Shiyan. Yu, et.al., TLR sorting by Rab11 endosomes maintains intestinal epithelial-microbial homeostasis., The EMBO journal, 2014, 33

http://rdf.ncbi.nlm.nih.gov/pubmed/25063677

Shiyan. Yu, et.al., TLR sorting by Rab11 endosomes maintains intestinal epithelial-microbial homeostasis., The EMBO journal, 2014, 33

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Rab11a<tm1.1Ngao>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5608786

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased body size_Rab11a<tm1.1Ngao>/Rab11a<tm1.1Ngao>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0001265I129S6SvEvTacC57BL6JSJLRab11atm11NgaoRab11atm11NgaoTgVil1cre997Gum0TgVil1cre997GumRab11atm11Ngao
• decreased colon length_Rab11a<tm1.1Ngao>/Rab11a<tm1.1Ngao>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0013956I129S6SvEvTacC57BL6JSJLRab11atm11NgaoRab11atm11NgaoTgVil1cre997Gum0TgVil1cre997GumRab11atm11Ngao
• decreased small intestinal villus size_Rab11a<tm1.1Ngao>/Rab11a<tm1.1Ngao>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0008142I129S6SvEvTacC57BL6JSJLRab11atm11NgaoRab11atm11NgaoTgVil1cre997Gum0TgVil1cre997GumRab11atm11Ngao
• increased interleukin-6 secretion_Rab11a<tm1.1Ngao>/Rab11a<tm1.1Ngao>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0008705I129S6SvEvTacC57BL6DBA2Rab11atm11NgaoRab11atm11NgaoTgVilcreERT223Syr0Rab11atm11NgaoTgVilcreERT223Syr
• abnormal small intestinal villus morphology_Rab11a<tm1.1Ngao>/Rab11a<tm1.1Ngao>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0008108I129S6SvEvTacC57BL6JSJLRab11atm11NgaoRab11atm11NgaoTgVil1cre997Gum0TgVil1cre997GumRab11atm11Ngao
• abnormal crypts of Lieberkuhn morphology_Rab11a<tm1.1Ngao>/Rab11a<tm1.1Ngao>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0000490I129S6SvEvTacC57BL6JSJLRab11atm11NgaoRab11atm11NgaoTgVil1cre997Gum0TgVil1cre997GumRab11atm11Ngao
• abnormal cytokine secretion_Rab11a<tm1.1Ngao>/Rab11a<tm1.1Ngao>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0003009I129S6SvEvTacC57BL6JSJLRab11atm11NgaoRab11atm11NgaoTgVil1cre997Gum0TgVil1cre997GumRab11atm11Ngao
• abnormal digestive system physiology_Rab11a<tm1.1Ngao>/Rab11a<tm1.1Ngao>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0001663I129S6SvEvTacC57BL6JSJLRab11atm11NgaoRab11atm11NgaoTgVil1cre997Gum0TgVil1cre997GumRab11atm11Ngao
• abnormal intestinal epithelium morphology_Rab11a<tm1.1Ngao>/Rab11a<tm1.1Ngao>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0000488I129S6SvEvTacC57BL6JSJLRab11atm11NgaoRab11atm11NgaoTgVil1cre997Gum0TgVil1cre997GumRab11atm11Ngao
• increased interleukin-1 beta secretion_Rab11a<tm1.1Ngao>/Rab11a<tm1.1Ngao>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0008657I129S6SvEvTacC57BL6JSJLRab11atm11NgaoRab11atm11NgaoTgVil1cre997Gum0TgVil1cre997GumRab11atm11Ngao
• abnormal intestinal goblet cell morphology_Rab11a<tm1.1Ngao>/Rab11a<tm1.1Ngao>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0003449I129S6SvEvTacC57BL6JSJLRab11atm11NgaoRab11atm11NgaoTgVil1cre997Gum0TgVil1cre997GumRab11atm11Ngao
• increased interleukin-6 secretion_Rab11a<tm1.1Ngao>/Rab11a<tm1.1Ngao>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0008705I129S6SvEvTacC57BL6JSJLRab11atm11NgaoRab11atm11NgaoTgVil1cre997Gum0TgVil1cre997GumRab11atm11Ngao
• premature death_Rab11a<tm1.1Ngao>/Rab11a<tm1.1Ngao>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0002083I129S6SvEvTacC57BL6JSJLRab11atm11NgaoRab11atm11NgaoTgVil1cre997Gum0TgVil1cre997GumRab11atm11Ngao
• abnormal intestinal epithelium morphology_Rab11a<tm1.1Ngao>/Rab11a<tm1.1Ngao>,Lgr5<tm1(cre/ERT2)Cle>/Lgr5<+>
  http://metadb.riken.jp/0000488I129P2OlaHsd129S6SvEvTacRab11atm11NgaoRab11atm11NgaoLgr5tm1creERT2CleLgr5Rab11atm11NgaoLgr5tm1creERT2CleLgr5
• intestinal inflammation_Rab11a<tm1.1Ngao>/Rab11a<tm1.1Ngao>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0001858I129S6SvEvTacC57BL6JSJLRab11atm11NgaoRab11atm11NgaoTgVil1cre997Gum0TgVil1cre997GumRab11atm11Ngao
• postnatal lethality, incomplete penetrance_Rab11a<tm1.1Ngao>/Rab11a<tm1.1Ngao>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0011086I129S6SvEvTacC57BL6JSJLRab11atm11NgaoRab11atm11NgaoTgVil1cre997Gum0TgVil1cre997GumRab11atm11Ngao
• abnormal small intestinal crypt cell proliferation_Rab11a<tm1.1Ngao>/Rab11a<tm1.1Ngao>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0010157I129S6SvEvTacC57BL6DBA2Rab11atm11NgaoRab11atm11NgaoTgVilcreERT223Syr0Rab11atm11NgaoTgVilcreERT223Syr
• abnormal intestine morphology_Rab11a<tm1.1Ngao>/Rab11a<tm1.1Ngao>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0000477I129S6SvEvTacC57BL6JSJLRab11atm11NgaoRab11atm11NgaoTgVil1cre997Gum0TgVil1cre997GumRab11atm11Ngao
• abnormal intestine physiology_Rab11a<tm1.1Ngao>/Rab11a<tm1.1Ngao>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0010155I129S6SvEvTacC57BL6JSJLRab11atm11NgaoRab11atm11NgaoTgVil1cre997Gum0TgVil1cre997GumRab11atm11Ngao
• abnormal small intestinal crypt cell proliferation_Rab11a<tm1.1Ngao>/Rab11a<tm1.1Ngao>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0010157I129S6SvEvTacC57BL6JSJLRab11atm11NgaoRab11atm11NgaoTgVil1cre997Gum0TgVil1cre997GumRab11atm11Ngao

class

http://purl.org/net/cito/citesAsAuthority

• Rab11a<tm1.1Ngao>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5608786