Beth A. Firulli, et.al., Hand1 phosphoregulation within the distal arch neural crest is essential for craniofacial morphogenesis., Development (Cambridge, England), 2014, 141

http://rdf.ncbi.nlm.nih.gov/pubmed/25053435

Beth A. Firulli, et.al., Hand1 phosphoregulation within the distal arch neural crest is essential for craniofacial morphogenesis., Development (Cambridge, England), 2014, 141

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Hand1<tm4Abfi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5604131
• Hand1<tm3Abfi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5604130

class

http://purl.org/net/cito/citesAsAuthority

• Hand1<tm4Abfi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5604131
• Hand1<tm3Abfi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5604130

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• mandible hypoplasia_Hand1<tm2Eno>/Hand1<tm4Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0000460I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm4AbfiTgWnt1cre2Sor0Hand1tm2EnoTgWnt1cre2SorHand1tm4Abfi
• abnormal basicranium morphology_Hand1<tm3Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0010029IC3HC57BL6Hand1tm3AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm3AbfiTgWnt1cre2Sor
• decreased maxillary shelf size_Hand1<tm2Eno>/Hand1<tm4Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0009897I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm4AbfiTgWnt1cre2Sor0Hand1tm2EnoTgWnt1cre2SorHand1tm4Abfi
• abnormal nasal capsule morphology_Hand1<tm2Eno>/Hand1<tm4Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0004726I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm4AbfiTgWnt1cre2Sor0Hand1tm2EnoTgWnt1cre2SorHand1tm4Abfi
• basisphenoid bone hypoplasia_Hand1<tm2Eno>/Hand1<tm3Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0004461I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm3AbfiTgWnt1cre2Sor0Hand1tm3AbfiTgWnt1cre2SorHand1tm2Eno
• abnormal secondary palate development_Hand1<tm2Eno>/Hand1<tm4Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0009655I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm4AbfiTgWnt1cre2Sor0Hand1tm2EnoTgWnt1cre2SorHand1tm4Abfi
• mandible hypoplasia_Hand1<tm3Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0000460IC3HC57BL6Hand1tm3AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm3AbfiTgWnt1cre2Sor
• absent nasal bone_Hand1<tm3Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0004473IC3HC57BL6Hand1tm3AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm3AbfiTgWnt1cre2Sor
• abnormal premaxilla morphology_Hand1<tm4Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0002820IC3HC57BL6Hand1tm4AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm4AbfiTgWnt1cre2Sor
• abnormal craniofacial development_Hand1<tm2Eno>/Hand1<tm3Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0003935I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm3AbfiTgWnt1cre2Sor0Hand1tm3AbfiTgWnt1cre2SorHand1tm2Eno
• abnormal squamosal bone morphology_Hand1<tm4Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0004423IC3HC57BL6Hand1tm4AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm4AbfiTgWnt1cre2Sor
• abnormal nasal capsule morphology_Hand1<tm3Abfi>/Hand1<+>,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0004726NSHand1tm3AbfiHand1TgMpzcre94Imeg0Hand1tm3AbfiTgMpzcre94ImegHand1
• midline facial cleft_Hand1<tm4Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0000108IC3HC57BL6Hand1tm4AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm4AbfiTgWnt1cre2Sor
• abnormal pharyngeal arch morphology_Hand1<tm4Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0002884IC3HC57BL6Hand1tm4AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm4AbfiTgWnt1cre2Sor
• nasal bone hypoplasia_Hand1<tm4Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0000103IC3HC57BL6Hand1tm4AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm4AbfiTgWnt1cre2Sor
• abnormal pharyngeal arch morphology_Hand1<tm2Eno>/Hand1<tm3Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0002884I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm3AbfiTgWnt1cre2Sor0Hand1tm3AbfiTgWnt1cre2SorHand1tm2Eno
• decreased palatine bone horizontal plate size_Hand1<tm2Eno>/Hand1<tm4Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0009895I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm4AbfiTgWnt1cre2Sor0Hand1tm2EnoTgWnt1cre2SorHand1tm4Abfi
• absent nasal septum_Hand1<tm3Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0004872IC3HC57BL6Hand1tm3AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm3AbfiTgWnt1cre2Sor
• abnormal tongue morphology_Hand1<tm4Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0000762IC3HC57BL6Hand1tm4AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm4AbfiTgWnt1cre2Sor
