1Haho>/Gfi1b<tm1.1Haho>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0011085I129S4SvJaeSorC57BL6Gfi1btm11HahoGfi1btm11HahoTgMx1cre1Cgn0Gfi1btm11HahoTgMx1cre1Cgn