Xiufang. Xiong, et.al., Ribosomal protein S27-like is a physiological regulator of p53 that suppresses genomic instability and tumorigenesis., eLife, 2014, 3

http://rdf.ncbi.nlm.nih.gov/pubmed/25144937

Xiufang. Xiong, et.al., Ribosomal protein S27-like is a physiological regulator of p53 that suppresses genomic instability and tumorigenesis., eLife, 2014, 3

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• thymus hypoplasia_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>
  http://metadb.riken.jp/0001823I129C57BL6NRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7Tigm
• decreased bone marrow cell number_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>
  http://metadb.riken.jp/0000333C57BL6Rps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7Tigm
• liver hypoplasia_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>
  http://metadb.riken.jp/0000600C57BL6Rps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7Tigm
• premature death_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002083I129S2SvPasC57BL6NRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmTrp53tm1TyjTrp53Trp53tm1TyjTrp53Rps27lGtIST11658B7Tigm
• decreased hematopoietic stem cell number_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>
  http://metadb.riken.jp/0004810C57BL6Rps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7Tigm
• decreased bone marrow cell number_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>
  http://metadb.riken.jp/0000333I129C57BL6NRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7Tigm
• decreased body size_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>
  http://metadb.riken.jp/0001265C57BL6Rps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7Tigm
• spleen hypoplasia_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>
  http://metadb.riken.jp/0000694I129C57BL6NRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7Tigm
• decreased spleen weight_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>
  http://metadb.riken.jp/0004953C57BL6Rps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7Tigm
• enlarged liver_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0000599I129S2SvPasC57BL6NRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmTrp53tm1TyjTrp53Trp53tm1TyjTrp53Rps27lGtIST11658B7Tigm
• decreased body weight_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>
  http://metadb.riken.jp/0001262C57BL6Rps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7Tigm
• premature death_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>
  http://metadb.riken.jp/0002083I129S2SvPasC57BL6NRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7Tigm
• thymus cortex hypoplasia_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>
  http://metadb.riken.jp/0000711C57BL6Rps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7Tigm
• increased thymocyte apoptosis_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>
  http://metadb.riken.jp/0009541C57BL6Rps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7Tigm
• abnormal hematopoietic stem cell physiology_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>
  http://metadb.riken.jp/0010763C57BL6Rps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7Tigm
• enlarged spleen_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0000691I129S2SvPasC57BL6NRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmTrp53tm1TyjTrp53Trp53tm1TyjTrp53Rps27lGtIST11658B7Tigm
• decreased bone marrow cell number_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0000333I129S2SvPasC57BL6NRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmTrp53tm1TyjTrp53Trp53tm1TyjTrp53Rps27lGtIST11658B7Tigm
• postnatal lethality, complete penetrance_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>
  http://metadb.riken.jp/0011085C57BL6Rps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7Tigm
• premature death_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>
  http://metadb.riken.jp/0002083I129C57BL6NRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7Tigm
• aneuploidy_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0004024I129S2SvPasC57BL6NRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmTrp53tm1TyjTrp53Trp53tm1TyjTrp53Rps27lGtIST11658B7Tigm
• chromosomal instability_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0008866I129S2SvPasC57BL6NRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmTrp53tm1TyjTrp53Trp53tm1TyjTrp53Rps27lGtIST11658B7Tigm
• decreased thymus weight_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>
  http://metadb.riken.jp/0004956C57BL6Rps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7Tigm
• decreased common myeloid progenitor cell number_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>
  http://metadb.riken.jp/0008813C57BL6Rps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7Tigm
• increased B cell derived lymphoma incidence_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002023I129S2SvPasC57BL6NRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmTrp53tm1TyjTrp53Trp53tm1TyjTrp53Rps27lGtIST11658B7Tigm
• increased T cell derived lymphoma incidence_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002024I129S2SvPasC57BL6NRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmTrp53tm1TyjTrp53Trp53tm1TyjTrp53Rps27lGtIST11658B7Tigm
• increased lymphoma incidence_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0012431I129S2SvPasC57BL6NRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmTrp53tm1TyjTrp53tm1TyjRps27lGtIST11658B7TigmTrp53tm1Tyj
• postnatal lethality, incomplete penetrance_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>
  http://metadb.riken.jp/0011086I129C57BL6NRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7Tigm
• enlarged lymph nodes_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0000702I129S2SvPasC57BL6NRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmTrp53tm1TyjTrp53Trp53tm1TyjTrp53Rps27lGtIST11658B7Tigm
• small liver_Rps27l<Gt(IST11658B7)Tigm>/Rps27l<Gt(IST11658B7)Tigm>
  http://metadb.riken.jp/0000601C57BL6Rps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7TigmRps27lGtIST11658B7Tigm