Kathrin. Ikels, et.al., FTO is a relevant factor for the development of the metabolic syndrome in mice., PloS one, 2014, 9

http://rdf.ncbi.nlm.nih.gov/pubmed/25144618

Kathrin. Ikels, et.al., FTO is a relevant factor for the development of the metabolic syndrome in mice., PloS one, 2014, 9

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased interscapular fat pad weight_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0009294IC57BL6JLepobLepobLepob
• increased gonadal fat pad weight_Fto<tm1Urt>/Fto<tm1Urt>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0009285I129S1Sv129X1SvJC57BL6JFtotm1UrtFtotm1UrtLepobLepobLepobFtotm1Urt
• impaired glucose tolerance_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0005293IC57BL6JLepobLepobLepob
• increased fat cell size_Fto<tm1Urt>/Fto<tm1Urt>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0006094I129S1Sv129X1SvJC57BL6JFtotm1UrtFtotm1UrtLepobLepobLepobFtotm1Urt
• increased interscapular fat pad weight_Fto<tm1Urt>/Fto<tm1Urt>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0009294I129S1Sv129X1SvJC57BL6JFtotm1UrtFtotm1UrtLepobLepobLepobFtotm1Urt
• enlarged pancreatic islets_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0009171IC57BL6JLepobLepobLepob
• polyphagia_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0001433IC57BL6JLepobLepobLepob
• hepatic steatosis_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0002628IC57BL6JLepobLepobLepob
• insulin resistance_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0005331IC57BL6JLepobLepobLepob
• hypoactivity_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0001402IC57BL6JLepobLepobLepob
• increased gonadal fat pad weight_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0009285IC57BL6JLepobLepobLepob
• decreased body length_Fto<tm1Urt>/Fto<tm1Urt>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0001258I129S1Sv129X1SvJC57BL6JFtotm1UrtFtotm1UrtLepobLepobLepobFtotm1Urt
• increased percent body fat/body weight_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0005458IC57BL6JLepobLepobLepob
• increased fasted circulating glucose level_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0013279IC57BL6JLepobLepobLepob
• increased inguinal fat pad weight_Fto<tm1Urt>/Fto<tm1Urt>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0009292I129S1Sv129X1SvJC57BL6JFtotm1UrtFtotm1UrtLepobLepobLepobFtotm1Urt
• increased liver weight_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0002981IC57BL6JLepobLepobLepob
• enlarged pancreatic islets_Fto<tm1Urt>/Fto<tm1Urt>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0009171I129S1Sv129X1SvJC57BL6JFtotm1UrtFtotm1UrtLepobLepobLepobFtotm1Urt
• hypoactivity_Fto<tm1Urt>/Fto<tm1Urt>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0001402I129S1Sv129X1SvJC57BL6JFtotm1UrtFtotm1UrtLepobLepobLepobFtotm1Urt
• hepatic steatosis_Fto<tm1Urt>/Fto<tm1Urt>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0002628I129S1Sv129X1SvJC57BL6JFtotm1UrtFtotm1UrtLepobLepobLepobFtotm1Urt
• increased body length_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0001257IC57BL6JLepobLepobLepob
• insulin resistance_Fto<tm1Urt>/Fto<tm1Urt>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0005331I129S1Sv129X1SvJC57BL6JFtotm1UrtFtotm1UrtLepobLepobLepobFtotm1Urt
• postnatal lethality, incomplete penetrance_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0011086IC57BL6JLepobLepobLepob
• obese_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0001261IC57BL6JLepobLepobLepob
• increased inguinal fat pad weight_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0009292IC57BL6JLepobLepobLepob
• increased lean body mass_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0003960IC57BL6JLepobLepobLepob
• increased fat cell size_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0006094IC57BL6JLepobLepobLepob
• abnormal adipose tissue morphology_Fto<tm1Urt>/Fto<tm1Urt>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0000003I129S1Sv129X1SvJC57BL6JFtotm1UrtFtotm1UrtLepobLepobLepobFtotm1Urt
• increased liver weight_Fto<tm1Urt>/Fto<tm1Urt>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0002981I129S1Sv129X1SvJC57BL6JFtotm1UrtFtotm1UrtLepobLepobLepobFtotm1Urt
• increased percent body fat/body weight_Fto<tm1Urt>/Fto<tm1Urt>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0005458I129S1Sv129X1SvJC57BL6JFtotm1UrtFtotm1UrtLepobLepobLepobFtotm1Urt
• hyperglycemia_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0001559IC57BL6JLepobLepobLepob
• increased body weight_Fto<tm1Urt>/Fto<tm1Urt>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0001260I129S1Sv129X1SvJC57BL6JFtotm1UrtFtotm1UrtLepobLepobLepobFtotm1Urt

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased fasted circulating glucose level in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1011251
• increased lean body mass in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1011247
• increased inguinal fat pad weight in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1011249
• increased body length in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1011246
• increased gonadal fat pad weight in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1011248
• postnatal lethality, incomplete penetrance in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1011250