Daniel. Herranz, et.al., A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia., Nature medicine, 2014, 20

http://rdf.ncbi.nlm.nih.gov/pubmed/25194570

Daniel. Herranz, et.al., A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia., Nature medicine, 2014, 20

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Rr38<tm1.1Aafo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5750932
• Rr38<tm1.2Aafo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5750934

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased CD8-positive, alpha-beta T cell number_Rr38<tm1.2Aafo>/Rr38<tm1.2Aafo>
  http://metadb.riken.jp/0008079I129S4SvJaeSorBALBcJC57BL6Rr38tm12AafoRr38tm12AafoRr38tm12Aafo
• increased DN3 thymocyte number_Rr38<tm1.2Aafo>/Rr38<tm1.2Aafo>
  http://metadb.riken.jp/0010133I129S4SvJaeSorBALBcJC57BL6Rr38tm12AafoRr38tm12AafoRr38tm12Aafo
• small thymus_Rr38<tm1.2Aafo>/Rr38<tm1.2Aafo>
  http://metadb.riken.jp/0000706I129S4SvJaeSorBALBcJC57BL6Rr38tm12AafoRr38tm12AafoRr38tm12Aafo
• decreased double-positive T cell number_Rr38<tm1.2Aafo>/Rr38<tm1.2Aafo>
  http://metadb.riken.jp/0005092I129S4SvJaeSorBALBcJC57BL6Rr38tm12AafoRr38tm12AafoRr38tm12Aafo
• decreased thymus weight_Rr38<tm1.2Aafo>/Rr38<tm1.2Aafo>
  http://metadb.riken.jp/0004956I129S4SvJaeSorBALBcJC57BL6Rr38tm12AafoRr38tm12AafoRr38tm12Aafo
• decreased thymocyte number_Rr38<tm1.2Aafo>/Rr38<tm1.2Aafo>
  http://metadb.riken.jp/0000715I129S4SvJaeSorBALBcJC57BL6Rr38tm12AafoRr38tm12AafoRr38tm12Aafo
• decreased CD4-positive, alpha beta T cell number_Rr38<tm1.2Aafo>/Rr38<tm1.2Aafo>
  http://metadb.riken.jp/0008075I129S4SvJaeSorBALBcJC57BL6Rr38tm12AafoRr38tm12AafoRr38tm12Aafo
• abnormal thymus physiology_Rr38<tm1.2Aafo>/Rr38<tm1.2Aafo>
  http://metadb.riken.jp/0003763I129S4SvJaeSorBALBcJC57BL6Rr38tm12AafoRr38tm12AafoRr38tm12Aafo
• decreased single-positive T cell number_Rr38<tm1.2Aafo>/Rr38<tm1.2Aafo>
  http://metadb.riken.jp/0008083I129S4SvJaeSorBALBcJC57BL6Rr38tm12AafoRr38tm12AafoRr38tm12Aafo
• thymus hypoplasia_Rr38<tm1.2Aafo>/Rr38<tm1.2Aafo>
  http://metadb.riken.jp/0001823I129S4SvJaeSorBALBcJC57BL6Rr38tm12AafoRr38tm12AafoRr38tm12Aafo
• decreased thymocyte number_Rr38<tm1.2Aafo>/Rr38<+>
  http://metadb.riken.jp/0000715I129S4SvJaeSorBALBcJC57BL6Rr38tm12AafoRr38Rr38tm12AafoRr38

class

http://purl.org/net/cito/citesAsAuthority

• Rr38<tm1.1Aafo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5750932
• Rr38<tm1.2Aafo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5750934