Jingmin. Ji, et.al., Increased protein kinase C gamma activity induces Purkinje cell pathology in a mouse model of spinocerebellar ataxia 14., Neurobiology of disease, 2014, 70

http://rdf.ncbi.nlm.nih.gov/pubmed/24937631

Jingmin. Ji, et.al., Increased protein kinase C gamma activity induces Purkinje cell pathology in a mouse model of spinocerebellar ataxia 14., Neurobiology of disease, 2014, 70

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-PRKCG*S361G,-GFP)3Jpka
  http://metadb.riken.jp/db/mgi_rdf/MGI:5660027

class

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-PRKCG*S361G,-GFP)3Jpka
  http://metadb.riken.jp/db/mgi_rdf/MGI:5660027

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• ataxia_Tg(Pcp2-tTA)3Horr/0,Tg(tetO-PRKCG*S361G,-GFP)3Jpka/0
  http://metadb.riken.jp/0001393IFVBNTgPcp2tTA3Horr0TgtetOPRKCGS361GGFP3Jpka0TgtetOPRKCGS361GGFP3JpkaTgPcp2tTA3Horr
• Purkinje cell degeneration_Tg(Pcp2-tTA)3Horr/0,Tg(tetO-PRKCG*S361G,-GFP)3Jpka/0
  http://metadb.riken.jp/0000876IFVBNTgPcp2tTA3Horr0TgtetOPRKCGS361GGFP3Jpka0TgtetOPRKCGS361GGFP3JpkaTgPcp2tTA3Horr
• abnormal cerebellar Purkinje cell layer_Tg(Pcp2-tTA)3Horr/0,Tg(tetO-PRKCG*S361G,-GFP)3Jpka/0
  http://metadb.riken.jp/0000875IFVBNTgPcp2tTA3Horr0TgtetOPRKCGS361GGFP3Jpka0TgtetOPRKCGS361GGFP3JpkaTgPcp2tTA3Horr
• impaired coordination_Tg(Pcp2-tTA)3Horr/0,Tg(tetO-PRKCG*S361G,-GFP)3Jpka/0
  http://metadb.riken.jp/0001405IFVBNTgPcp2tTA3Horr0TgtetOPRKCGS361GGFP3Jpka0TgtetOPRKCGS361GGFP3JpkaTgPcp2tTA3Horr
• abnormal Purkinje cell dendrite morphology_Tg(Pcp2-tTA)3Horr/0,Tg(tetO-PRKCG*S361G,-GFP)3Jpka/0
  http://metadb.riken.jp/0008572IFVBNTgPcp2tTA3Horr0TgtetOPRKCGS361GGFP3Jpka0TgtetOPRKCGS361GGFP3JpkaTgPcp2tTA3Horr
• decreased Purkinje cell number_Tg(Pcp2-tTA)3Horr/0,Tg(tetO-PRKCG*S361G,-GFP)3Jpka/0
  http://metadb.riken.jp/0000880IFVBNTgPcp2tTA3Horr0TgtetOPRKCGS361GGFP3Jpka0TgtetOPRKCGS361GGFP3JpkaTgPcp2tTA3Horr