Michael D. Kritzer, et.al., The scaffold protein muscle A-kinase anchoring protein β orchestrates cardiac myocyte hypertrophic signaling required for the development of heart failure., Circulation. Heart failure, 2014, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/24812305

Michael D. Kritzer, et.al., The scaffold protein muscle A-kinase anchoring protein β orchestrates cardiac myocyte hypertrophic signaling required for the development of heart failure., Circulation. Heart failure, 2014, 7

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Akap6<tm1.1Mskf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5588705
• Akap6<tm1.2Mskf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5603562

class

http://purl.org/net/cito/citesAsAuthority

• Akap6<tm1.1Mskf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5588705
• Akap6<tm1.2Mskf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5603562

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• heart left ventricle hypertrophy_Akap6<tm1.1Mskf>/Akap6<tm1.1Mskf>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0002625IC57BL6FVBNSJLAkap6tm11MskfAkap6tm11MskfA1cfTgMyh6creEsr11Jmk0Akap6tm11MskfA1cfTgMyh6creEsr11Jmk
• increased left ventricle weight_Akap6<tm1.1Mskf>/Akap6<tm1.1Mskf>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0003915IC57BL6FVBNSJLAkap6tm11MskfAkap6tm11MskfA1cfTgMyh6creEsr11Jmk0Akap6tm11MskfA1cfTgMyh6creEsr11Jmk
• cardiac interstitial fibrosis_Akap6<tm1.1Mskf>/Akap6<tm1.1Mskf>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0005608IC57BL6FVBNSJLAkap6tm11MskfAkap6tm11MskfA1cfTgMyh6creEsr11Jmk0Akap6tm11MskfA1cfTgMyh6creEsr11Jmk
• increased cardiomyocyte apoptosis_Akap6<tm1.1Mskf>/Akap6<tm1.1Mskf>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0003222IC57BL6FVBNSJLAkap6tm11MskfAkap6tm11MskfA1cfTgMyh6creEsr11Jmk0Akap6tm11MskfA1cfTgMyh6creEsr11Jmk
• enlarged myocardial fiber_Akap6<tm1.1Mskf>/Akap6<tm1.1Mskf>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0004564IC57BL6FVBNSJLAkap6tm11MskfAkap6tm11MskfA1cfTgMyh6creEsr11Jmk0Akap6tm11MskfA1cfTgMyh6creEsr11Jmk
• decreased heart rate_Akap6<tm1.1Mskf>/Akap6<tm1.1Mskf>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0005333IC57BL6FVBNSJLAkap6tm11MskfAkap6tm11MskfA1cfTgMyh6creEsr11Jmk0Akap6tm11MskfA1cfTgMyh6creEsr11Jmk
• increased heart left atrium weight_Akap6<tm1.1Mskf>/Akap6<tm1.1Mskf>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0011915IC57BL6FVBNSJLAkap6tm11MskfAkap6tm11MskfA1cfTgMyh6creEsr11Jmk0Akap6tm11MskfA1cfTgMyh6creEsr11Jmk
• abnormal heart ventricles weight_Akap6<tm1.1Mskf>/Akap6<tm1.1Mskf>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0012688IC57BL6FVBNSJLAkap6tm11MskfAkap6tm11MskfA1cfTgMyh6creEsr11Jmk0Akap6tm11MskfA1cfTgMyh6creEsr11Jmk
• no abnormal phenotype detected_Akap6<tm1.1Mskf>/Akap6<tm1.1Mskf>,Nkx2-5<tm1(cre)Rjs>/0
  http://metadb.riken.jp/0002169I129S7SvEvBrdC57BL6SJLAkap6tm11MskfAkap6tm11MskfNkx25tm1creRjs0Akap6tm11MskfNkx25tm1creRjs
• neonatal lethality_Akap6<tm1.2Mskf>/Akap6<tm1.2Mskf>
  http://metadb.riken.jp/0002058IBALBcJC57BL6SJLAkap6tm12MskfAkap6tm12MskfAkap6tm12Mskf
• thick ventricular wall_Akap6<tm1.1Mskf>/Akap6<tm1.1Mskf>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0002953IC57BL6FVBNSJLAkap6tm11MskfAkap6tm11MskfA1cfTgMyh6creEsr11Jmk0Akap6tm11MskfA1cfTgMyh6creEsr11Jmk