Elena. Amendola, et.al., Mapping pathological phenotypes in a mouse model of CDKL5 disorder., PloS one, 2014, 9

http://rdf.ncbi.nlm.nih.gov/pubmed/24838000

Elena. Amendola, et.al., Mapping pathological phenotypes in a mouse model of CDKL5 disorder., PloS one, 2014, 9

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cdkl5<tm1Cogr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5573225
• Cdkl5<tm1.2Cogr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5573238
• Cdkl5<tm1.3Cogr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5573245
• Cdkl5<tm1.1Cogr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5573232

class

http://purl.org/net/cito/citesAsAuthority

• Cdkl5<tm1Cogr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5573225
• Cdkl5<tm1.2Cogr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5573238
• Cdkl5<tm1.3Cogr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5573245
• Cdkl5<tm1.1Cogr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5573232

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal visual evoked potential_Cdkl5<tm1.2Cogr>/Y
  http://metadb.riken.jp/0010748I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6JCdkl5tm12CogrYCdkl5tm12Cogr
• seizures_Cdkl5<tm1.2Cogr>/Y
  http://metadb.riken.jp/0002064I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6JCdkl5tm12CogrYCdkl5tm12Cogr
• thin cerebral cortex_Cdkl5<tm1.2Cogr>/Y,Tg(Thy1-YFP)#Jrs/0
  http://metadb.riken.jp/0006254I129P2OlaHsd129SSvC57BL6JCBACdkl5tm12CogrYTgThy1YFPJrs0TgThy1YFPJrsCdkl5tm12Cogr
• thin hippocampus stratum oriens_Cdkl5<tm1.2Cogr>/Cdkl5<tm1.2Cogr>,Tg(Thy1-YFP)#Jrs/0
  http://metadb.riken.jp/0012446I129P2OlaHsd129SSvC57BL6JCBACdkl5tm12CogrCdkl5tm12CogrTgThy1YFPJrs0TgThy1YFPJrsCdkl5tm12Cogr
• abnormal seizure response to inducing agent_Cdkl5<tm1.2Cogr>/Cdkl5<tm1.2Cogr>
  http://metadb.riken.jp/0009357I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6JCdkl5tm12CogrCdkl5tm12CogrCdkl5tm12Cogr
• thin hippocampus molecular cell layer_Cdkl5<tm1.2Cogr>/Cdkl5<tm1.2Cogr>,Tg(Thy1-YFP)#Jrs/0
  http://metadb.riken.jp/0012444I129P2OlaHsd129SSvC57BL6JCBACdkl5tm12CogrCdkl5tm12CogrTgThy1YFPJrs0TgThy1YFPJrsCdkl5tm12Cogr
• hypoactivity_Cdkl5<tm1.2Cogr>/Cdkl5<tm1.2Cogr>
  http://metadb.riken.jp/0001402I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6JCdkl5tm12CogrCdkl5tm12CogrCdkl5tm12Cogr
• abnormal behavior_Cdkl5<tm1.3Cogr>/?
  http://metadb.riken.jp/0004924I129P2OlaHsd129S1SvC57BL6JCdkl5tm13CogrCdkl5tm13Cogr
• hypoactivity_Cdkl5<tm1.2Cogr>/Cdkl5<+>
  http://metadb.riken.jp/0001402I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6JCdkl5tm12CogrCdkl5Cdkl5tm12CogrCdkl5
• abnormal seizure response to inducing agent_Cdkl5<tm1.2Cogr>/Y
  http://metadb.riken.jp/0009357I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6JCdkl5tm12CogrYCdkl5tm12Cogr
• abnormal dendrite morphology_Cdkl5<tm1.2Cogr>/Cdkl5<tm1.2Cogr>,Tg(Thy1-YFP)#Jrs/0
  http://metadb.riken.jp/0008143I129P2OlaHsd129SSvC57BL6JCBACdkl5tm12CogrCdkl5tm12CogrTgThy1YFPJrs0TgThy1YFPJrsCdkl5tm12Cogr
• seizures_Cdkl5<tm1.2Cogr>/Cdkl5<tm1.2Cogr>
  http://metadb.riken.jp/0002064I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6JCdkl5tm12CogrCdkl5tm12CogrCdkl5tm12Cogr
