Seong Min. Lee, et.al., A humanized mouse model of hereditary 1,25-dihydroxyvitamin D-resistant rickets without alopecia., Endocrinology, 2014, 155

http://rdf.ncbi.nlm.nih.gov/pubmed/25147982

Seong Min. Lee, et.al., A humanized mouse model of hereditary 1,25-dihydroxyvitamin D-resistant rickets without alopecia., Endocrinology, 2014, 155

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(VDR*L233S,luc)T807Pike
  http://metadb.riken.jp/db/mgi_rdf/MGI:5662065

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased bone mineral density_Tg(VDR*L233S,luc)T807Pike/0,Vdr<tm1Mbd>/Vdr<tm1Mbd>
  http://metadb.riken.jp/0000063I129S4SvJaeC57BL6TgVDRL233SlucT807Pike0Vdrtm1MbdVdrtm1MbdTgVDRL233SlucT807PikeVdrtm1Mbd
• decreased circulating calcium level_Tg(VDR*L233S,luc)T807Pike/0,Vdr<tm1Mbd>/Vdr<tm1Mbd>
  http://metadb.riken.jp/0000195I129S4SvJaeC57BL6TgVDRL233SlucT807Pike0Vdrtm1MbdVdrtm1MbdTgVDRL233SlucT807PikeVdrtm1Mbd
• decreased circulating phosphate level_Tg(VDR*L233S,luc)T807Pike/0,Vdr<tm1Mbd>/Vdr<tm1Mbd>
  http://metadb.riken.jp/0000198I129S4SvJaeC57BL6TgVDRL233SlucT807Pike0Vdrtm1MbdVdrtm1MbdTgVDRL233SlucT807PikeVdrtm1Mbd
• abnormal skeleton physiology_Tg(VDR*L233S,luc)T807Pike/0,Vdr<tm1Mbd>/Vdr<tm1Mbd>
  http://metadb.riken.jp/0001533I129S4SvJaeC57BL6TgVDRL233SlucT807Pike0Vdrtm1MbdVdrtm1MbdTgVDRL233SlucT807PikeVdrtm1Mbd
• short tibia_Tg(VDR*L233S,luc)T807Pike/0,Vdr<tm1Mbd>/Vdr<tm1Mbd>
  http://metadb.riken.jp/0002764I129S4SvJaeC57BL6TgVDRL233SlucT807Pike0Vdrtm1MbdVdrtm1MbdTgVDRL233SlucT807PikeVdrtm1Mbd
• increased circulating parathyroid hormone level_Tg(VDR*L233S,luc)T807Pike/0,Vdr<tm1Mbd>/Vdr<tm1Mbd>
  http://metadb.riken.jp/0002904I129S4SvJaeC57BL6TgVDRL233SlucT807Pike0Vdrtm1MbdVdrtm1MbdTgVDRL233SlucT807PikeVdrtm1Mbd
他5件を見る
• rickets_Tg(VDR*L233S,luc)T807Pike/0,Vdr<tm1Mbd>/Vdr<tm1Mbd>
  http://metadb.riken.jp/0003116I129S4SvJaeC57BL6TgVDRL233SlucT807Pike0Vdrtm1MbdVdrtm1MbdTgVDRL233SlucT807PikeVdrtm1Mbd
• increased activity of parathyroid_Tg(VDR*L233S,luc)T807Pike/0,Vdr<tm1Mbd>/Vdr<tm1Mbd>
  http://metadb.riken.jp/0003432I129S4SvJaeC57BL6TgVDRL233SlucT807Pike0Vdrtm1MbdVdrtm1MbdTgVDRL233SlucT807PikeVdrtm1Mbd
• parathyroid gland hyperplasia_Tg(VDR*L233S,luc)T807Pike/0,Vdr<tm1Mbd>/Vdr<tm1Mbd>
  http://metadb.riken.jp/0003493I129S4SvJaeC57BL6TgVDRL233SlucT807Pike0Vdrtm1MbdVdrtm1MbdTgVDRL233SlucT807PikeVdrtm1Mbd
• abnormal epiphyseal plate morphology_Tg(VDR*L233S,luc)T807Pike/0,Vdr<tm1Mbd>/Vdr<tm1Mbd>
  http://metadb.riken.jp/0006395I129S4SvJaeC57BL6TgVDRL233SlucT807Pike0Vdrtm1MbdVdrtm1MbdTgVDRL233SlucT807PikeVdrtm1Mbd
• decreased bone mineral density of femur_Tg(VDR*L233S,luc)T807Pike/0,Vdr<tm1Mbd>/Vdr<tm1Mbd>
  http://metadb.riken.jp/0020010I129S4SvJaeC57BL6TgVDRL233SlucT807Pike0Vdrtm1MbdVdrtm1MbdTgVDRL233SlucT807PikeVdrtm1Mbd

class

http://purl.org/net/cito/citesAsAuthority

• Tg(VDR*L233S,luc)T807Pike
  http://metadb.riken.jp/db/mgi_rdf/MGI:5662065