Jinsoo. Seo, et.al., Activity-dependent p25 generation regulates synaptic plasticity and Aβ-induced cognitive impairment., Cell, 2014, 157

http://rdf.ncbi.nlm.nih.gov/pubmed/24725413

Jinsoo. Seo, et.al., Activity-dependent p25 generation regulates synaptic plasticity and Aβ-induced cognitive impairment., Cell, 2014, 157

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cdk5r1<tm2.1Lht>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5560495

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• impaired contextual conditioning behavior_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/?
  http://metadb.riken.jp/0009454IC57BL6SJLTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas
• abnormal excitatory postsynaptic potential_Cdk5r1<tm2.1Lht>/Cdk5r1<tm2.1Lht>
  http://metadb.riken.jp/0002912B6129Cdk5r1tm21LhtCdk5r1tm21LhtCdk5r1tm21LhtCdk5r1tm21Lht
• abnormal microglial cell activation_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/?
  http://metadb.riken.jp/0010762IC57BL6SJLTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas
• slow extinction of fear memory_Cdk5r1<tm2.1Lht>/Cdk5r1<tm2.1Lht>
  http://metadb.riken.jp/0012318B6129Cdk5r1tm21LhtCdk5r1tm21LhtCdk5r1tm21LhtCdk5r1tm21Lht
• abnormal long term depression_Cdk5r1<tm2.1Lht>/Cdk5r1<tm2.1Lht>
  http://metadb.riken.jp/0001898B6129Cdk5r1tm21LhtCdk5r1tm21LhtCdk5r1tm21LhtCdk5r1tm21Lht
• abnormal response to novel object_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/?
  http://metadb.riken.jp/0003461IC57BL6SJLTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas
• impaired cued conditioning behavior_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/?
  http://metadb.riken.jp/0009456IC57BL6SJLTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas
• abnormal long term depression_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/?
  http://metadb.riken.jp/0001898IC57BL6SJLTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas
• amyloid beta deposits_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/?
  http://metadb.riken.jp/0003329IC57BL6SJLTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas
• amyloid beta deposits_Cdk5r1<tm2.1Lht>/?,Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/?
  http://metadb.riken.jp/0003329I129S4SvJaeSorC57BL6SJLCdk5r1tm21LhtTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasCdk5r1tm21Lht
• abnormal astrocyte physiology_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/?
  http://metadb.riken.jp/0008916IC57BL6SJLTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas

class

http://purl.org/net/cito/citesAsAuthority

• Cdk5r1<tm2.1Lht>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5560495