Jacinthe. Gingras, et.al., Global Nav1.7 knockout mice recapitulate the phenotype of human congenital indifference to pain., PloS one, 2014, 9

http://rdf.ncbi.nlm.nih.gov/pubmed/25188265

Jacinthe. Gingras, et.al., Global Nav1.7 knockout mice recapitulate the phenotype of human congenital indifference to pain., PloS one, 2014, 9

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal nociception after inflammation_Scn9a<tm1Dgen>/Scn9a<tm1Dgen>
  http://metadb.riken.jp/0002736EI129P2OlaHsdBALBcC57BL6orI129P2OlaHsdC57BL6CD1Scn9atm1DgenScn9atm1DgenScn9atm1Dgen
• increased thermal nociceptive threshold_Scn9a<tm1Dgen>/Scn9a<tm1Dgen>
  http://metadb.riken.jp/0001973EI129P2OlaHsdBALBcC57BL6orI129P2OlaHsdC57BL6CD1Scn9atm1DgenScn9atm1DgenScn9atm1Dgen
• abnormal renal/urinary system morphology_Scn9a<tm1Dgen>/Scn9a<tm1Dgen>
  http://metadb.riken.jp/0000516EI129P2OlaHsdBALBcC57BL6orI129P2OlaHsdC57BL6CD1Scn9atm1DgenScn9atm1DgenScn9atm1Dgen
• decreased body size_Scn9a<tm1Dgen>/Scn9a<tm1Dgen>
  http://metadb.riken.jp/0001265EI129P2OlaHsdBALBcC57BL6orI129P2OlaHsdC57BL6CD1Scn9atm1DgenScn9atm1DgenScn9atm1Dgen
• hypoalgesia_Scn9a<tm1Dgen>/Scn9a<tm1Dgen>
  http://metadb.riken.jp/0003043EI129P2OlaHsdBALBcC57BL6orI129P2OlaHsdC57BL6CD1Scn9atm1DgenScn9atm1DgenScn9atm1Dgen
• dermatitis_Scn9a<tm1Dgen>/Scn9a<tm1Dgen>
  http://metadb.riken.jp/0001194EI129P2OlaHsdBALBcC57BL6orI129P2OlaHsdC57BL6CD1Scn9atm1DgenScn9atm1DgenScn9atm1Dgen
• neonatal lethality, complete penetrance_Scn9a<tm1Dgen>/Scn9a<tm1Dgen>
  http://metadb.riken.jp/0011087C129P2B6Scn9atm1DgenScn9atm1DgenScn9atm1DgenScn9atm1Dgen
• increased chemical nociceptive threshold_Scn9a<tm1Dgen>/Scn9a<tm1Dgen>
  http://metadb.riken.jp/0008531EI129P2OlaHsdBALBcC57BL6orI129P2OlaHsdC57BL6CD1Scn9atm1DgenScn9atm1DgenScn9atm1Dgen
• postnatal lethality, incomplete penetrance_Scn9a<tm1Dgen>/Scn9a<tm1Dgen>
  http://metadb.riken.jp/0011086EI129P2OlaHsdBALBcC57BL6orI129P2OlaHsdC57BL6CD1Scn9atm1DgenScn9atm1DgenScn9atm1Dgen
• anosmia_Scn9a<tm1Dgen>/Scn9a<tm1Dgen>
  http://metadb.riken.jp/0004512EI129P2OlaHsdBALBcC57BL6orI129P2OlaHsdC57BL6CD1Scn9atm1DgenScn9atm1DgenScn9atm1Dgen
• abnormal action potential_Scn9a<tm1Dgen>/Scn9a<tm1Dgen>
  http://metadb.riken.jp/0005402EI129P2OlaHsdBALBcC57BL6orI129P2OlaHsdC57BL6CD1Scn9atm1DgenScn9atm1DgenScn9atm1Dgen
• abnormal mechanical nociception_Scn9a<tm1Dgen>/Scn9a<tm1Dgen>
  http://metadb.riken.jp/0002734EI129P2OlaHsdBALBcC57BL6orI129P2OlaHsdC57BL6CD1Scn9atm1DgenScn9atm1DgenScn9atm1Dgen
• neonatal lethality, complete penetrance_Scn9a<tm1Dgen>/Scn9a<tm1Dgen>
  http://metadb.riken.jp/0011087B6129P2Scn9atm1DgenJScn9atm1DgenScn9atm1DgenScn9atm1Dgen
• abnormal synaptic transmission_Scn9a<tm1Dgen>/Scn9a<tm1Dgen>
  http://metadb.riken.jp/0003635EI129P2OlaHsdBALBcC57BL6orI129P2OlaHsdC57BL6CD1Scn9atm1DgenScn9atm1DgenScn9atm1Dgen