• abnormal dendrite morphology_Cdkl5<tm1.2Cogr>/Y,Tg(Thy1-YFP)#Jrs/0
  http://metadb.riken.jp/0008143I129P2OlaHsd129SSvC57BL6JCBACdkl5tm12CogrYTgThy1YFPJrs0TgThy1YFPJrsCdkl5tm12Cogr
• abnormal visual evoked potential_Cdkl5<tm1.2Cogr>/Cdkl5<+>
  http://metadb.riken.jp/0010748I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6JCdkl5tm12CogrCdkl5Cdkl5tm12CogrCdkl5
• thin cerebral cortex_Cdkl5<tm1.2Cogr>/Cdkl5<+>,Tg(Thy1-YFP)#Jrs/0
  http://metadb.riken.jp/0006254I129P2OlaHsd129SSvC57BL6JCBACdkl5tm12CogrCdkl5TgThy1YFPJrs0Cdkl5TgThy1YFPJrsCdkl5tm12Cogr
• abnormal visual evoked potential_Cdkl5<tm1.2Cogr>/Cdkl5<tm1.2Cogr>
  http://metadb.riken.jp/0010748I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6JCdkl5tm12CogrCdkl5tm12CogrCdkl5tm12Cogr
• hypoactivity_Cdkl5<tm1.1Cogr>/?,Tg(dlx6a-cre)1Mekk/0
  http://metadb.riken.jp/0001402I129P2OlaHsd129S4SvJaeSorC57BL6JCD1Cdkl5tm11CogrTgdlx6acre1Mekk0Cdkl5tm11CogrTgdlx6acre1Mekk
• thin cerebral cortex_Cdkl5<tm1.2Cogr>/Cdkl5<tm1.2Cogr>,Tg(Thy1-YFP)#Jrs/0
  http://metadb.riken.jp/0006254I129P2OlaHsd129SSvC57BL6JCBACdkl5tm12CogrCdkl5tm12CogrTgThy1YFPJrs0TgThy1YFPJrsCdkl5tm12Cogr
• limb grasping_Cdkl5<tm1.2Cogr>/Cdkl5<+>
  http://metadb.riken.jp/0001513I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6JCdkl5tm12CogrCdkl5Cdkl5tm12CogrCdkl5
• abnormal dendrite morphology_Cdkl5<tm1.2Cogr>/Cdkl5<+>,Tg(Thy1-YFP)#Jrs/0
  http://metadb.riken.jp/0008143I129P2OlaHsd129SSvC57BL6JCBACdkl5tm12CogrCdkl5TgThy1YFPJrs0Cdkl5TgThy1YFPJrsCdkl5tm12Cogr
• limb grasping_Cdkl5<tm1.1Cogr>/Cdkl5<+>,Tg(Emx1-cre)#Ito/0
  http://metadb.riken.jp/0001513I129P2OlaHsd129S4SvJaeSorC57BL6C57BL6JCdkl5tm11CogrCdkl5TgEmx1creIto0Cdkl5tm11CogrCdkl5TgEmx1creIto
• hypoactivity_Cdkl5<tm1.2Cogr>/Y
  http://metadb.riken.jp/0001402I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6JCdkl5tm12CogrYCdkl5tm12Cogr
• limb grasping_Cdkl5<tm1.1Cogr>/Y,Tg(Emx1-cre)#Ito/0
  http://metadb.riken.jp/0001513I129P2OlaHsd129S4SvJaeSorC57BL6C57BL6JCdkl5tm11CogrYTgEmx1creIto0Cdkl5tm11CogrTgEmx1creIto
• thin hippocampus molecular cell layer_Cdkl5<tm1.2Cogr>/Y,Tg(Thy1-YFP)#Jrs/0
  http://metadb.riken.jp/0012444I129P2OlaHsd129SSvC57BL6JCBACdkl5tm12CogrYTgThy1YFPJrs0TgThy1YFPJrsCdkl5tm12Cogr
• limb grasping_Cdkl5<tm1.2Cogr>/Cdkl5<tm1.2Cogr>
  http://metadb.riken.jp/0001513I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6JCdkl5tm12CogrCdkl5tm12CogrCdkl5tm12Cogr
• abnormal hippocampus layer morphology_Cdkl5<tm1.2Cogr>/Cdkl5<tm1.2Cogr>,Tg(Thy1-YFP)#Jrs/0
  http://metadb.riken.jp/0000813I129P2OlaHsd129SSvC57BL6JCBACdkl5tm12CogrCdkl5tm12CogrTgThy1YFPJrs0TgThy1YFPJrsCdkl5tm12Cogr
• thin hippocampus stratum oriens_Cdkl5<tm1.2Cogr>/Y,Tg(Thy1-YFP)#Jrs/0
  http://metadb.riken.jp/0012446I129P2OlaHsd129SSvC57BL6JCBACdkl5tm12CogrYTgThy1YFPJrs0TgThy1YFPJrsCdkl5tm12Cogr
• abnormal hippocampus layer morphology_Cdkl5<tm1.2Cogr>/Y,Tg(Thy1-YFP)#Jrs/0
  http://metadb.riken.jp/0000813I129P2OlaHsd129SSvC57BL6JCBACdkl5tm12CogrYTgThy1YFPJrs0TgThy1YFPJrsCdkl5tm12Cogr
• limb grasping_Cdkl5<tm1.2Cogr>/Y
  http://metadb.riken.jp/0001513I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6JCdkl5tm12CogrYCdkl5tm12Cogr