• abnormal alisphenoid bone morphology_Hand1<tm3Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0003235IC3HC57BL6Hand1tm3AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm3AbfiTgWnt1cre2Sor
• absent nasal septum_Hand1<tm2Eno>/Hand1<tm4Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0004872I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm4AbfiTgWnt1cre2Sor0Hand1tm2EnoTgWnt1cre2SorHand1tm4Abfi
• abnormal tongue morphology_Hand1<tm2Eno>/Hand1<tm3Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0000762I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm3AbfiTgWnt1cre2Sor0Hand1tm3AbfiTgWnt1cre2SorHand1tm2Eno
• abnormal maxillary prominence morphology_Hand1<tm2Eno>/Hand1<tm4Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0010940I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm4AbfiTgWnt1cre2Sor0Hand1tm2EnoTgWnt1cre2SorHand1tm4Abfi
• abnormal palatal shelf fusion at midline_Hand1<tm2Eno>/Hand1<tm3Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0009887I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm3AbfiTgWnt1cre2Sor0Hand1tm3AbfiTgWnt1cre2SorHand1tm2Eno
• small nasal bone_Hand1<tm3Abfi>/Hand1<+>,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0004470NSHand1tm3AbfiHand1TgMpzcre94Imeg0Hand1tm3AbfiTgMpzcre94ImegHand1
• abnormal Reichert's cartilage morphology_Hand1<tm3Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0004915IC3HC57BL6Hand1tm3AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm3AbfiTgWnt1cre2Sor
• abnormal nasal capsule morphology_Hand1<tm2Eno>/Hand1<tm3Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0004726I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm3AbfiTgWnt1cre2Sor0Hand1tm3AbfiTgWnt1cre2SorHand1tm2Eno
• small frontal bone_Hand1<tm3Abfi>/Hand1<+>,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0004377NSHand1tm3AbfiHand1TgMpzcre94Imeg0Hand1tm3AbfiTgMpzcre94ImegHand1
• abnormal nasal capsule morphology_Hand1<tm4Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0004726IC3HC57BL6Hand1tm4AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm4AbfiTgWnt1cre2Sor
• abnormal palatal shelf fusion at midline_Hand1<tm4Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0009887IC3HC57BL6Hand1tm4AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm4AbfiTgWnt1cre2Sor
• abnormal basisphenoid bone morphology_Hand1<tm3Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0000106IC3HC57BL6Hand1tm3AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm3AbfiTgWnt1cre2Sor
• neonatal lethality_Hand1<tm3Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0002058IC3HC57BL6Hand1tm3AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm3AbfiTgWnt1cre2Sor
• abnormal secondary palate development_Hand1<tm3Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0009655IC3HC57BL6Hand1tm3AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm3AbfiTgWnt1cre2Sor
• abnormal Meckel's cartilage morphology_Hand1<tm3Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0005587IC3HC57BL6Hand1tm3AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm3AbfiTgWnt1cre2Sor
• abnormal palatal shelf fusion at midline_Hand1<tm2Eno>/Hand1<tm4Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0009887I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm4AbfiTgWnt1cre2Sor0Hand1tm2EnoTgWnt1cre2SorHand1tm4Abfi
• abnormal alisphenoid bone morphology_Hand1<tm4Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0003235IC3HC57BL6Hand1tm4AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm4AbfiTgWnt1cre2Sor
• short premaxilla_Hand1<tm3Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0000091IC3HC57BL6Hand1tm3AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm3AbfiTgWnt1cre2Sor
• neonatal lethality_Hand1<tm2Eno>/Hand1<tm3Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0002058I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm3AbfiTgWnt1cre2Sor0Hand1tm3AbfiTgWnt1cre2SorHand1tm2Eno
• abnormal pharyngeal arch morphology_Hand1<tm3Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0002884IC3HC57BL6Hand1tm3AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm3AbfiTgWnt1cre2Sor
• neonatal lethality_Hand1<tm4Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0002058IC3HC57BL6Hand1tm4AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm4AbfiTgWnt1cre2Sor
• abnormal tongue morphology_Hand1<tm3Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0000762IC3HC57BL6Hand1tm3AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm3AbfiTgWnt1cre2Sor
• midline facial cleft_Hand1<tm2Eno>/Hand1<tm4Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0000108I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm4AbfiTgWnt1cre2Sor0Hand1tm2EnoTgWnt1cre2SorHand1tm4Abfi
