Isabella. Saggio, et.al., Constitutive expression of Gsα(R201C) in mice produces a heritable, direct replica of human fibrous dysplasia bone pathology and demonstrates its natural history., Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2014, 29

http://rdf.ncbi.nlm.nih.gov/pubmed/24764158

http://rdf.ncbi.nlm.nih.gov/pubmed/24764158

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(PGK1-Gnas*R201C)60Pabi
  http://metadb.riken.jp/db/mgi_rdf/MGI:5883014
• Tg(EEF1A1-Gnas*R201C)184Pabi
  http://metadb.riken.jp/db/mgi_rdf/MGI:5883023

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• fragile skeleton_Tg(EEF1A1-Gnas*R201C)184Pabi/0
  http://metadb.riken.jp/0000061EI129S6SvEvTacC57BL6orI129S6SvEvTacFVBNTgEEF1A1GnasR201C184Pabi0TgEEF1A1GnasR201C184Pabi
• fragile skeleton_Tg(PGK1-Gnas*R201C)60Pabi/0
  http://metadb.riken.jp/0000061EI129S6SvEvTacC57BL6orI129S6SvEvTacFVBNTgPGK1GnasR201C60Pabi0TgPGK1GnasR201C60Pabi
• abnormal bone marrow cavity morphology_Tg(EEF1A1-Gnas*R201C)184Pabi/0
  http://metadb.riken.jp/0000065EI129S6SvEvTacC57BL6orI129S6SvEvTacFVBNTgEEF1A1GnasR201C184Pabi0TgEEF1A1GnasR201C184Pabi
• abnormal bone mineralization_Tg(EEF1A1-Gnas*R201C)184Pabi/0
  http://metadb.riken.jp/0002896EI129S6SvEvTacC57BL6orI129S6SvEvTacFVBNTgEEF1A1GnasR201C184Pabi0TgEEF1A1GnasR201C184Pabi
• abnormal bone remodeling_Tg(EEF1A1-Gnas*R201C)184Pabi/0
  http://metadb.riken.jp/0002998EI129S6SvEvTacC57BL6orI129S6SvEvTacFVBNTgEEF1A1GnasR201C184Pabi0TgEEF1A1GnasR201C184Pabi
• abnormal compact bone morphology_Tg(EEF1A1-Gnas*R201C)184Pabi/0
  http://metadb.riken.jp/0003797EI129S6SvEvTacC57BL6orI129S6SvEvTacFVBNTgEEF1A1GnasR201C184Pabi0TgEEF1A1GnasR201C184Pabi
他8件を見る
• increased bone resorption_Tg(EEF1A1-Gnas*R201C)184Pabi/0
  http://metadb.riken.jp/0004992EI129S6SvEvTacC57BL6orI129S6SvEvTacFVBNTgEEF1A1GnasR201C184Pabi0TgEEF1A1GnasR201C184Pabi
• osteosclerosis_Tg(EEF1A1-Gnas*R201C)184Pabi/0
  http://metadb.riken.jp/0005422EI129S6SvEvTacC57BL6orI129S6SvEvTacFVBNTgEEF1A1GnasR201C184Pabi0TgEEF1A1GnasR201C184Pabi
• abnormal skeleton morphology_Tg(EEF1A1-Gnas*R201C)184Pabi/0
  http://metadb.riken.jp/0005508EI129S6SvEvTacC57BL6orI129S6SvEvTacFVBNTgEEF1A1GnasR201C184Pabi0TgEEF1A1GnasR201C184Pabi
• abnormal skeleton morphology_Tg(PGK1-Gnas*R201C)60Pabi/0
  http://metadb.riken.jp/0005508EI129S6SvEvTacC57BL6orI129S6SvEvTacFVBNTgPGK1GnasR201C60Pabi0TgPGK1GnasR201C60Pabi
• exostosis_Tg(EEF1A1-Gnas*R201C)184Pabi/0
  http://metadb.riken.jp/0009877EI129S6SvEvTacC57BL6orI129S6SvEvTacFVBNTgEEF1A1GnasR201C184Pabi0TgEEF1A1GnasR201C184Pabi
• abnormal bone trabecula morphology_Tg(EEF1A1-Gnas*R201C)184Pabi/0
  http://metadb.riken.jp/0010867EI129S6SvEvTacC57BL6orI129S6SvEvTacFVBNTgEEF1A1GnasR201C184Pabi0TgEEF1A1GnasR201C184Pabi
• increased internal diameter of femur_Tg(EEF1A1-Gnas*R201C)184Pabi/0
  http://metadb.riken.jp/0013620EI129S6SvEvTacC57BL6orI129S6SvEvTacFVBNTgEEF1A1GnasR201C184Pabi0TgEEF1A1GnasR201C184Pabi
• increased bone ossification_Tg(EEF1A1-Gnas*R201C)184Pabi/0
  http://metadb.riken.jp/0020039EI129S6SvEvTacC57BL6orI129S6SvEvTacFVBNTgEEF1A1GnasR201C184Pabi0TgEEF1A1GnasR201C184Pabi

class

http://purl.org/net/cito/citesAsAuthority

• Tg(PGK1-Gnas*R201C)60Pabi
  http://metadb.riken.jp/db/mgi_rdf/MGI:5883014
• Tg(EEF1A1-Gnas*R201C)184Pabi
  http://metadb.riken.jp/db/mgi_rdf/MGI:5883023