Léon. Kautz, et.al., Identification of erythroferrone as an erythroid regulator of iron metabolism., Nature genetics, 2014, 46

http://rdf.ncbi.nlm.nih.gov/pubmed/24880340

Léon. Kautz, et.al., Identification of erythroferrone as an erythroid regulator of iron metabolism., Nature genetics, 2014, 46

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased circulating iron level_Erfe<tm1Lex>/Erfe<tm1Lex>
  http://metadb.riken.jp/0004151B6129S5Erfetm1LexMmucdErfetm1LexErfetm1LexErfetm1Lex
• anemia_Hbb-b1<tm1Unc>/Hbb-b1<+>,Hbb-b2<tm1Unc>/Hbb-b2<+>
  http://metadb.riken.jp/0001577B6129P2Hbbb1tm1UncHbbb2tm1UncJHbbb1tm1UncHbbb1Hbbb2tm1UncHbbb2Hbbb2Hbbb1tm1UncHbbb2tm1UncHbbb1
• abnormal liver physiology_Erfe<tm1Lex>/Erfe<tm1Lex>
  http://metadb.riken.jp/0000609B6129S5Erfetm1LexMmucdErfetm1LexErfetm1LexErfetm1Lex
• abnormal bone marrow morphology_Hbb-b1<tm1Unc>/Hbb-b1<+>,Hbb-b2<tm1Unc>/Hbb-b2<+>
  http://metadb.riken.jp/0002397B6129P2Hbbb1tm1UncHbbb2tm1UncJHbbb1tm1UncHbbb1Hbbb2tm1UncHbbb2Hbbb2Hbbb1tm1UncHbbb2tm1UncHbbb1
• decreased mean corpuscular volume_Erfe<tm1Lex>/Erfe<tm1Lex>
  http://metadb.riken.jp/0002591B6129S5Erfetm1LexMmucdErfetm1LexErfetm1LexErfetm1Lex
• decreased hematocrit_Erfe<tm1Lex>/Erfe<tm1Lex>
  http://metadb.riken.jp/0000208B6129S5Erfetm1LexMmucdErfetm1LexErfetm1LexErfetm1Lex
• decreased hemoglobin content_Erfe<tm1Lex>/Erfe<tm1Lex>
  http://metadb.riken.jp/0002874B6129S5Erfetm1LexMmucdErfetm1LexErfetm1LexErfetm1Lex
• decreased mean corpuscular hemoglobin concentration_Erfe<tm1Lex>/Erfe<tm1Lex>
  http://metadb.riken.jp/0005642B6129S5Erfetm1LexMmucdErfetm1LexErfetm1LexErfetm1Lex
• decreased circulating iron level_Erfe<tm1Lex>/Erfe<tm1Lex>,Hbb-b1<tm1Unc>/Hbb-b1<+>,Hbb-b2<tm1Unc>/Hbb-b2<+>
  http://metadb.riken.jp/0004151I129P2OlaHsd129S5SvEvBrdC57BL6Erfetm1LexErfetm1LexHbbb1tm1UncHbbb1Hbbb2tm1UncHbbb2Hbbb1Erfetm1LexHbbb2Hbbb2tm1UncHbbb1tm1Unc
• decreased mean corpuscular hemoglobin_Erfe<tm1Lex>/Erfe<tm1Lex>,Hbb-b1<tm1Unc>/Hbb-b1<+>,Hbb-b2<tm1Unc>/Hbb-b2<+>
  http://metadb.riken.jp/0005562I129P2OlaHsd129S5SvEvBrdC57BL6Erfetm1LexErfetm1LexHbbb1tm1UncHbbb1Hbbb2tm1UncHbbb2Hbbb1Erfetm1LexHbbb2Hbbb2tm1UncHbbb1tm1Unc
• decreased hemoglobin content_Erfe<tm1Lex>/Erfe<+>
  http://metadb.riken.jp/0002874B6129S5Erfetm1LexMmucdErfetm1LexErfeErfetm1LexErfe
• decreased mean corpuscular volume_Erfe<tm1Lex>/Erfe<tm1Lex>,Hbb-b1<tm1Unc>/Hbb-b1<+>,Hbb-b2<tm1Unc>/Hbb-b2<+>
  http://metadb.riken.jp/0002591I129P2OlaHsd129S5SvEvBrdC57BL6Erfetm1LexErfetm1LexHbbb1tm1UncHbbb1Hbbb2tm1UncHbbb2Hbbb1Erfetm1LexHbbb2Hbbb2tm1UncHbbb1tm1Unc
• abnormal spleen morphology_Hbb-b1<tm1Unc>/Hbb-b1<+>,Hbb-b2<tm1Unc>/Hbb-b2<+>
  http://metadb.riken.jp/0000689B6129P2Hbbb1tm1UncHbbb2tm1UncJHbbb1tm1UncHbbb1Hbbb2tm1UncHbbb2Hbbb2Hbbb1tm1UncHbbb2tm1UncHbbb1
• abnormal hormone level_Erfe<tm1Lex>/Erfe<tm1Lex>,Hbb-b1<tm1Unc>/Hbb-b1<+>,Hbb-b2<tm1Unc>/Hbb-b2<+>
  http://metadb.riken.jp/0003953I129P2OlaHsd129S5SvEvBrdC57BL6Erfetm1LexErfetm1LexHbbb1tm1UncHbbb1Hbbb2tm1UncHbbb2Hbbb1Erfetm1LexHbbb2Hbbb2tm1UncHbbb1tm1Unc
• decreased liver iron level_Erfe<tm1Lex>/Erfe<tm1Lex>,Hbb-b1<tm1Unc>/Hbb-b1<+>,Hbb-b2<tm1Unc>/Hbb-b2<+>
  http://metadb.riken.jp/0008743I129P2OlaHsd129S5SvEvBrdC57BL6Erfetm1LexErfetm1LexHbbb1tm1UncHbbb1Hbbb2tm1UncHbbb2Hbbb1Erfetm1LexHbbb2Hbbb2tm1UncHbbb1tm1Unc
• increased circulating erythropoietin level_Hbb-b1<tm1Unc>/Hbb-b1<+>,Hbb-b2<tm1Unc>/Hbb-b2<+>
  http://metadb.riken.jp/0011285B6129P2Hbbb1tm1UncHbbb2tm1UncJHbbb1tm1UncHbbb1Hbbb2tm1UncHbbb2Hbbb2Hbbb1tm1UncHbbb2tm1UncHbbb1
• abnormal liver physiology_Erfe<tm1Lex>/Erfe<+>
  http://metadb.riken.jp/0000609B6129S5Erfetm1LexMmucdErfetm1LexErfeErfetm1LexErfe
• increased susceptibility to injury_Erfe<tm1Lex>/Erfe<tm1Lex>
  http://metadb.riken.jp/0005165B6129S5Erfetm1LexMmucdErfetm1LexErfetm1LexErfetm1Lex
• decreased mean corpuscular hemoglobin_Erfe<tm1Lex>/Erfe<tm1Lex>
  http://metadb.riken.jp/0005562B6129S5Erfetm1LexMmucdErfetm1LexErfetm1LexErfetm1Lex