Jian-Fu. Chen, et.al., Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size., Nature communications, 2014, 5

http://rdf.ncbi.nlm.nih.gov/pubmed/24875059

Jian-Fu. Chen, et.al., Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size., Nature communications, 2014, 5

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• fetal growth retardation_Wdr62<Gt(AF0003)Wtsi>/Wdr62<Gt(AF0003)Wtsi>
  http://metadb.riken.jp/0004201I129P2OlaHsd129S1SvImJWdr62GtAF0003WtsiWdr62GtAF0003WtsiWdr62GtAF0003Wtsi
• abnormal mitotic spindle morphology_Wdr62<Gt(AF0003)Wtsi>/Wdr62<Gt(AF0003)Wtsi>
  http://metadb.riken.jp/0009760I129P2OlaHsd129S1SvImJWdr62GtAF0003WtsiWdr62GtAF0003WtsiWdr62GtAF0003Wtsi
• loss of cortex neurons_Wdr62<Gt(AF0003)Wtsi>/Wdr62<Gt(AF0003)Wtsi>
  http://metadb.riken.jp/0003241I129P2OlaHsd129S1SvImJWdr62GtAF0003WtsiWdr62GtAF0003WtsiWdr62GtAF0003Wtsi
• decreased neuronal precursor cell number_Wdr62<Gt(AF0003)Wtsi>/Wdr62<Gt(AF0003)Wtsi>
  http://metadb.riken.jp/0004981I129P2OlaHsd129S1SvImJWdr62GtAF0003WtsiWdr62GtAF0003WtsiWdr62GtAF0003Wtsi
• thin cerebral cortex_Wdr62<Gt(AF0003)Wtsi>/Wdr62<Gt(AF0003)Wtsi>
  http://metadb.riken.jp/0006254I129P2OlaHsd129S1SvImJWdr62GtAF0003WtsiWdr62GtAF0003WtsiWdr62GtAF0003Wtsi
• reduced fertility_Wdr62<Gt(AF0003)Wtsi>/Wdr62<Gt(AF0003)Wtsi>
  http://metadb.riken.jp/0001921I129P2OlaHsd129S1SvImJWdr62GtAF0003WtsiWdr62GtAF0003WtsiWdr62GtAF0003Wtsi
• increased cell death_Wdr62<Gt(AF0003)Wtsi>/Wdr62<Gt(AF0003)Wtsi>
  http://metadb.riken.jp/0012556I129P2OlaHsd129S1SvImJWdr62GtAF0003WtsiWdr62GtAF0003WtsiWdr62GtAF0003Wtsi
• microcephaly_Wdr62<Gt(AF0003)Wtsi>/Wdr62<Gt(AF0003)Wtsi>
  http://metadb.riken.jp/0000433I129P2OlaHsd129S1SvImJWdr62GtAF0003WtsiWdr62GtAF0003WtsiWdr62GtAF0003Wtsi
• abnormal mitosis_Wdr62<Gt(AF0003)Wtsi>/Wdr62<Gt(AF0003)Wtsi>
  http://metadb.riken.jp/0004046I129P2OlaHsd129S1SvImJWdr62GtAF0003WtsiWdr62GtAF0003WtsiWdr62GtAF0003Wtsi
• abnormal nervous system physiology_Wdr62<Gt(AF0003)Wtsi>/Wdr62<Gt(AF0003)Wtsi>
  http://metadb.riken.jp/0003633I129P2OlaHsd129S1SvImJWdr62GtAF0003WtsiWdr62GtAF0003WtsiWdr62GtAF0003Wtsi
• proportional dwarf_Wdr62<Gt(AF0003)Wtsi>/Wdr62<Gt(AF0003)Wtsi>
  http://metadb.riken.jp/0008974I129P2OlaHsd129S1SvImJWdr62GtAF0003WtsiWdr62GtAF0003WtsiWdr62GtAF0003Wtsi
• abnormal mitotic spindle assembly checkpoint_Wdr62<Gt(AF0003)Wtsi>/Wdr62<Gt(AF0003)Wtsi>
  http://metadb.riken.jp/0009762I129P2OlaHsd129S1SvImJWdr62GtAF0003WtsiWdr62GtAF0003WtsiWdr62GtAF0003Wtsi