Baiyin. Yuan, et.al., A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice., The American journal of pathology, 2014, 184

http://rdf.ncbi.nlm.nih.gov/pubmed/24840128

Baiyin. Yuan, et.al., A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice., The American journal of pathology, 2014, 184

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Wdr1<tm1.1Zzy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5636587

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased heart rate_Wdr1<tm1.1Zzy>/Wdr1<tm1.1Zzy>,Tg(Myhc-cre)1Xya/0
  http://metadb.riken.jp/0005333I129S6SvEvTacC57BL6JWdr1tm11ZzyWdr1tm11ZzyTgMyhccre1Xya0TgMyhccre1XyaWdr1tm11Zzy
• increased heart weight_Wdr1<tm1.1Zzy>/Wdr1<tm1.1Zzy>,Tg(Myhc-cre)1Xya/0
  http://metadb.riken.jp/0002833I129S6SvEvTacC57BL6JWdr1tm11ZzyWdr1tm11ZzyTgMyhccre1Xya0TgMyhccre1XyaWdr1tm11Zzy
• premature death_Wdr1<tm1.1Zzy>/Wdr1<tm1.1Zzy>,Tg(Myhc-cre)1Xya/0
  http://metadb.riken.jp/0002083I129S6SvEvTacC57BL6JWdr1tm11ZzyWdr1tm11ZzyTgMyhccre1Xya0TgMyhccre1XyaWdr1tm11Zzy
• abnormal myocardial fiber morphology_Wdr1<tm1.1Zzy>/Wdr1<tm1.1Zzy>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0000278I129S6SvEvTacC57BL6JWdr1tm11ZzyWdr1tm11ZzyA1cfTgMyh6creEsr11Jmk0Wdr1tm11ZzyA1cfTgMyh6creEsr11Jmk
• cardiac hypertrophy_Wdr1<tm1.1Zzy>/Wdr1<tm1.1Zzy>,Tg(Myhc-cre)1Xya/0
  http://metadb.riken.jp/0001625I129S6SvEvTacC57BL6JWdr1tm11ZzyWdr1tm11ZzyTgMyhccre1Xya0TgMyhccre1XyaWdr1tm11Zzy
• premature death_Wdr1<tm1.1Zzy>/Wdr1<tm1.1Zzy>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0002083I129S6SvEvTacC57BL6JWdr1tm11ZzyWdr1tm11ZzyA1cfTgMyh6creEsr11Jmk0Wdr1tm11ZzyA1cfTgMyh6creEsr11Jmk
• prolonged P wave_Wdr1<tm1.1Zzy>/Wdr1<tm1.1Zzy>,Tg(Myhc-cre)1Xya/0
  http://metadb.riken.jp/0004071I129S6SvEvTacC57BL6JWdr1tm11ZzyWdr1tm11ZzyTgMyhccre1Xya0TgMyhccre1XyaWdr1tm11Zzy
• abnormal interventricular septum morphology_Wdr1<tm1.1Zzy>/Wdr1<tm1.1Zzy>,Tg(Myhc-cre)1Xya/0
  http://metadb.riken.jp/0000281I129S6SvEvTacC57BL6JWdr1tm11ZzyWdr1tm11ZzyTgMyhccre1Xya0TgMyhccre1XyaWdr1tm11Zzy
• cardiac hypertrophy_Wdr1<tm1.1Zzy>/Wdr1<tm1.1Zzy>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0001625I129S6SvEvTacC57BL6JWdr1tm11ZzyWdr1tm11ZzyA1cfTgMyh6creEsr11Jmk0Wdr1tm11ZzyA1cfTgMyh6creEsr11Jmk
• no abnormal phenotype detected_Wdr1<tm1.1Zzy>/Wdr1<+>,Tg(Myhc-cre)1Xya/0
  http://metadb.riken.jp/0002169I129S6SvEvTacC57BL6JWdr1tm11ZzyWdr1TgMyhccre1Xya0Wdr1tm11ZzyWdr1TgMyhccre1Xya
• enlarged myocardial fiber_Wdr1<tm1.1Zzy>/Wdr1<tm1.1Zzy>,Tg(Myhc-cre)1Xya/0
  http://metadb.riken.jp/0004564I129S6SvEvTacC57BL6JWdr1tm11ZzyWdr1tm11ZzyTgMyhccre1Xya0TgMyhccre1XyaWdr1tm11Zzy
