Sandro. Altamura, et.al., Resistance of ferroportin to hepcidin binding causes exocrine pancreatic failure and fatal iron overload., Cell metabolism, 2014, 20

http://rdf.ncbi.nlm.nih.gov/pubmed/25100063

Sandro. Altamura, et.al., Resistance of ferroportin to hepcidin binding causes exocrine pancreatic failure and fatal iron overload., Cell metabolism, 2014, 20

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5607257

class

http://purl.org/net/cito/citesAsAuthority

• Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5607257

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased heart iron level_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0020367I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• increased hemoglobin content_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0005564I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• decreased spleen iron level_Slc40a1<tm1.1Mmfe>/Slc40a1<+>
  http://metadb.riken.jp/0008808I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1Slc40a1tm11MmfeSlc40a1
• decreased circulating unsaturated transferrin level_Slc40a1<tm1.1Mmfe>/Slc40a1<+>
  http://metadb.riken.jp/0011897I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1Slc40a1tm11MmfeSlc40a1
• hemochromatosis_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0005638I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• oxidative stress_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0003674I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• cachexia_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0005150I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• increased circulating iron level_Slc40a1<tm1.1Mmfe>/Slc40a1<+>
  http://metadb.riken.jp/0008810I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1Slc40a1tm11MmfeSlc40a1
• abnormal iron homeostasis_Slc40a1<tm1.1Mmfe>/Slc40a1<+>
  http://metadb.riken.jp/0005637I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1Slc40a1tm11MmfeSlc40a1
• increased brain iron level_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0020365I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• increased circulating lipase level_Slc40a1<tm1.1Mmfe>/Slc40a1<+>
  http://metadb.riken.jp/0011886I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1Slc40a1tm11MmfeSlc40a1
• decreased circulating unsaturated transferrin level_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0011897I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• abnormal liver physiology_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0000609I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• abnormal enzyme/coenzyme level_Slc40a1<tm1.1Mmfe>/Slc40a1<+>
  http://metadb.riken.jp/0005319I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1Slc40a1tm11MmfeSlc40a1
• decreased intestinal iron level_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0020385I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• increased circulating iron level_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0008810I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• increased liver iron level_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0008807I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• increased liver iron level_Slc40a1<tm1.1Mmfe>/Slc40a1<+>
  http://metadb.riken.jp/0008807I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1Slc40a1tm11MmfeSlc40a1
• oxidative stress_Slc40a1<tm1.1Mmfe>/Slc40a1<+>
  http://metadb.riken.jp/0003674I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1Slc40a1tm11MmfeSlc40a1
• abnormal pancreatic acinar cell morphology_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0009146I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• increased pancreas iron level_Slc40a1<tm1.1Mmfe>/Slc40a1<+>
  http://metadb.riken.jp/0013302I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1Slc40a1tm11MmfeSlc40a1
• increased pancreas iron level_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0013302I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• increased erythrocyte cell number_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0003131I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• abnormal enzyme/coenzyme level_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0005319I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• increased hematocrit_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0002608I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• premature death_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• abnormal iron homeostasis_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0005637I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• increased kidney iron level_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0010375I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• increased circulating ferritin level_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0011890I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• increased circulating ferritin level_Slc40a1<tm1.1Mmfe>/Slc40a1<+>
  http://metadb.riken.jp/0011890I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1Slc40a1tm11MmfeSlc40a1
• increased mean corpuscular volume_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0002590I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• abnormal liver morphology_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0000598I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• abnormal pancreas morphology_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0001944I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• decreased spleen iron level_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0008808I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe
• increased circulating lipase level_Slc40a1<tm1.1Mmfe>/Slc40a1<tm1.1Mmfe>
  http://metadb.riken.jp/0011886I129P2OlaHsdC57BL6Slc40a1tm11MmfeSlc40a1tm11MmfeSlc40a1tm11Mmfe