Jaime L. Schneider, et.al., Deficient chaperone-mediated autophagy in liver leads to metabolic dysregulation., Cell metabolism, 2014, 20

http://rdf.ncbi.nlm.nih.gov/pubmed/25043815

Jaime L. Schneider, et.al., Deficient chaperone-mediated autophagy in liver leads to metabolic dysregulation., Cell metabolism, 2014, 20

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Lamp2<tm1Amcu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5617956

class

http://purl.org/net/cito/citesAsAuthority

• Lamp2<tm1Amcu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5617956

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• pale liver_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0000603I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• decreased liver glycogen level_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0010398I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• abnormal lipid homeostasis_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002118I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• increased circulating alanine transaminase level_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002941I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• abnormal autophagy_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0008260I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• decreased white fat cell lipid droplet size_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0009122I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• decreased hepatic glucose production_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0020103I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• decreased brown fat cell lipid droplet size_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0009125I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• abnormal liver physiology_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0000609I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• increased susceptibility to weight gain_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005455I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• increased oxygen consumption_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005289I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• weight loss_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0001263I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• increased hepatocyte apoptosis_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0003887I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• abnormal enzyme/coenzyme activity_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005584I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• enlarged liver_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0000599I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• decreased liver function_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0003325I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• abnormal glucose homeostasis_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002078I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• decreased fasted circulating glucose level_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0013278I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• increased liver weight_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002981I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• decreased body weight_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0001262I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• decreased percent body fat/body weight_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005459I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• enhanced behavioral response to xenobiotic_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0009746I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• decreased gonadal fat pad weight_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0009283I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• hepatic steatosis_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002628I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• increased energy expenditure_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0004889I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• increased respiratory quotient_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0010378I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• increased liver triglyceride level_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0009355I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• enhanced cellular glucose import_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0003927I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• improved glucose tolerance_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005292I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• increased carbon dioxide production_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0008963I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu
• hypoactivity_Lamp2<tm1Amcu>/Y,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0001402I129S6SvEvTacC57BL6C57BL6JLamp2tm1AmcuYTgAlbcre21Mgn0TgAlbcre21MgnLamp2tm1Amcu