Karolina. Kolodziejczyk, et.al., Striatal synaptic dysfunction and hippocampal plasticity deficits in the Hu97/18 mouse model of Huntington disease., PloS one, 2014, 9

http://rdf.ncbi.nlm.nih.gov/pubmed/24728353

Karolina. Kolodziejczyk, et.al., Striatal synaptic dysfunction and hippocampal plasticity deficits in the Hu97/18 mouse model of Huntington disease., PloS one, 2014, 9

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal CNS synaptic transmission_Htt<tm1Hay>/Htt<tm1Hay>,Tg(HTT*97Q)IXwy/0,Tg(YAC18)18Hay/Tg(YAC18)18Hay
  http://metadb.riken.jp/0002206FVBCgHtttm1HayTgHTT97QIXwyTgYAC1818HayHtttm1HayHtttm1HayTgHTT97QIXwy0TgYAC1818HayTgYAC1818HayTgYAC1818HayTgHTT97QIXwyHtttm1Hay
• decreased excitatory postsynaptic current amplitude_Htt<tm1Hay>/Htt<tm1Hay>,Tg(HTT*97Q)IXwy/0,Tg(YAC18)18Hay/Tg(YAC18)18Hay
  http://metadb.riken.jp/0011270FVBCgHtttm1HayTgHTT97QIXwyTgYAC1818HayHtttm1HayHtttm1HayTgHTT97QIXwy0TgYAC1818HayTgYAC1818HayTgYAC1818HayTgHTT97QIXwyHtttm1Hay
• reduced long term potentiation_Htt<tm1Hay>/Htt<tm1Hay>,Tg(HTT*97Q)IXwy/0,Tg(YAC18)18Hay/Tg(YAC18)18Hay
  http://metadb.riken.jp/0001473FVBCgHtttm1HayTgHTT97QIXwyTgYAC1818HayHtttm1HayHtttm1HayTgHTT97QIXwy0TgYAC1818HayTgYAC1818HayTgYAC1818HayTgHTT97QIXwyHtttm1Hay
• abnormal action potential_Htt<tm1Hay>/Htt<tm1Hay>,Tg(HTT*97Q)IXwy/0,Tg(YAC18)18Hay/Tg(YAC18)18Hay
  http://metadb.riken.jp/0005402FVBCgHtttm1HayTgHTT97QIXwyTgYAC1818HayHtttm1HayHtttm1HayTgHTT97QIXwy0TgYAC1818HayTgYAC1818HayTgYAC1818HayTgHTT97QIXwyHtttm1Hay
• decreased paired-pulse facilitation_Htt<tm1Hay>/Htt<tm1Hay>,Tg(HTT*97Q)IXwy/0,Tg(YAC18)18Hay/Tg(YAC18)18Hay
  http://metadb.riken.jp/0002920FVBCgHtttm1HayTgHTT97QIXwyTgYAC1818HayHtttm1HayHtttm1HayTgHTT97QIXwy0TgYAC1818HayTgYAC1818HayTgYAC1818HayTgHTT97QIXwyHtttm1Hay
• abnormal excitatory postsynaptic currents_Htt<tm1Hay>/Htt<tm1Hay>,Tg(HTT*97Q)IXwy/0,Tg(YAC18)18Hay/Tg(YAC18)18Hay
  http://metadb.riken.jp/0002910FVBCgHtttm1HayTgHTT97QIXwyTgYAC1818HayHtttm1HayHtttm1HayTgHTT97QIXwy0TgYAC1818HayTgYAC1818HayTgYAC1818HayTgHTT97QIXwyHtttm1Hay
• impaired synaptic plasticity_Htt<tm1Hay>/Htt<tm1Hay>,Tg(HTT*97Q)IXwy/0,Tg(YAC18)18Hay/Tg(YAC18)18Hay
  http://metadb.riken.jp/0001900FVBCgHtttm1HayTgHTT97QIXwyTgYAC1818HayHtttm1HayHtttm1HayTgHTT97QIXwy0TgYAC1818HayTgYAC1818HayTgYAC1818HayTgHTT97QIXwyHtttm1Hay