• midline facial cleft_Hand1<tm2Eno>/Hand1<tm3Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0000108I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm3AbfiTgWnt1cre2Sor0Hand1tm3AbfiTgWnt1cre2SorHand1tm2Eno
• abnormal zygomatic bone morphology_Hand1<tm3Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0005270IC3HC57BL6Hand1tm3AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm3AbfiTgWnt1cre2Sor
• abnormal palate development_Hand1<tm3Abfi>/Hand1<+>,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0009653NSHand1tm3AbfiHand1TgMpzcre94Imeg0Hand1tm3AbfiTgMpzcre94ImegHand1
• abnormal craniofacial development_Hand1<tm2Eno>/Hand1<tm4Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0003935I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm4AbfiTgWnt1cre2Sor0Hand1tm2EnoTgWnt1cre2SorHand1tm4Abfi
• abnormal maxilla morphology_Hand1<tm3Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0000455IC3HC57BL6Hand1tm3AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm3AbfiTgWnt1cre2Sor
• nasal bone hypoplasia_Hand1<tm2Eno>/Hand1<tm3Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0000103I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm3AbfiTgWnt1cre2Sor0Hand1tm3AbfiTgWnt1cre2SorHand1tm2Eno
• abnormal secondary palate development_Hand1<tm2Eno>/Hand1<tm3Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0009655I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm3AbfiTgWnt1cre2Sor0Hand1tm3AbfiTgWnt1cre2SorHand1tm2Eno
• abnormal pterygoid bone morphology_Hand1<tm3Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0004453IC3HC57BL6Hand1tm3AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm3AbfiTgWnt1cre2Sor
• neonatal lethality_Hand1<tm2Eno>/Hand1<tm4Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0002058I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm4AbfiTgWnt1cre2Sor0Hand1tm2EnoTgWnt1cre2SorHand1tm4Abfi
• absent nasal septum_Hand1<tm2Eno>/Hand1<tm3Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0004872I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm3AbfiTgWnt1cre2Sor0Hand1tm3AbfiTgWnt1cre2SorHand1tm2Eno
• frontal bone hypoplasia_Hand1<tm3Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0004869IC3HC57BL6Hand1tm3AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm3AbfiTgWnt1cre2Sor
• abnormal pharyngeal arch morphology_Hand1<tm2Eno>/Hand1<tm4Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0002884I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm4AbfiTgWnt1cre2Sor0Hand1tm2EnoTgWnt1cre2SorHand1tm4Abfi
• abnormal palatal shelf fusion at midline_Hand1<tm3Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0009887IC3HC57BL6Hand1tm3AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm3AbfiTgWnt1cre2Sor
• abnormal nasal capsule morphology_Hand1<tm3Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0004726IC3HC57BL6Hand1tm3AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm3AbfiTgWnt1cre2Sor
• abnormal sagittal suture morphology_Hand1<tm3Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0003843IC3HC57BL6Hand1tm3AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm3AbfiTgWnt1cre2Sor
• abnormal squamosal bone morphology_Hand1<tm2Eno>/Hand1<tm4Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0004423I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm4AbfiTgWnt1cre2Sor0Hand1tm2EnoTgWnt1cre2SorHand1tm4Abfi
• absent squamosal bone_Hand1<tm3Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0004899IC3HC57BL6Hand1tm3AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm3AbfiTgWnt1cre2Sor
• small mandible_Hand1<tm4Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0004592IC3HC57BL6Hand1tm4AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm4AbfiTgWnt1cre2Sor
• abnormal middle ear ossicle morphology_Hand1<tm2Eno>/Hand1<tm4Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0005105I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm4AbfiTgWnt1cre2Sor0Hand1tm2EnoTgWnt1cre2SorHand1tm4Abfi
• interparietal bone hypoplasia_Hand1<tm3Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0004385IC3HC57BL6Hand1tm3AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm3AbfiTgWnt1cre2Sor
• absent nasal septum_Hand1<tm4Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0004872IC3HC57BL6Hand1tm4AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm4AbfiTgWnt1cre2Sor
• midline facial cleft_Hand1<tm3Abfi>/Hand1<+>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0000108IC3HC57BL6Hand1tm3AbfiHand1TgWnt1cre2Sor0Hand1Hand1tm3AbfiTgWnt1cre2Sor
• abnormal maxillary prominence morphology_Hand1<tm2Eno>/Hand1<tm3Abfi>,Tg(Wnt1-cre)2Sor/0
  http://metadb.riken.jp/0010940I129S6SvEvTacC3HC57BL6Hand1tm2EnoHand1tm3AbfiTgWnt1cre2Sor0Hand1tm3AbfiTgWnt1cre2SorHand1tm2Eno