• abnormal T wave_Wdr1<tm1.1Zzy>/Wdr1<tm1.1Zzy>,Tg(Myhc-cre)1Xya/0
  http://metadb.riken.jp/0010505I129S6SvEvTacC57BL6JWdr1tm11ZzyWdr1tm11ZzyTgMyhccre1Xya0TgMyhccre1XyaWdr1tm11Zzy
• abnormal myocardial fiber morphology_Wdr1<tm1.1Zzy>/Wdr1<tm1.1Zzy>,Tg(Myhc-cre)1Xya/0
  http://metadb.riken.jp/0000278I129S6SvEvTacC57BL6JWdr1tm11ZzyWdr1tm11ZzyTgMyhccre1Xya0TgMyhccre1XyaWdr1tm11Zzy
• abnormal heart electrocardiography waveform feature_Wdr1<tm1.1Zzy>/Wdr1<tm1.1Zzy>,Tg(Myhc-cre)1Xya/0
  http://metadb.riken.jp/0010508I129S6SvEvTacC57BL6JWdr1tm11ZzyWdr1tm11ZzyTgMyhccre1Xya0TgMyhccre1XyaWdr1tm11Zzy
• prolonged QT interval_Wdr1<tm1.1Zzy>/Wdr1<tm1.1Zzy>,Tg(Myhc-cre)1Xya/0
  http://metadb.riken.jp/0003233I129S6SvEvTacC57BL6JWdr1tm11ZzyWdr1tm11ZzyTgMyhccre1Xya0TgMyhccre1XyaWdr1tm11Zzy
• enlarged myocardial fiber_Wdr1<tm1.1Zzy>/Wdr1<tm1.1Zzy>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0004564I129S6SvEvTacC57BL6JWdr1tm11ZzyWdr1tm11ZzyA1cfTgMyh6creEsr11Jmk0Wdr1tm11ZzyA1cfTgMyh6creEsr11Jmk
• prolonged ST segment_Wdr1<tm1.1Zzy>/Wdr1<tm1.1Zzy>,Tg(Myhc-cre)1Xya/0
  http://metadb.riken.jp/0010570I129S6SvEvTacC57BL6JWdr1tm11ZzyWdr1tm11ZzyTgMyhccre1Xya0TgMyhccre1XyaWdr1tm11Zzy
• enlarged heart_Wdr1<tm1.1Zzy>/Wdr1<tm1.1Zzy>,Tg(Myhc-cre)1Xya/0
  http://metadb.riken.jp/0000274I129S6SvEvTacC57BL6JWdr1tm11ZzyWdr1tm11ZzyTgMyhccre1Xya0TgMyhccre1XyaWdr1tm11Zzy
• decreased ventricle muscle contractility_Wdr1<tm1.1Zzy>/Wdr1<tm1.1Zzy>,Tg(Myhc-cre)1Xya/0
  http://metadb.riken.jp/0005598I129S6SvEvTacC57BL6JWdr1tm11ZzyWdr1tm11ZzyTgMyhccre1Xya0TgMyhccre1XyaWdr1tm11Zzy
• increased heart weight_Wdr1<tm1.1Zzy>/Wdr1<tm1.1Zzy>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0002833I129S6SvEvTacC57BL6JWdr1tm11ZzyWdr1tm11ZzyA1cfTgMyh6creEsr11Jmk0Wdr1tm11ZzyA1cfTgMyh6creEsr11Jmk
• abnormal myocardium layer morphology_Wdr1<tm1.1Zzy>/Wdr1<tm1.1Zzy>,Tg(Myhc-cre)1Xya/0
  http://metadb.riken.jp/0005329I129S6SvEvTacC57BL6JWdr1tm11ZzyWdr1tm11ZzyTgMyhccre1Xya0TgMyhccre1XyaWdr1tm11Zzy
• postnatal lethality, incomplete penetrance_Wdr1<tm1.1Zzy>/Wdr1<tm1.1Zzy>,Tg(Myhc-cre)1Xya/0
  http://metadb.riken.jp/0011086I129S6SvEvTacC57BL6JWdr1tm11ZzyWdr1tm11ZzyTgMyhccre1Xya0TgMyhccre1XyaWdr1tm11Zzy
• abnormal heart left ventricle morphology_Wdr1<tm1.1Zzy>/Wdr1<tm1.1Zzy>,Tg(Myhc-cre)1Xya/0
  http://metadb.riken.jp/0003921I129S6SvEvTacC57BL6JWdr1tm11ZzyWdr1tm11ZzyTgMyhccre1Xya0TgMyhccre1XyaWdr1tm11Zzy

class

http://purl.org/net/cito/citesAsAuthority

• Wdr1<tm1.1Zzy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5636587